Briggs W, Tamawanacharoen S, Scheel P, Choi M, Nadasdy T,
Racusen L
Clinicopathologic evaluation of prednisone treatment or
patients with HIV nephropathy
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:413 1995
Prednisone therapy at 1 mg/kg/day was instituted in five patients with FSGS
associated with positive HIV, CD4 counts less than 200 and mean serum
creatinines of 11.2 mg/dl. Two of the three hemodialyzed patients failed
to respond, one patient's serum creatinine stabilized, and two patients had
reductions in serum creatinines and degrees of nephrotic proteinuria. The
one patient who had a repeat biopsy showed improved histopathologic
features. The true benefit of prednisone therapy in these patients remains
unclear.
(Krane)
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Am Soc Nephrol
Proteinuria/Hematuria :
HIV-associated nephropathy
Proteinuria/Hematuria :
Focal, collapsing, fibrillary GN