Salusky IB, Juppner H, Segre GV, Goodman WG
Serum parathyroid hormone levels as a peredictor of the
skeletal resopnse to intermittent calcitriol therapy
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:940 1995
In a group of children on dialysis with hyperparathyroidism, these
authors found that those treated with calcitriol responed quite
differently and this difference related to the baseline PTH. After one
year of treatment, adynamic bone was often found in patients with
baseline PTHs below 1000. With PTH levels greater than 1000,
hyperparathyroidism
often persisted (as seen in bone histology) and the adynamic lesion was
not observed. The authors conclude that the goal PTH level after
treatment remains to be determined.
(Sherrard)
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Am Soc Nephrol
CRF by problem area :
Bone disease/aluminum