Kates DM, Sherrard DJ, Andress DL
Serum phosphorus strongly correlates with PTH in mild chronic renal failure
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:965 1995

This study supports recent findings that phosphate may play a direct role in turning on PTH. In mild renal disease, these authors report that PTH rises in association with phosphate, before 1,25 D levels are reduced, suggesting that phosphate may play an important early role in this process. This lends further support for the idea of controlling phosphate very early in the azotemic patient. (Sherrard)

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Am Soc Nephrol
CRF by problem area : Bone disease/aluminum