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HDCN News Archive -- Calcium, Phosphorus, PTH, Bone |
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| M14 |
Yale scientists isolate estrogen-like substance secreted by osteoblasts. |
| M07 |
JASN: Calcitriol associated with a lower mortality in pre-ESRD patients. |
| M06 |
Abbott launches investigator-initiated grant program focusing on nonclassical actions of vitamin D receptors: App deadline June 30.. |
| M05 |
CJASN July preview: Niacinamide effective as a phosphate binder. |
| M05 |
ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format. |
| A29 |
Thiazolidinediones (glitazones) may increase fracture risk in diabetics. |
| A23 |
CARE-2 study published on-line in AJKD. CAC progression with calcium acetate plus atorvastatin similar to sevelamer. |
| A17 |
Low serum 25D levels associated with incrased peripheral arterial disease risk. |
| A15 |
Archives Int Med: Loop diuretics associated with lower bone density in men. |
| A12 |
Once yearly zoledronic acid increases lumbar spine density by 4% in glucocorticoid-induced osteoporosis patients; better than risedronate |
| A12 |
Artificial reef approach to strengthening bone. |
| A11 |
Shire Pharma launches On Track phosphate binder adherence toolkit. |
| A09 |
JASN early release: Raloxifene increases bone mineral density in CKD patients. |
| A06 |
Teriparatide (Forteo) gets European regulatory approval for treatment of glucocorticoid-induced osteoporosis. |
| M15 |
Bile acid derivatives shown to strongly activate the VDR receptor without increasing calcium. |
| M13 |
JASN early release: Both low and high 1,25 D levels associated with vascular calcification in kids. |
| M10 |
Gene associated with uric acid transport, blood fructose level, linked to risk of gout. |
| M06 |
Genzyme launches Renvela(TM) - sevelamer carbonate - in the United States. |
| F11 |
FDA approves first generic versions of alendronate (Fosamax) |
| J29 |
BioTrends reports on its survey of changing practice patterns in treating anemia and mineral bone disorder. |
| J28 |
Contrarian view regarding vitamin D supplementation |
| J16 |
Calcium supplements raise risk of heart attacks and stroke in elderly women. |
| J15 |
Osteonecrosis risk with oral bisphosphonates - low or high? |
| J08 |
Risk of cardiovascular events markedly increased when 25-D levels below 15 ng/mL. |
| J02 |
Vitamin D2 as effective as Vitamin D3 in maintaining 25-D levels |
| J02 |
Oral bisphosphonate patients not at high risk for jaw necrosis |
| D17 |
Annals of Internal Medicine: Vitamin D meta-analysis shows no clear benefit on survival in CKD. |
| D08 |
Calcium requirements may be overestimated - should be in the range of 750 mg/day. |
| D03 |
Rosiglitazone stimulates osteoclasts, which may account for association with increased fracture risk. |
| N12 |
Interleukin-1 receptor blocker rilonacept effective in treating chronic gouty arthritis. |
| N08 |
Vitamin D levels linked to telomere length and thus aging. |
| O30 |
Vitamin D benefits may be limited to cancer of the colon |
| O22 |
FDA approves Renvela (sevelamer carbonate) for phosphate control in dialysis patients. |
| O17 |
FDA advisory committee votes in favor of phosphate binder use for stage 4 CKD. |
| O12 |
FDA advisory meeting next Tuesday to study use of phosphate binders in pre-ESRD - Genzyme, Shire, Fresenius will all be present. |
| S07 |
Low vitamin D levels during early pregnancy associated with a fivefold increase in risk of pre-eclampsia. |
| A27 |
Lancet study supports benefit of daily calcium supplements plus vitamin D. |
| A10 |
New research shows skeleton to be an endocrine organ via osteocalcin. |
| J18 |
NEJM: Vitamin D deficiency widespread, linked to a number of chronic diseases. |
| J09 |
JRN: Hidden phosphorus in the diet |
| J27 |
Amgen makes labeling changes for Sensipar - no longer labeled for use in pre-ESRD patients. |
| J26 |
Higher fat mass associated with less coronary artery calcification in type 1 diabetics. |
| J21 |
NEJM: Women aged 50-59 taking oral estrogens have less coronary artery calcification. |
| J20 |
Dietary calcium better than supplements for bone health in women. |
| J19 |
Genzyme announces trial results with powder form of sevelamer carbonate. |
| J05 |
Young women who follow strict diet, exercise regimen at risk for bone loss. |
| M11 |
Low estrogen levels associated with osteoporosis in men. |
| M03 |
Some bisphosphonates associated with increased risk of atrial fibrillation. |
| M02 |
Once-a-year bisphosphonate treatment for osteoporosis. |
| M01 |
Potential downside of calcium / vitamin D intake in the elderly: more stroke-type lesions in the brain. |
| A16 |
Genzyme completes sevelamer carbonate trial. |
| A05 |
Premenopausal overweight women do not lose bone mass during weight loss associated with diet. |
| A03 |
American Kidney Fund launches Medicare Part D program to cover dialysis patient bone meds. |
| A02 |
Ceprotin gets FDA approval to treat purpura fulminans. |
| M24 |
Estrogen protects bone by inhibiting apoptosis of osteoblasts. |
| M21 |
Want to fly to Mars? Watch your bone density! |
| M11 |
Are current recommendations for vitamin D intake way too low? |
| F19 |
Plant-derived omega-3 fatty acids may aid bone health |
| F04 |
Annual Dialysis Conference 2007 abstracts (Denver, Feb 18-20, 2007) |
| F01 |
Biotrends report of Dec 2006 survey on use of ESAs and phosphate binders. |
| J30 |
One in eight men over age 50 found to have osteoporosis |
| J22 |
Prozac and paxil associated with increased risk of falls and fractures |
| J09 |
Two Wisconsin companies get together to develop ingested products for hyperphosphatemia control. |
| J08 |
RIND study published in KI shows decreased mortality in new hemodialysis patients randomized to sevelamer (Renagel) |
| J04 |
Genzyme files new drug application with the FDA for sevelamer carbonate. |
| J03 |
Jaw cortex width of less than 3 mm on dental X-rays is a good marker for osteoporosis |
| D26 |
Use of proton-pump inhibitors associated with increased risk of hip fracture. |
| D22 |
Kidney stones in children no longer a rarity, Johns Hopkins clinicians emphasize. |
| D21 |
Genzyme files for FDA approval of sevelamer carbonbate - Renvela. |
| D20 |
Nanoparticles, kidney stones, vascular calcification, and calcifying bacteria: Mayo Clinic study suggests some links. |
| D12 |
Diet resulting in 10% body weight loss leads to measurable loss in bone density over 1-year period. |
| D09 |
New gene target identified that can markedly increase bone mass. |
| N26 |
Osteoporosis in men in the news. |
| N26 |
HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts |
| N21 |
CARE-2 study results suggest that PhosLo plus statin similar to Renagel in terms of vascular calcification. |
| N18 |
Is lanthanum carbonate (Fosrenol) good for the bones? |
| N15 |
Fresenius completes acquisition of PhosLo from Nabi. |
| N14 |
Genzyme calls for research proposals for its grant program |
| N14 |
Homocysteine, B vitamin link to osteoporosis to be investigated in UK study. |
| O18 |
NABI announces positive results from PhosLo in stage 4 CKD |
| O13 |
Serotonin reuptake inhibitors increase bone mass. |
| O12 |
Fresenius to buy calcium acetate phosphate binder from Nabi. |
| O06 |
Drinking cola tied to bone loss in women |
| S20 |
Does vitamin D protect the kidney against diabetes? |
| S19 |
Demographic data suggest that sunlight exposure via vitamin D lowers kidney cancer risk. |
| A10 |
Genzyme suing Bone Care employees who started Cytochroma to make new D derivatives. |
| A04 |
Oral bisphosphonate risk slight, but dental patients should be aware. |
| J31 |
Studies in mice show mechanism of steroid-related osteoporosis (cortisone receptors on osteoclasts). |
| J31 |
American Kidney Fund and Genzyme announce Medicare Part D assistance fund for Renagel |
| J21 |
Fresenius to debut calcium-acetate / magnesium-carbonate phosphorus binder in Germany. |
| J18 |
EDTA-ERA: New data shows effectiveness of lanthanum (Fosrenol) |
| J18 |
EDTA/ERA: Phosphate control with calcium acetate superior to that with sevelamer. |
| J02 |
Cytochroma acquires Proventiv Therapeutics to commercialize new Vitamin D products for CKD market |
| J01 |
Keryx announces completion of phase 2 dose-finding results for iron-based phosphate binder Zerenex. |
| J22 |
Research identifies protein in mice that regulates bone formation |
| J16 |
CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!) |
| J08 |
Fruit and vegetable intake has beneficial effects on bone via many mechanisms. |
| J06 |
Regulation of NFAT1c - a new way to build bone. |
| J06 |
Calcium from foods important to bone health |
| J06 |
Links between smoking and osteoporosis becoming more clear. |
| J03 |
Vitamin D3 reduces thrombotic risk in cancer patients |
| M30 |
It's the magnesium, stupid! |
| M24 |
Low-carbohydrate diet has no deleterious effects on bone loss. |
| M22 |
Low vitamin D consumption linked to reduced lung function in otherwise healthy teenagers. |
| M17 |
Link to the paper from India about niacin and phosphorus control |
| M17 |
Why not niacin as a phosphate binder? |
| M13 |
Nabi management survives takeover attempt by hedge fund operators. |
| M12 |
Genzyme says petition against Renagel inaccurate |
| M11 |
Texas nephrologist reports serious GI side effects associated with Renagel to the FDA. |
| M08 |
25-OH D3 deficiency in CKD patients is widely prevalent |
| A25 |
Low vitamin D intake during pregnancy linked to low birth weight |
| A25 |
Low vitamin D intake during pregnancy linked to low birth weight - an issue for pregnancy in CKD patients? |
| A04 |
Vitamin D and calcium may lower risk of developing type 2 diabetes in women. |
| A04 |
Low vitamin D levels associated with increased cancer incidence. |
| M28 |
Growing body of research links lead exposure to osteoporosis |
| M17 |
New vitamin D anticancer effects may be separable from its bone effects. |
| F24 |
Nabi reports Q4 results - discloses future plans. |
| F22 |
NEJM: RANK ligand inhibitor denosumab increases bone density in osteoporosis. |
| F20 |
High aluminum levels linked to multiple sclerosis. |
| F16 |
Calcium and vitamin D supplements in postmenopausal women don't reduce fracture risk. |
| F08 |
Vitamin D inhibits progression of some prostate cancers |
| F01 |
Calcium citrate plus weight-bearing resistance exercise builds bone density in women. |
| J24 |
Archives: Chronic warfarin use increases risk of bone fracture. |
| J15 |
Vitamin D therapy in chronic kidney disease patients |
| J02 |
How is marijuana linked to osteoporosis? New role for cannabinoid receptors. |
| D28 |
Vitamin D can lower cancer risk |
| D26 |
Alcohol causes osteopenia - by inhibition of osteoblasts. |
| D21 |
Magnesium intake linked to stronger bones in elderly Caucasians. |
| D15 |
Bifidobacterium infantis now available for IBS: Does it benefit ESRD pts? |
| D15 |
Alcoholism-induced bone disease: toxic effects of ethanol on osteoblasts. |
| D14 |
High TGF-beta levels linked to weak bone matrix in animal studies. |
| D12 |
Higher vitamin D linked to higher lung capacity. |
| D09 |
Vitamin D3 helpful in treating resistant asthma in humans. |
| N30 |
DCOR study results show some benefit in terms of hard outcomes for Renagel. |
| N28 |
Higher dose of Fosrenol (lanthanum carbonate) approved by FDA for ESRD patients. |
| N24 |
Osteoporosis associated with six-fold increase in risk of heart disease. |
| N21 |
Vitamin D supplementation cuts risks of falls in the elderly. |
| N21 |
ASN abstract suggests that even Renagel patients need some calcium. |
| N19 |
Bisphosphonates improve periodontal disease. |
| N15 |
Amgen's RANK ligand inhibitor, denosumab, markedly improves bone density. |
| N15 |
Genzyme requests grant proposals for its Renal Innovations Program |
| N13 |
ASN: 6-year follow-up of patients taking Fosrenol shows encouraging results. |
| N09 |
Vitamin D levels modulate calcium intake effect on PTH suppression in nonuremics |
| N06 |
Vitamin D linked to improved survival after lung cancer surgery in the summer. |
| N01 |
Vitamin D compounds show promise in prostate cancer prevention. |
| O26 |
ASN Renal Week 2005 abstracts now available on-line. |
| O24 |
Shire highlights publication of 1 and 3-year Fosrenol extension study. |
| O07 |
New NKF bone disease guidelines released; emphasis on CKD kids. |
| S28 |
Nabi sues Ohio company for patent infringement over generic calcium acetate. |
| S26 |
Genzyme could see upside if Renagel included in Medicare Part D. |
| S06 |
Calcium scans can predict heart disease in healthy men. |
| S01 |
Calcitriol plus NSAIDs slow prostate cancer cell growth in vitro. |
| A25 |
Brain interleukin-1 levels related to bone dynamics and osteoporosis. |
| A19 |
Novartis trying to develop alternative phosphate binding drug. |
| A11 |
NEJM: PTH(1-34) given with alendronate improves bone density. |
| A11 |
NEJM: Alendronate after PTH(1-84) help maintain bone density. |
| A11 |
400 IU vitamin D may not be enough. |
| A02 |
Are some patients overdosing on calcium supplements and vitamin D? |
| J28 |
Genzyme announces preliminary results of Renagel-mortality study. |
| J26 |
Vitamin D supplements do not improve BMD in Afr. American, nonuremic women. |
| J07 |
More on Nichols vs. Scantibodies PTH assay patent infringement suit (pdf) |
| J07 |
Scantibodies wins in PTH assay patent infringement suit brought by Nichols (4th story down) |
| J30 |
Genzyme, Bone Care International, announce shareholder approval of merger. |
| J23 |
Vitamin D deficiency in CKD - why should we care? |
| J16 |
Genzyme and Bone Care International on track for their merger. |
| M27 |
Abbott announces FDA approval of Zemplar (paricalcitol) capsules. |
| M22 |
Cannabis receptors present in bone; linked to bone loss. |
| M21 |
Compelling evidence mounts for anticancer effects of sunshine via vitamin D. |
| M04 |
Genzyme to buy Bone Care International for 600 M. |
| M04 |
Abbott presents Zemplar data on CKD patients. |
| M03 |
Extensive calcification in uremic rats given non-hypercalcemic dose calcitriol. |
| A28 |
Calcium and vitamin D3 alone fail to prevent fractures in the elderly. |
| A26 |
Charles Bishop returns to Bone Care International |
| A22 |
UCLA researchers discover new molecule that generates bone. |
| A21 |
Fosrenol competing with Renagel for phosphate binder market |
| A17 |
Soy isoflavones have no beneficial effect on calcium metabolism in women. |
| A13 |
J Ren Nutr: Phosphorus content of popular beverages |
| A06 |
New interleukin-related kinase in osteoclasts linked to osteoporosis. |
| A04 |
Cholesterol lowering drugs may lower IC calcium and inhibit proliferation. |
| M29 |
More Vitamin D may benefit housebound elderly. |
| M29 |
Bones in raw food vegetarians are light; may be stronger than expected. |
| M25 |
JASN study in the news about vitamin D and patient survival. |
| M25 |
ESRD patients treated with Vitamin D show longer survival. |
| M01 |
American Kidney Fund and Genzyme announce new patient assistance program. |
| M01 |
JASN: VItamin D injections improve survival in dialysis patients. |
| F21 |
Beta-blockers may prevent osteoporosis via leptin-mediated mechanism |
| F17 |
Vitamin D may ward off prostate cancer. |
| F03 |
Another lanthanum-based phosphate binder in development. |
| J19 |
Amgen's next blockbuster drug - for osteoporosis. |
| J13 |
Soul singer Isaac Hayes unveils new cookbook featuring low-phosphorus foods. |
| J13 |
Concerns arise about excess intake of vitamin A. |
| J11 |
Genzyme reports strong Q4 revenue growth. |
| J07 |
UV light exposure in tanning salons linked to higher bone mass. |
| D28 |
High calcium intake from supplements can increase calcium oxalate stone risk. |
| D23 |
Teva pharma reacquires marketing rights to IV calcitriol in the U.S. |
| D14 |
IV bisphosphonates linked to osteonecrosis of jaw. |
| D10 |
New aluminum-related warning labels for antiperspirants re dialysis patients |
| D07 |
Human parathyroid gland probably evolved from gills of fish. |
| D01 |
Dental X-rays are a sensitive way to identify osteoporosis. |
| N09 |
Gambro gets DOJ subpoena as well regarding vitamin D usage |
| N01 |
Quest Diagnostics gets DOJ subpoena related to Nichols Lab PTH tests |
| N01 |
Genzyme calls for research proposals for grant program |
| O31 |
Complex cause for brittle bones |
| O30 |
ASN: Sevelamer reduces coronary calcification in new dialysis patients |
| O30 |
ASN: Hectorol phase III results in CKD |
| O30 |
ASN: Fosrenol maintains bone health on longer term use |
| O29 |
Bone Care International receives DOJ subpoena |
| O29 |
New theory as to how estrogens protect bone mass |
| O28 |
European Commission approves Mimpara (cinacalcet) for use |
| O27 |
Bone Care Int;l. reports Q1 results |
| O27 |
U.S. FDA approves Fosrenal (lanthanum carbonate) for ESRD patients |
| O26 |
KDIGO.org website now up for international kidney disease guidelines |
| O05 |
Nabi announces PhosLo CARE 2 study - Lipitor in both groups |
| O04 |
Abgenix monoclonal antibody successful in phase I tx of hyperparathyroidism |
| O04 |
Amgen RANK ligand antibody drug improves bone density in osteoporosis |
| S20 |
Genzyme launches Renagel REACH program, expanding access for Medicare pts. |
| S15 |
Myostatin knockout muscle-mice used to study osteoporosis |
| S15 |
Beta-blocker use associated with lower risk of bone fractures |
| S12 |
Chronic hyperphosphatemia elevates fibroblast growth factor levels |
| S09 |
Renagel patient assistance program fall enrollment information |
| A26 |
NEJM: Bones OK in kids after steroid treatment of nephrotic syndrome |
| A09 |
Vitamin D receptor gene polymorphisms related to prostate cancer risk |
| A04 |
Axillary approach may offer new cosmetic alternative for parathyroidectomy |
| A03 |
Abbott submits p.o. Zemplar to the FDA for approval to treat early hyperPTH |
| A03 |
Bone Care posts record sales of its Hectorol vitamin D derivative |
| J30 |
Cinacalcet (Mimpara) receives positive regulatory opinion in Europe |
| J27 |
Dr. DeLuca, pioneer in Vitamin D, and technology patents at U Wisconsin |
| J22 |
Abbott partners with Dr. DeLuca to develop vitamin D receptor activators |
| J20 |
FDA action date for Fosrenol extended from July to October of this year. |
| J07 |
Adynamic bone associated with vascular calcification |
| J05 |
Alcohol may protect bones against osteoporosis. |
| J10 |
Nabi launches study of Phoslo (calcium acetate) plus Lipitor |
| M27 |
US FDA approves paricalcitol (Zemplar) for use in kids with ESRD |
| M13 |
NEJM: Homocysteine levels, B vitamins, linked to osteoporotic fracture risk |
| A28 |
FDA approves Hectorol indication to treat SHPT in stage 3 and 4 CKD |
| A13 |
NKF unveils K/DOQI bone disease guidelines tools for professionals |
| A08 |
Cinacalcet paper published in NEJM |
| A06 |
BMP-7 injections restore bone loss in mice with CKD |
| M29 |
Are we getting enough vitamin D? |
| M24 |
Fosrenol (lanthanum carbonate) wins regulatory approval in Sweden |
| M17 |
Alendronate continues to work in osteoporosis up to 10 years |
| M08 |
Sensipar (cinacalcet) approval news release (Amgen) |
| M08 |
U.S. FDA approves Amgen's cinacalcet to treat secondary HPT |
| M03 |
Vitamin B12 deficiency linked to osteoporosis in elderly women |
| F21 |
Genzyme profits soar on Renagel sales |
| F16 |
Amylin protects against bone loss |
| F16 |
Bone med protocols from ESRD Network 11 |
| F16 |
Bone med protocols from ESRD Network 11 |
| F16 |
Bone med protocols from ESRD Network 11 |
| F06 |
Stroke risk also higher for kids in Southeast US stroke belt |
| F06 |
Bone morphogenetic protein prevents adynamic bone disease in CKD mice |
| J29 |
NEJM: Strontium ranelate slows osteoporosis, reduces fracture risk |
| J18 |
Can people keep bones strong in old age? Bears may have the answer |
| J13 |
Genzyme reports strong revenue growth |
| J09 |
New bone mineral density gene identified in mice |
| D10 |
Undetermined muscle/bone pain linked to severe vitamin D deficiency |
| D09 |
Shire licenses Fosrenol (lanthanum carbonate) rights in Japan to Bayer |
| D03 |
NKF: K/DOQI bone metabolism guidelines now on-line |
| N15 |
Amgen gets FDA priority review for cinacalcet; positive results shown at ASN |
| N13 |
Genzyme calls for research proposals fror renal innovations program |
| N05 |
Debate about raising the RDA for vitamin D amid widespread deficiency |
| N05 |
New bone formation seen in osteoporotics treated with PTH |
| N03 |
Iceland gene screen identifies BMP2 as important factor in osteoporosis |
| O09 |
Low sunlight exposure leading to vitamin D deficiency epidemic in the U.S.? |
| O01 |
New K/DOQI guidelines on bone disease published as October supplement in AJKD |
| S21 |
NEJM early release: Alendronate may impair anabolic effects of PTH |
| S09 |
Amgen submits new drup app to FDA for new calcimimetic Cinacalcet |
| A31 |
Up to 20% of adolescents may be vitamin D deficient |
| A26 |
Indomethacin stops phosphate-wasting in X-linked hypophosphatemic mice |
| A23 |
Abbott to spin off hospital products business into separate company |
| A15 |
Zemplar (paricalcitol) may boost effectiveness of prostate cancer treatment |
| A05 |
Interferon gamma may explain estrogen-withdrawal osteoporosis |
| A05 |
Nabi acquires PhosLo (Ca acetate) from Braintree Labs |
| A04 |
Genzyme buys Sangstat for 600 M |
| J30 |
NEJM: Mortality lower in dialysis patients taking paricalcitol than calcitriol |
| J22 |
Osteoporosis in men being given increased attention |
| J16 |
Genzyme reports revenue gain on strong sales of Renagel and Fabrazyme |
| J30 |
Lanthanum carbonate (Fosrenol) trial results published in July AJKD |
| J12 |
3-year experience with lanthanum carbonate (Fosrenol) presented at WCN in Berlin |
| M19 |
Chugai plans to start selling Renagel in Japan next month |
| M14 |
Kidney Int Sup: Advances in Renal Osteodystrophy |
| M13 |
Lanthanum carbonate (Fosrenol) shows favorable effects on bone |
| A14 |
Obesity surgery may lead to weakened bones |
| A04 |
NKF: Long-term Fosrenol (lanthanum carbonate) controls serum phosphorus in HD |
| A03 |
Vitamin D improves calcium absorption even with normal serum vD levels |
| M26 |
Chapel Hill company (AaiPharma) launches sale of injectable calcitriol |
| M26 |
Study links bone loss, elevated blood lead levels |
| M21 |
Scleritis identified as a possible side effect of bisphosphonates |
| M10 |
FDA accepts Hectorol injection manufacturing submission |
| M04 |
Hibernating black bears give new clues to recovery from osteoporosis |
| M04 |
New hints into development of osteoporosis |
| M03 |
Shire says FDA has given them an approvable letter for Fosrenol for PO4 binding |
| F27 |
European Union review of Shire's Fosrenol lanthanum phosphate binder delayed |
| J20 |
Vitamin D deficiency may play a role in heart failure |
| J11 |
Bone Care (maker of Hectorol) to announce 2nd quarter results |
| D20 |
Lead in bones linked to pregnancy blood pressure |
| D17 |
Calcitonin knockout mouse shows increased bone density |
| N03 |
ASN: Oral calcimimetic reduces PTH levels in chronic renal disease |
| N02 |
Beta-blockers, leptin, linked to bone mass, possible role in osteoporosis |
| O24 |
New bone-specific estrogen |