Fine A, Janzen L, Penner B
The protective effect of cool dialysate is dependent on patients' predialysis body temperature
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:599 1995

The benefits of cool dialysate (35 degrees C) are well known, although some patients do not appear to benefit. In this study 28/128 HD patients were found to have a mean baseline body temp less than 36 degrees C. Such hypothermic patients had less symptomatic hypotension with cool dialysate than with 37 degree C dialysate. However, in 48/128 patients predialysis body temp was greater than 36.5 degrees C. In these patients cool dialysate use was not associated with decreased symptomatic hypotensive episodes. The idea is, that if you're hypothermic to begin with, use of 37 degree C dialysate may warm you up, causing vasodilatation and occasionally, hypotension. If your body temperature is close to 37 degrees C to begin with, use of 37 degrees C dialysate will not cause much of a warming effect, and there will be no adverse hemodynamic effects. In such patients, there is little benefit to be gained from going to a cool dialysate, and, in fact, such patients might be more prone to shivering and feeling cold when cool dialysate is used. (Daugirdas)

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Am Soc Nephrol
Basic hemodialysis : Complications (acute)