Kurokawa K, Akizawa T, Suzuki M, Akiba T, Ogata E,
Slatopolsky E
Suppression of PTH by 22-oxacalcitriol in hemodialysis patients
with secondary hyperparathyroidism
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:966 1995
This study demonstrates the effectiveness of 22-oxacalcitriol in
suppressing PTH with minimal hypercalcemia. In an evaluation of 22 dialysis
patients the authors found that hypercalcemia usually occurred
at doses of drug that were greater than needed to suppress PTH. Thus,
this agent offers a substantial advantage over calcitriol.
(Sherrard)
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Am Soc Nephrol
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Bone disease/aluminum