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HDCN News Archive -- Acid-Base
Jul12 Dr. Fred Coe videos on urine calcium supersaturation in stone disease.
Dec14 Even more news on the new HDCN Facebook page!
Dec01 Higher serum Mg associated with decreased risk of sudden death in dialysis patients.
Jun29 Drink when thirsty advice for athletes from Sports Medicine group
Nov17 JAMA: New hyperkalemia sorbent effective in reducing hyperkalemia
Jan14 ZS Pharma announces positive results from extended treatment results of hyperkalemia drug.
Nov19 New study of spironolactone in heart failure fails to show improvement in many hard outcomes.
Nov01 New oral sorbent targeting hyperkalemia; trial results to be presented at ASN.
Oct27 New K-absorbing compound prevents hyperkalemia with spironolactone.
Mar15 New Handbook of Nephrology title available from LWW.
Jan10 Simulated Mars mission reveals body's sodium rhythms
Oct17 Lower chloride use in intravenous fluids may reduce risk of acute kidney injury.
Oct16 Some turtles excrete more urea via the mouth than in the urine.
Sep25 Intravenous hypertonic saline solution reduces inflammation by shrinking cells.
Aug31 Manuscript describing effects of acetic acid and sodium diacetate on acid-base balance now available.
Aug16 Glial lymphatic system identified in the brain.
Aug16 Adjusting and setting the dialysate total base concentration differs by dialysis machine.
Jul23 Higher serum bicarbonate associated with lower type 2 diabetes risk in Nurses Health Study.
Jul11 Artificial Organs journal: Preprint of paper dealing with alkalinizing compounds in bicarbonate dialysate concentrates.
May19 New MRI technique can follow changes in brain pH.
Feb14 Recurrent dehydration may the cause of mystery Central American kidney disease.
Dec20 Elizabeth Barrett Browning had a disease having to do with potassium balance?
Oct26 Kilogram and mole to be redefined.
Oct14 ASN Renal Week 2011 abstracts now available.
Sep28 Use of higher dialysate Na in patients with lower serum Na associates with better, not worse outcomes.
Sep07 Long-distance runners still drinking too many fluids.
May03 Sodium retention action of thiazolidinediones linked to increased proximal tubular absorption.
Mar17 Vasopressin receptors on intercalated cells required for aldosterone effects on hydrogen excretion.
Nov02 Every person emits 2 tons of CO2 each year through metabolism of food.
Oct28 Minocycline prevents osmotic demyelination due to hyponatremia in rats.
Oct22 Salt sensitivity linked to vasopressin via induction of brain protein synthesis.
Sep23 What is "dry water"?
Sep22 Terlipressin treatment for GI bleeding reduces serum sodium levels.
Jul06 How water drinking increases blood pressure and sympathetic activity.
Jun30 What?? Vasopressin does what???
Jun19 Peter Stewart's "Acid-Base Balance" online in full text.
Mar10 JASN paper questions use of ion exchange resins to treat hyperkalemia.
Mar04 JASN study evaluates longer-term treatment of chronic hyponatremia with tolvaptan.
Feb18 JASN: Efficacy and safety of ion exchange resins questioned.
Dec22 Adenylyl cyclase senses bicarbonate levels and regulates blood pH (in dogfish shark)
Dec14 Prussian blue linked to formation of urea, lactic acid and other origins of life molecules.
Nov04 ROMK downstream pathway clarified; may lead to new drugs to combat hyperkalemia in CKD
Oct23 Congenital chloride diarrhea diagnosed by total gene scanning in a young child.
Sep24 AJKD issues containing KDOQI guidelines now freely available as .pdf files
Jul05 Aldosterone regulates ENac levels via Per1 - a protein mediating circadian rhythms.
May26 FDA approves Samsca (tolvaptan) to treat hyponatremia.
May25 Search all abstracts from the World Congress of Nephrology 2009
May19 Guzzlers of large amounts of cola can get muscle weakness due to hypokalemia
May01 Naturally occuring lithium in water supply seems to curb suicide rate.
Apr11 One thousand 2007-2009 audiofiles and slide/audio talks added to HDCN's 20 topic-related channels.
M29 Link to slide/audio and audio symposia on HDCN
F23 FDA warns about risk of metabolic acidosis with epilepsy drug Zonegran (zonisamide)
J30 FDA mandates detailed hyperkalemia warning for Aldactone (spironolactone)
S02 Think your fiance will make the perfect husband? Better first check his vasopressin receptor genotype!
J26 Fist-clenching prior to phlebotomy can raise sample potassium levels.
J22 Ice-tea aficionado develops kidney stones
J22 Woman who claimed water-loading diet caused brain damage due to seizures wins lawsuit.
J21 Adding calcium hydroxide to seawater may reverse global warming.
J25 African Americans excrete less potassium in the urine, and it's not all due to dietary intake.
M05 ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format.
A21 Steven Hebert, renowned Yale nephrologist. In Memoriam
A03 JASN review article in the news: Questions the health benefits of drinking lots of water.
F09 Paradigm shift: Non-osmotic, inflammation-generating accumulation of sodium in the skin
J18 Canadian study suggests drinking 4 liters of water per day can cause proteinuria; reversible when water ingestion reduced.
D04 FDA warns of hyponatremia, seizures, when desmopressin used to treat nocturnal enuresis.
N08 New nonsteroidal natriuretic hormone identified in human urine.
O17 Vaprisol (conivaptan) study shows increase in serum sodium in euvolemic hyponatremia.
A23 Scientist warns marathon runners: Water won't help you keep your cool
M30 Function of Rh blood proteins discovered: link to ammonia excretion.
M27 New blood thinner may work without bleeding risk
J17 Woman dies of hyponatremia after participating in radio-sponsored water drinking contest.
D22 Kidney stones in children no longer a rarity, Johns Hopkins clinicians emphasize.
D01 High urinary sodium and urea concentrations in desmopressin-unresponsive enuresis.
N26 HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts
N15 Tolvaptan paper published in NEJM - novel treatment for hyponatremia.
A25 Benefits of drinking tea touted; dehydrating effect of caffeine-containing beverages questioned.
J16 CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!)
J01 Why does once-heated water freeze more readily? (Mpemba effect)
A28 Magnesium deficiency and metabolic syndrome re-emphasized
A12 Type 2 diabetics have a more acid urine.
A08 Potential brain hibernation protein identified
M17 Obese woman on Atkins with gastroenteritis develops severe ketoacidosis.
F24 Tolvaptan receives FDA fast-track approval status to treat polycystic kidney disease.
J25 Whale lost in Thames River probably died of dehydration and kidney failure.
J12 UK study focuses attention on thiazide-associated hyponatremia and hypokalemia.
J07 CJASN: Serum bicarb and mortality: Is it better to be acidotic or alkalotic?
J04 FDA approves conivaptan (Varprisol) for treatment of euvolemic hyponatremia in hospitalized patients.
D19 Annals paper shows that plasma exchange does not help in ARF due to MM.
D19 Annals paper shows that plasma exchange does not help in ARF due to MM.
D06 Annals paper shows that plasma exchange does not help in ARF due to MM.
N17 Canadian study suggests that drinking too much water can harm kidneys.
O31 Bumetanide may suppress seizures in newborns.
O26 ASN Renal Week 2005 abstracts now available on-line.
O16 NDT: Expect more thiazide-induced hyponatremia after ALLHAT
O16 Small molecule inhibitor of cholera discovered,
O14 Small molecule inhibitor of cholera discovered.
S30 Forced water ingestion to discipline a child may have resulted in her death.
S29 JASN: Acute phosphate nephropathy following certain bowel preps.
A19 MMWR: Hypokalemia and lactic acidosis due to use of adulterated heroin.
J04 Dietary protein, aldosterone, and endothelin linked to renal acidification.
J29 Viagra stimulates insertion of aquaporin channels in collecting duct cells.
J17 Study sheds light on why diabetes drugs (thiazolidinediones) cause edema.
M06 New V2 receptor gene mutations discovered by Gitelman et al at UCSF.
A14 NEJM: Hyponatremia during marathons due to excessive water drinking.
D16 Texas researchers identify elusive kidney acid sensor
N26 Epidemiologic study links high water intake to proteinuria.
N24 Carbonic anhydrase inhibition linked to retinitis pigmentosa
O28 Salt retention gene CYP3A5 polymorphisms vary with distance from equator
O19 Id-3 knockout mice develop Sjögren syndrome-like symptoms
S06 Caffeine intake increases urinary calcium excretion
A07 Rates of spironolactone-associated hyperkalemia increase after RALES Study pub
J21 Did Napoleon die of iatrogenic hypokalemia?
M14 Electrolyte abnomalities in near-drownings in the Dead Sea
O13 Controversies in the treatment of hyperkalemia
S28 ASN 2003 Board Review talks
S26 Fatal lactic acidosis associated with tenofovir
S18 Hyperkalemia and creatinine increases on ACE-I: What should one do?
S12 Manganese in hyperal solutions may be toxic
A22 Hyperkalemia in CHF patients treated with ACE-I and spironolactone
J21 FDA labeling change: use of ARBs with amiloride may increase hyperkalemia risk
J18 Sports medicine authorities clash on how much fluid to drink during exercise
M24 Lithium may reduce production of beta-amyloid (Alzheimer type) in animal models
M22 Altenative drug treatment for manic depression may reduce lithium use
A18 Renal anatomy and overview of nephron function
A03 Thalidomide may benefit patients with early multiple myeloma
M03 Shining red light on retina could prevent methanol-induced blindness
F27 Herbal cleanser contaminated with digitalis-like compound led to hyperkalemia
J17 HDCN acid-base channel lecture list updated
J17 CME/CE quiz, credits available for Arruda potassium talk
A08 Recommendations to drink 8 glasses of water/day challenged
M15 Metformin being given inappopriately to patients with kidney disease
A17 Cystatin no better than creatinine to measure GFR in diabetes
A17 Urinary tract obstruction downregulates aquaporins
A17 Hypercalcemia impairs urine concentration via NaK2Cl expression.
Jul Renal phosphate leak among patients with calcium
Jun Mutations in the Na-Cl cotransporter reduce blood pressure in humans
May Initial effect of sodium bicarbonate on intracellular pH in the ICU
Mar Acute hyponatremia in children admitted to hospital
Mar Bone mineral density and histology in distal renal tubular acidosis
Jan Hyponatremia as a complication of colonoscopy
Jan Risk factors for cerebral edema in children with diabetic ketoacidosis
2000 K-Mg citrate versus KCl in thiazide-induced hypokalemia
2000 ACE inhibition or angiotensin receptor blockade: impact on potassium
2000 A mutation in the Na/HCO3 cotransporter gene (SLC4A4) and proximal RTA
2000 Magnesiuretic potency of twenty-seven oral formulations of diuretics
2000 Physiologic treatment of Bartter syndrome
2000 Why lesions of the loop of Henle (LOH) cause renal potassium (K) wasting
2000 Dietary sodium and effects of potassium depletion on urinary acidification
1999 The human epithelial calcium channel (hECaC) in idiopathic hypercalciuria
1999 Inactivating mutations in the Na-Cl cotransporter mean high bone density