Am Soc Nephrol --Nov: 1995

Selected Abstracts




Hypertension


Preadolescent and adolescent

h Renal mass and blood pressure in normal children

Genetics

h Deletion polymorphism of the ACE gene is a risk factor for target organ damage in essential hypertension

Hormonal aberrations

h Atrial natriuretic peptide is reduced both in white and black salt-sensitive hypertensives
h Endogenous erythropoietin correlates with arterial blood pressure in essential hypertension

Kidney in hypertension

h Nephrosclerosis in the white: no correlation between hypertension and renal histologic lesion
h Microalbuminuria and the renal vascular response to L-arginine in essential hypertension
h Losartan reduces albuminuria in patients with essential hypertension

Ambulatory monitoring

h Diurnal blood pressure variation in normotensive and hypertensive children and adolescents

Tests for LVH

h Left ventricular hypertrophy and systolic dysfunction in non- insulin dependent diabetic patients with and without diabetic nephropathy

Elderly

h Salt loading and hypertension in the elderly

Ethnic populations

h Nocturnal blood pressure in treated hypertensive African Americans compared to treated hypertensive European Americans
h Do racial differences exist for early target organ damage in essential hypertension

Renovascular hypertension

h Outcomes and risks of renal revascularization in azotemic atherosclerotic patients

Renal transplant patients

h In kidney transplanted patients developing graft renal artery stenosis erythrosis appears before blood pressure increases
h Cyclosporine A-induced salt sensitive hypertension: role of nitric oxide

Women

h Birth weight and adult hypertension in women
h Second trimester 24-hour ambulatory blood pressure monitoring: can it predict the development of hypertension in primigravidae?

ACE inhibitors

h Prolonged treatment with the renin inhibitor Remikiren in hypertensive patients with different degrees of impaired renal function

Alpha and alpha/beta blockers

h Captopril and doxasozin induce similar change in renal hemodynamics in hypertensive patients with diabetes mellitus


Dialysis, Chronic Renal Failure


Vascular Access: graft/fistula

d The relation of brachial artery flow to access flow
d The relation of recirculation to access flow
d The relation of intra-access pressure to intra-access flow
d Do patients with angiographically proven access stenosis have low access blood flow?
d Access blood flow measurements in the low flow range by an ultrasonic device are accurate
d A new, Fick-principle based method for measuring blood flow in hemodialysis grafts validated by magnetic resonance angiography
d Access recirculation by ultrasonic dilution compared to a 20 sec slow flow method
d Simplified accurate measurement of access recirculation with an in- line hematocrit device
d Extracorporeal venous drip chamber pressure measurement screening does not predict impending hemodialysis access graft failure
d Increasing AV fistulas for hemodialysis access
d Measurement of access flow by thermodilution: in vitro experiments
d Mutation at Arg506 of coagulation factor V and access thrombosis in hemodialysis patients
d The efficacy and complications of aspirin versus heparin in post-operative prophylaxis against thrombosis in newly placed hemodialysis access

Vascular Access: venous

d Blood recirculation in central temporary catheters for acute hemodialysis

Dialyzers

d In vitro clearance of advanced glycosylated end-products by conventional and high flux hemodialysis membranes

Complications (acute)

d The protective effect of cool dialysate is dependent on patients' predialysis body temperature
d Relationship between blood volume and inferior cava diameter during and after short and long hemodialysis
d The intradialytic effects of oral L-carnitine: results of a double blind placebo controlled trial

Dialysis machines

d Safety of hemodialysis machines: Surveillance of the venous blood return

Home hemodialysis

d Long-term combination home automated peritoneal dialysis and in-center hemodiafiltration for progressive neuropathy in end stage renal disease

Adequacy, prescription, urea kinetics

d Screening for extreme postdialysis urea rebound using the Smye method
d Cardiac index affects urea rebound to the extent predicted by the regional blood flow model
d Effect of intradialytic exercise on urea kinetics and rebound
d Intradialytic exercise increases effective dialysis efficiency and reduces rebound

Physiology

d Fluctuations of urea generation rate following protein intake in hemodialysis patients measured using [13-C]-urea

Reuse, theory and practice

d Heat sterilization of dialyzers: maximized reuse with 1.5% citric acid and 95 degrees C
d Effect of Renalin reprocessing on small and large solute clearances by hemodialyzers

Cardiovascular/Hypertension

d Hypoalbuminemia: a major risk factor for cardiac disease in ESRD
d Hypertension, cardiomyopathy, cardiac morbidity and mortality in ESRD
d Increased homocysteine values, a risk factor for premature coronary artery disease, prevail in patients on hemodialysis
d The effect of fluid loading on blood pressure in hemodialysis patients
d Arteriosclerosis, not atherosclerosis is common in end-stage renal disease: related factors
d Sudden cardiac death and autonomic nerve dysfunction in hemodialysis patients
d Effect of blood pressure on survival in a prevalent cohort of hemodialysis patients

GI/Liver, Hepatitis

d Long-term virological response after alpha-interferon therapy in HCV- positive hemodialysis patients
d Trends in the incidence of hepatitis C infection in hemodialysis units
d Dialysis room and reuse strategies that affect the incidence of hepatitis C infection in HD units
d Beta-2-microglobulin amyloidosis involving the GI tract in hemodialysis

Neurological

d Severe neuropathy predicts mortality in non-diabetic dialysis patients

Anemia/Erythropoietin/Iron

d Role of endogenous erythropoietin in the hematopoietic response to iron administration in hemodialysis patients
d Interferon-gamma mediates resistance to erythropoietin in uremic patients with inflammatory disease
d Response to iron dextran therapy is not precluded by high serum ferritin
d Endogenous erythropoietin levels are elevated in patients on continuous ambulatory peritoneal dialysis
d Factors predictive of suboptimal iron stores in hemodialysis patients with normal iron indices
d Amelioration of left ventricular hypertrophy in long-term hemodialysis patients
d Effect of chronic human erythropoietin therapy on immune response in chronic hemodialysis patients
d Cell therapy for erythropoeitin-deficient anemias
d Underdialysis impairs response to erythropoietin in hemodialysis patients
d Low iron absorption in erythropoietin-treated haemodialysis patients
d Can the erythropoietin dose be lowered safely? A case-control study of subcutaneous administration
d The safety and efficacy of intraperitoneal erythropoietin in children on CCPD
d Correction of anemia does not improve growth or endocrine function in children with ESRD: A report from the U.S. multicenter pediatric recombinant erythropoietin study
d Comparison of 3 iron dextran infusion methods to correct anemia in erythropoietin treated hemodialysis patients

Bone disease/aluminum

d High phosphorus directly simulates PTH secretion by human parathyroid tissue
d Bone mineral loss in chronic renal failure: a difference between young and old CRF patients
d Low-dose DFO treatment (5 mg/kg) in acutely aluminum intoxicated dialysis patients using two drug administration schedules
d Expression in pathalogic parathyroid tissue of calcium receptor and vitamin D receptor gene message
d Expression of Bcl-2 oncoprotein in parathyroid tissue of patients with primary and secondary hyperparathyroidism
d Calcium-regulated parathyroid hormone release before and after successful long-term calcitriol therapy in secondary hyperparathyroidism
d Non-suppressible parathyroid hormone secretion is related to parathyroid gland size in uremic secondary hyperparathyroidism
d Serum phosphorus strongly correlates with PTH in mild chronic renal failure
d Suppression of PTH by 22-oxacalcitriol in hemodialysis patients with secondary hyperparathyroidism
d Marked expression of c-fos/jun proteins in hyperplastic parathyroid glands
d Mild osteodystrophy: Is it really a mild disease?
d Nasal calcitonin reduces bone loss in renal transplant recipients
d Effect of aging on renal responsiveness to parathyroid hormone in healthy men
d In vivo effect of intravenous 1,25-dihydroxyvitamin D3 on interleukin-2 production in hemodialysis patients
d Serum parathyroid hormone levels as a peredictor of the skeletal resopnse to intermittent calcitriol therapy
d Phosphate restriction prevents parathyroid cell growth in uremic rats and high phosphate directly stimulated PTH secretion in tissue culture
d Secondary hyperparathyroidism complicated by parathyromatosis
d Monoclonal proliferation of nodues in parathyroid hyperplasia due to chronic renal failure
d Vitamin D receptor gene polymorphism and severity of secondary hyperparathyroidism

CRF and diabetes

d Depletion of advanced glycated end-products (AGEs) in uremic serum and dialysis fluid by an AGE-binding lysozyme-matrix

Infections (other than hepatitis, peritonitis)

d Hepatitis C viral infection and HIV co-infection in hemodialyzed patients
d Access-related infection in HIV-seropositive dialysis patients: comparison of hemodialysis to peritoneal dialysis
d Preoperative vancomycin prophylaxis decreases the incidence of hemodialysis vascular access infections

Nutrition

d Increased dialysis prescription improved nutrition
d Can we reconcile metabolic acidosis and nutritional status in hemodialysis patients?
d Elevated serum C-reactive protein is a strong predictor of increased mortality and low serum albumin in hemodialysis patients
d Lean body mass estimation by different techniques in healthy controls and peritoneal dialysis patients
d Dialysis adequacy and nutrition in CAPD: a prospective study
d Use of a 1.1% amino acid dialysis solution to treat malnutrition in peritoneal dialysis patients
d Linkage between adequacy of dialysis and nutrition in CAPD patients
d Predictors of malnutrition in maintenance hemodialysis patients
d Effect of insulin-like growth factor 1 on nitrogen balance in malnourished CAPD patients

Outcomes (Morbidity, Mortality)

d Residual renal function in hemodialysis and continuous ambulatory peritoneal dialysis patients
d High cytokine levels may mediate the high mortality of hemodialysis patients with low albumin and cholesterol
d Patient survival on CAPD: comparison between Canada and the United States
d Cardiac disease in endstage renal disease: A comparison of hemodialysis and peritoneal dialysis
d Comparison of mortality risk by Kt/V single pool vs. double pool analysis in diabetic and non-diabetic dialysis patients
d Effect of serial APACHE and organ failure scores on prediction of mortality in acute renal failure
d Association of serum bicarbonate to survival in hemodialysis: a non-linear relationship
d Early death in dialysis patients: risk factors and impact on incidence and mortality rates
d Predictors of short-term mortality in diabetic hemodialysis patients

Complications of PD

d Increased risk of adverse outcome in immunosuppressed patients undergoing CAPD

PD solutions, equipment

d Effect of amino acid based dialysate on peritoneal blood flow and permeability during CAPD
d CAPD using a self-made, ultrafiltration-sterilized, bicarbonate-based solution

PET testing

d Correlation between peritoneal transport type and peritoneal protein losses

Physiology

d Pressure causes fluid loss from the peritoneal cavity to the body
d Effect of acutely raising the serum albumin on peritoneal transport and ultrafiltration in CAPD patients

Peritonitis and exit-site infection

d Bacteria grow better if pH of CAPD solutions is elevated from 5.0 to 6.4, offsetting improvement in neutrophil phagocytosis
d Peritonitis influences mortality in PD patients

Chronic PD regimens, adequacy, modeling

d The creatinine excretion ratio is an unreliable indicator of non- compliance in PD patients
d Urea and weekly creatinine clearances measured by direct quantification: Comparison in APD, CAPD, and conventional HD
d Formula to calculate nitrogen losses in patients treated with chronic peritoneal dialysis
d Comparison of 2 year survival on hemodialysis and peritoneal dialysis with dose of dialysis matched using the peak concentration hypothesis
d Association between adequacy and nutrition in CAPD -- genuine or artifact?

Etiology

d Attribution of hypertension as the underlying cause of ESRD: does race matter?
d Low birth weight a risk factor for development of diabetic nephropathy?

Progression

d ACE gene polymorphism and progression of renal disease
d Urinary transforming growth factor beta-1 and progression of glomerular diseases
d Magnitude of end-stage renal disease in IDDM: 35 year follow-up study
d Effect of dietary protein restriction on the progression of non- diabetic renal disease: meta-analysis

Continous therapies

d Limiting continuous venovenous hemofiltration in acute renal failure
d Treatment of volume overload in patients with acute renal failure by intermittent hemodialysis
d Microspheres for specific adsorption as supplement for hemodialysis in acute renal failure
d Cytokine removal and cardiovascular hemodynamics in patiens with ARF and treatment with CVVH
d Incidence of hypothermia during continuous renal replacement therapy
d Bicarbonate dialysate for continuous renal replacement therapy
d Continuous veno-venous hemodialysis in septic patients


Clinical Nephrology


Reduced circulatory volume/sepsis/hepatorenal

c Is the administration of dopamine associated with adverse outcomes in acute renal failure?
c The role of loop diuretics in acute renal failure? A double- blind, randomised controlled trial

Cyclosporine, ARF in transplant patients

c Thyroid hormone for treatment of acute tubular necrosis in renal allografts: a prospective, randomized trial

Embolic disease

c Focal segmental glomerulosclerosis due to cholesterol atheroembolic disease: Clinicopathologic correlations

Acute glomerulonephritis/RPGN

c Effect of initial histology and plasmapheresis treatment on prognosis in RPGN: results of the German prospective randomized multicenter study
c Superantigen-related glomerulonephritis and vasculitis due to MRSA infection

Acute interstitial nephritis/NSAID

c Renal gallium scintigraphy helps decision-making in acute renal failure

Radiocontrast media

c Effect of hemodialysis after contrast media application in adults with renal insufficiency

Post surgical

c Acute renal failure following cardiac surgery

Urinary tract obstruction

c Distinctive effects between obstructive and non-obstructive pyelocaliectasis by duplex-Doppler ultrasonography

Infections (other than hepatitis, peritonitis)

c Outcome of HIV-infected patients on hemodialysis

Hereditary polycystic disease

c Autosomal dominant polycystic kidney disease patients are at risk for recurrent intracranial aneurysms
c Rate of loss of renal function in hypertensive and normotensive autosomal dominant polycystic kidney disease patients

Hyperkalemia

c Trimethoprim/sulfamethoxazole in standard dose causes hyperkalemia
c Hyporeninemia is associated with erythropoietin deficiency in type I diabetic patients
c Examination for the thiazide-sensitive Na-Cl cotransporter as a candidate gene in Gordon's syndrome

Renal biopsy techniques, tips, complications

c Bleeding time does not predict bleeding complications post renal biopsy
c Timing of complications in percutaneous renal biopsy: what is the optimal period of observation?

Diabetes

c Effect of nondihydropyridine calcium antagonists on progression of nephropathy from non-insulin dependent diabetics: a five year follow-up study
c The ACE gene polymorphism in patients with diabetic nephropathy
c Short-term comparison of ACE inhibition vs. calcium channel blockade in African Americans with type II diabetic nephropathy
c Long-term effect of captopril on kidney function in normotensive insulin-dependent diabetic patients with diabetic nephropathy
c Correlates of diabetic and non-diabetic renal disease in NIDDM
c Smoking -- a major predictor of nephropathy in newly diagnosed type II diabetes
c Kidney/pancreas transplant versus kidney transplant alone
c Efficacy of captopril in normotensive diabetic patients with microalbuminuria - 8 years follow up
c Progression of overt diabetic nephropathy: Role of metabolic control
c Glomerular structure in long term type II diabetes with and without microalbuminuria
c Cyclosporine nephrotoxicity in insulin-dependent diabetic patients: an eight year follow up
c Renal production of TGF-beta is increased in diabetic patients
c Progression of diabetic nephropathy and the insertion/deletion polymorphismof the ACE gene

Focal, collapsing, fibrillary GN

c The impact of plasmapheresis on recurrent focal glomerular sclerosis in renal allografts
c Results of a 6 month randomized control trial of cyclosporine versus placebo in adults with steroid-resistant, idiopathic, focal segmental glomerulosclerosis
c Glomerular number in focal segmental glomerulosclerosis and minimal change nephrotic syndrome

IgA Nephropathy

c The deletion polymorphism in the ACE gene is a risk factor for the progression to renal failure independent of the M235T polymorphism in the angiotensinogen gene
c A family history of hypertension is associated to nephrosclerosis and predicts the future onset of hypertension in patients with IgA nephropathy

Hepatitis-associated nephropathy

c Infection with hepatitis C virus increases the risk of de novo glomerulonephritis in renal transplant recipients
c Serological and virological profiles in renal transplant candidates
c Liver histology in renal transplant patients after more than 10 years of HCV infection
c Localization of HCV in renal tissue of HCV-infected patients with cryoglobulinemic mesangiocapillary glomerulonephritis: an immuno- histochemical study
c Glomerular disease in HIV-infected patients with hepatitis C virus

HIV-associated nephropathy

c Clinicopathologic evaluation of prednisone treatment or patients with HIV nephropathy
c Response to early and prolonged inhibition of angiotensin converting enzyme in HIV-associated nephropathy
c HIV/AIDS as a cause of renal failure
c Contribution of globulins to plasma oncotic pressure and the presence of edema in HIV patients with proteinuria
c Cryoglobulinemia in HIV-infected patients with renal disease
c Captopril increases renal survival in patients with HIV nephropathy
c Absence of edema in HIV-infected patients with ESRD
c Prednisone ameliorates the progression on HIV-associated nephropathy
c Decreasing incidence of severe acute renal failure in patients with HIV infection
c Renal disease prevalence and risk factors among HIV-infected inner city residents
c Are we missing an epidemic of HIV-associated nephropathy?

Lupus nephritis

c Renal lesions in drug induced lupus syndromes

Membranous GN

c Changing incidence of idiopathic glomerular diseases in adults
c Therapy of membranous glomerulonephritis with nephrotic syndrome. Five year follow-up of a prospective, randomized study
c Urinary C5b-9 in early and advanced renal insufficiency in membranous nephropathy

Vasculitis (Wegener's PAN, etc.)

c Assessing the severity of renal disease in systemic vasculitis: how to the histopathologic data predict renal outcome?
c Prevention of relapses in systemic vasculitis
c ANCA-associated vasculitis and renal involvement: preliminary results of a prospective randomized study comparing daily oral versus monthly I.V. cyclophosphamide application
c Humanized monoclonal antibody therapy for Wegener's granulomatosis
c Prevention of relapses of Wegener's granulomatosis by treatment with co-trimoxazole. A placebo controlled trial.
c Outcome of children with ANCA positive glomerulonephritis

Renal Stones: Diagnosis

c Primary hyperoxaluria types I and II: clinical and lithogenic features

Renal Stones: Etiology

c Decreased bone formation in idiopathic hypercalciuric calcium stone formers explains reduced bone density
c A prospective study of dietary and supplemental calcium and the risk of kidney stones in women


UP Use back arrow on your browser to go back to HDCN home page (faster) or click on the arrow.