Germain M, Mulhern J, O'Shea M, Braden G, Madden R, Lipkowitz G, Sweet S, Swidler M, et al.
Bleeding time does not predict bleeding complications post renal biopsy
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:464 1995

Recently the clinical utility of the bleeding time has been questioned (Rodgers and Levin, Semin. Thromb. Hemost. 16:1-20, 1990). Germain et al measured bleeding time post-biopsy in 68 native and 32 transplant renal biopsies, all done under ultrasound guidance using 18-gauge needles. Bleeding was assessed by following Hct and by renal ultrasound immeidately post and 4 hours post biopsy. There was no clinically evident bleeding. 86 patients had BT less than 9 min and 14 had BT greater than 14 min. There was no difference in change in Hct, and all 6 post Bx hematomas by ultrasound were found in patients with BT less than 9 min. The authors conclude that BT is not useful to predict post-biopsy complications.

Comment: Unfortunately, only 14 patients were studied, and the degree of prolongation of the BT was not specified in this group. There may have been very few patients with truly prolonged bleeding times, so this negative study must be interpreted with caution. (Daugirdas)

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Am Soc Nephrol
Proteinuria/Hematuria : Renal biopsy techniques, tips, complications