Chanliau J, Duran P-Y, Mallie J, Kessler M
Urea and weekly creatinine clearances measured by direct
quantification: Comparison in APD, CAPD, and conventional HD
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:860 1995
Chanliau and colleagues have compared total urea and creatinine clearances
in
63 stable anuric HD, APD and CAPD patients by direct quantification of
solutes for each dialysis
technique. Patients on HD received three sessions per week (4h20 +/_ 45 min
each), CAPD patients
used 9.8 liters +/_ 1.0 of dialysate per day, and APD patients (tidal
technique) used 19.6 +/- 4.1
L/day.
Creatinine removal, urea removal, and weekly creatinine
clearances did not differ significantly from one method to another. Weekly
urea clearances were not different on HD vs APD, whereas they were
significantly lower on CAPD. It appears that real HD clearances are much
less than those extrapolated from indirect methods, and that APD can be as
efficient as HD for urea and creatinine removal.
(Verger)
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Am Soc Nephrol
Basic peritoneal dialysis :
Chronic PD regimens, adequacy, modeling
Basic hemodialysis :
Adequacy, prescription, urea kinetics