Pagtalunan ME, Miller PL, Nelson RG, Myers BD, Coplon N,
Jumping-Eagle S, Meyer TW
Glomerular structure in long term type II diabetes with
and without microalbuminuria
Am Soc Nephrol
J Am Soc Nephrol (abstract)
(Nov) 6:454 1995
This study attempted to establish an anatomical link between
microalbuminuria in diabetes as found in Pima Indians and
structural changes in the kidney, notably mesangial cell volume,
glomerular BM thickness, and the number of epithelial cells per
glomerulus. It was found that, in patients with diabetes for
more than 8 years, all of the structural abnormalities were
accentuated relative to those found in patients with diabetes
less than 5 years. However, there was no difference with and
without microalbuminuria. Thus, a structural change associated
with the appearance of microalbuminuria was not identifiable.
(Daugirdas)
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Am Soc Nephrol
Proteinuria/Hematuria :
Diabetes
H: Pathophysiology :
Kidney in hypertension