Jones M, Hagen T, Vonesh E, Moran J
Use of a 1.1% amino acid dialysis solution to treat
malnutrition in peritoneal dialysis patients
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:580 1995
This abstract describes a randomized prospective 3-month trial
comparing standard PD solution to 1.1% amino acid solution and involves
105 patients. The authors find that patients with serum albumin levels in
the lowest tertile show significant benefit from the amino acids as
compared with those treated with standard solutions. Analagous
benefits are not seen in the other tertiles. However, patients in the
highest tertile do show significant improvements in mid-arm muscle
circumference. The authors conclude that IP amino acids are safe and
provide nutritional benefit. A criticism might be that the clinical
significance of these improvements is unclear. There is a need to show
that this sort of nutritional treatment improves long-term outcomes in PD
patients.
(Blake)
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Am Soc Nephrol
CRF by organ system :
Nutrition
Basic peritoneal dialysis :
PD solutions, equipment