Rao TKS, Friedman EA
Decreasing incidence of severe acute renal failure in patients
with HIV infection
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:474 1995
The yearly incidence of severe acute renal failure (creatinine >6) in HIV
positive and non-HIV positive patients were compared for hospital
admissions to Kings County Hospital Center in Brooklyn, NY from 1984
through 1993. The overall rate of ARF dropped in the HIV positive patients
(2% of admissions 1986-1989, 1% of admissions 1990-1993), while it stayed
the same for non-HIV positive patients (0.2% of hospital admissions during
the same two time periods). The authors conclude that the incidence of ARF
is dropping in HIV positive patients, and speculate that this is due to
greater use of antiretroviral agents, greater awareness of the potential
nephrotoxicity of drugs used to treat HIV patients, more widespread use of
prophylaxis against opportunistic infections and better general care
overall of HIV patients. These speculations are unproved but seem
plausible.
(Pastan)
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Am Soc Nephrol
Proteinuria/Hematuria :
HIV-associated nephropathy
ARF etiology :
ARF: etiology, general