Foley RN, Parfrey PS, Harnett JD, Kent GM, Murray DC, Barre
PE
Hypertension, cardiomyopathy, cardiac morbidity and mortality
in ESRD
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:529 1995
Yearly echocardiographic follow-up of 432 dialysis patients
permitted analysis of the relationship between mean arterial
pressure and cardiac structural disease. Each 10 mm Hg rise in
MAP was associated with concentric LV hypertrophy and increase in
LV mass index and cavity volume on follow-up echo. Increased MAP
also was associated with de novo cardiac failure and ischemic
heart disease. Low MAPs were associated with death following
admission for cardiac failure. Thus, the results suggest that
the mortality risk of low MAP in dialysis patients is related to
cardiac failure. The effects of moderate increases in MAP on
mortality are difficult to demonstrate, but this study finds the
well-established link between hypertension and cardiac disease in
this patient population.
(Daugirdas)
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Am Soc Nephrol
CRF by organ system :
Cardiovascular/Hypertension
CRF: Problem Areas :
Outcomes (Morbidity, Mortality)