Mulec H, Blohme G, Grande B, Bjorck S
Progression of overt diabetic nephropathy: Role of metabolic control
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:453 1995

191 patients with overt DN were followed for 7.6 years with GFR (CrEDTA). BP and decline in GFR were linearly related, with no safe BP level. HbA1c and decline in GFR were not linearly related; however, patients with HbA1c more than 50% above the normal limit (8.2%) had a more rapid rate of decline of GFR. Glucose as well as BP control appears to reduce progression of DN. (Leehey)

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Am Soc Nephrol
Proteinuria/Hematuria : Diabetes
CRF by problem area : Progression