Price DA, Gunes B, Turner JR, Lazarus JM, Kay J
Beta-2-microglobulin amyloidosis involving the GI tract
in hemodialysis
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:558 1995
Six hemodialysis patients with deposits of beta-2 amyloid in the
GI tract are described. Presenting clinical findings included
acute abdomen, abdominal pain, diarrhea, nausea, intractable
vomiting, and severe hemorrhage. The mean duration of dialysis
in these patients was 16 years, ranging from 7 to 20 years. All
six had shoulder pain, 5/6 had carpal tunnel
syndrome.
Comment: As dialysis patients survive for
extended periods, amyloid involvement may become a substantial
cause of morbidity.
(Daugirdas)
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Am Soc Nephrol
CRF by organ system :
GI/Liver, Hepatitis
CRF by organ system :
Joint disease, beta-2 microglobulin