Milliner DS, Wilson DM, Smith LH
Primary hyperoxaluria types I and II: clinical and lithogenic
features
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:726 1995
This abstract focused on the long-term outcome of patients with
type 1 or type 2 primary hyperoxaluria. Approximately 9 patients
in each group were studied. Mean age at diagnosis was 15 and 18
years of age for the two groups, respectively. Patients were
followed for 12 and 18 years, respectively. Episodes of
nephrolithiasis requiring surgical intervention were threefold
greater in patient with type 1 PH. During the follow-up period,
3/9 type 1 patients and 1/8 type 2 patients developed end stage
renal disease. The conclusion is that type 1 patients have more
stones and worse renal function than type 2 patients.
Interestingly higher plasma oxalate levels and greater urinary
oxalate excretion rates were noted in patients with type 1
disease.
(Daugirdas)
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Am Soc Nephrol
Nephrolithiasis :
Renal Stones: Diagnosis