Levin NW, Stannard DC, Gotch F, Port FK
Comparison of mortality risk by Kt/V single pool vs. double
pool analysis in diabetic and non-diabetic dialysis patients
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:606 1995
This is a reanalysis of the USRDS Case Mix Adequacy Data set
focusing on the relation between delivered therapy and mortality.
Whereas in previous analyses the single-pool Kt/V was examined,
in this paper the equilibrated or double-pool Kt/V (derived from
the single-pool Kt/V and dialysis session length using the
Daugirdas-Schneditz rate equation) was used. Overall there
appeared to be little benefit regarding survival at double-pool
Kt/V values greater than 1.0. However, there was a trend in
diabetic patients for a survival benefit up to double-pool Kt/V
values of 1.2 (not statistically significant).
Comment: These data suggest that increasing
double-pool Kt/V much above 1.0-1.2 may not be of much benefit to
patients undergoing 3x/week hemodialysis.
(Daugirdas)
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Am Soc Nephrol
CRF: Problem Areas :
Outcomes (Morbidity, Mortality)
Basic hemodialysis :
Adequacy, prescription, urea kinetics