Pagniez DC, Foucher C, Reade R, Dequiedt Ph
Renal gallium scintigraphy helps decision-making in acute renal failure
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:472 1995

The usefulness of renal gallium scintigraphy to diagnose drug- induced or other acute interstitial nephritis (AIN) is not very clear. In this study gallium uptake was measured in 66 patients with acute renal failure of intrinsic nature. 32 patients had significant uptake bilaterally and biopsy in 14 of these was consistent with AIN. 6 patients had unilateral uptake only, suggesting acute pyelonephritis on one side. The remainder had no uptake and most of them were thought to have ATN.

Comment: The conclusions made are that gallium scintigraphy is helpful in making a diagnosis between ATN and AIN. However, many of the patients were not biopsied and the renal diagnosis remained presumptive. (Daugirdas)

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Am Soc Nephrol
ARF etiology : Acute interstitial nephritis/NSAID
Laboratory tests : Radionuclide scanning