Iqbal A, Greenberg A, Borochovitz D, Bastacky SI, Johnson JP
Focal segmental glomerulosclerosis due to cholesterol
atheroembolic disease: Clinicopathologic correlations
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:422 1995
The authors retrospectively reviewed 25 renal biopsies. Nine of them were
performed for evaluation of proteinuria, four for progressive renal failure
mimicking RPGN and 12 had typical features of atheroembolic renal disease.
All patients had cholesterol clefts and most had changes consistent with
ischemia. 24% of patients (6) had FSGS, all with significant proteinuria.
The authors conclude that proteinuria specifically with FSGS is a
previously undescribed form of glomerular involvement with atheroembolic
disease and may represent hyperfiltration injury.
(Krane)
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Am Soc Nephrol
ARF etiology :
Embolic disease
Proteinuria/Hematuria :
Focal, collapsing, fibrillary GN