Chapman A, Johnson A, Gabow P, Schrier R
Rate of loss of renal function in hypertensive and normotensive
autosomal dominant polycystic kidney disease patients
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:718 1995
This study evaluated the rate of decline of renal function in
ADPKD patients as a function of their blood pressure. The
hypertensive group (HT, MAP greater than 100 mm Hg) was compared
to a normotensive group (NT, MAP less then 93 mm Hg). Renal
volume, and urinary protein excretion increased in the HT group
over a follow-up period of 3 years but remained stable in the NT
group. In the HT group, serum creatinine increased by 0.1
mg/dl/year, more than in the NT group (0.02 mg/dl/year). The
results suggest that hypertension globally affects deterioration
of renal function in patients with ADPKD.
(Daugirdas)
To go back use the BACK button on your browser.
Otherwise click on the desired link to this article below:
Am Soc Nephrol
Cystic disease :
Hereditary polycystic disease