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HDCN News Archive -- CRRT / Acute Renal Failure
J03	NEJM: Scanning the blood for circulating tumor cells using DNA technology helps guide treatment of metastatic disease.
J03	VA/NIH study of dialysis dose in acute kidney failure published in NEJM
J03	Novel antibiotic ceftobirole kills even the most resistant Staph. aureus.
J01	Indocyanine green plus laser light kills even resistant bacteria; application to wound infections.
J26	Two siRNA in the Phase I/II pipeline for kidney disease, one for delayed graft function, the other for AKI
J26	Cethromycin for community-acquited MRSA.
J25	MRSA skin infections becoming commonplace in healthy athletes.
J25	Radiofrequency equipment ID tags can halt dialysis machines, change ventilator settings, alter syringe pump performance in the ICU.
J19	Some pathogenic bacteria use nanosyringe to inject host cells with toxins.
J18	Computer generated warfarin dosing as effective as dosing by expert prescribers.
J18	HHV-8 herpes virus linked to ketosis-prone type 2 diabetes in Africa.
J16	Do patients with combined liver/kidney transplants really need the kidney portion?
J13	FDA and EMEA to consider biomarkers of renal injury in animal studies evaluating renal safety of new drugs.
J06	Nephros completes trial of clip-on hemodiafiltration module and high-efficiency b2-M hemodiafilter.
J05	NEJM: Heparin contaminated with oversulfated chondroitin sulfate causes anaphylaxis via kallikrein activation.
J03	Antibacterial wipes can actually spread drug-resistant bacteria if used on more than one surface.
J03	Salmonella outbreak in 9 states linked to raw tomatoes.
J03	Nova (R) renal - a contrast-free method for visualization of renal perfusion on MR scans.
J03	Magnetic control mechanism developed to steer swallowed mini-cameras for better GI tract images.
J03	Artificial blood vessel creation from smooth muscle cells makes major advances.
M30	Cause of clubbing of the fingers in lung disease found - 15-HPGD.
M28	RIP140 molecule involved in tumor cachexia, fatty liver, and associated inflammation.
M27	New scoring method for coronary artery calcification that takes into account extent of calcium coverage.
M23	Automated CPR machine helps save lives.
M22	FDA approves gut opioid antagonist Entereg, for use to prevent postoperative ileus.
M20	NEJM: Palevsky-VA/NIH study shows that daily HD or more intense CRRT of no benefit in acute kidney injury
M19	Results of VA/NIH study on dialysis dose in acute kidney injury to be presented tomorrow, May 20th, in Toronto at ATS2008.
M19	Silver-coated endotracheal tube use dramatically reduces resistant infections in ICU patients.
M19	Capsaicin plus a derivative of lidocaine cause pain relief without numbness. Will it work for cannulation pain?
M16	Salmlonella infection in people linked to exposure to dry dog food.
M16	MMWR: CDC recommends herpes zoster vaccine for all persons over age 60.
M15	Lower-dose tissue plasminogen activator treatment improves survival in patients with hemorrhagic stroke.
M15	Canadian scientists discover how tuberculosis bacteria evade destruction by macrophages.
M15	Fluvastatin found to markedly lower viral load in hepatitis C.
M13	Preop beta blockers reduce heart attack risk but markedly increase total mortality.
M12	CPR rescuers do not need to stop compression while administering defibrillator shocks.
M12	U.S. Health Secretary: Chinese heparin now should be safe.
M09	FDA reissues heparin alert, since contaminated heparin still stocked in a number of hospitals.
M07	New hospital superbug to worry about: Stenotrophomonas maltophilia
M05	ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format.
M02	Protozoans may ingest E. Coli, and carry them on the surface of vegetables like spinach and lettuce.
M01	MMWR: Acute renal failure associated with cosmetic soft tissue filler injections.
A28	New JAMA study to highlight CV risk of blood substitutes; FDA under renewed pressure.
A28	Hypertension seen in the emergency department frequently misattributed to trauma, stress, and not followed up.
A28	FDA approves Relistor (methylnaltrexone) for opioid-induced constipation.
A23	MIT led teams unravel heparin deaths mystery
A23	NEJM paper (full text) describes mechanism of how oversulfated chondroitin sulfate can cause anaphylaxis.
A23	FDA: Fatal hypoglycemia due to maltose-containing immune globulin causing erroneous blood glucose readings.
A22	FDA approves compact heart assist device from Thoratec.
A17	FDA critical path in process for evaluating biomarkers to detect kidney injury.
A15	FDA warns of selenium, chromium poisoning associated with health supplements.
A15	Archives Int Med: Loop diuretics associated with lower bone density in men.
A15	Salmonellosis associated with Malt-O-Meal cereal ingestion.
A15	FDA announces recall of two dietary supplements found to contain aristolochic acid.
A07	New antimicrobial proteins identified in alligator blood
A07	Mud bath clays may be useful to treat MRSA skin infections.
A03	New Merck heart failure drug rolofylline gives encouraging results in Phase III trial.
A02	Adenosine receptor antagonist shows promise in heart failure.
A02	ExoSeal vascular plug reduces bleeding after arterial catheterization.
A02	Iodixanol (Visipaque) no better in terms of contrast nephropathy for PCI.
A01	Should black box warnings on ultrasound contrast agents be reconsidered?
A01	Bacteriophage-bonded surfaces used in wound dressings to decontaminate MRSA.
M28	MMWR: Discharge diagnosis of kidney disease for hospitalizations increased fourfold between 1980 and 2005.
M27	NEJM: Diaphragm atrophy begins within 18 hours of mechanical ventilation.
M25	European nations recall heparin; safety of alternative heparin supply called into question.
M25	Archives paper highlights renal failure risk of oral phosphate colonoscopy preps.
M25	Inhaled hydrogen sulfide gas induces hypometabolic state in animal model.
M22	Heparin supplied by B. Braun also affected by allergic contaminant problem.
M20	Two week old blood associated with adverse outcomes when transfused.
M13	JASN early release: High dose continuous HDF at 35 ml/kg/hr no better than 20 ml/kg/hr.
M12	Uninterrupted chest compressions during CPR by paramedics lead to increased survival.
M11	Creatine found to be neuroprotective in mouse model of perinatal hypoxia.
M11	Doubts raised over benefits of MRSA screening of hospitalized patients.
M10	With increase in availability from alternative sources, Baxter recalls all heparin products.
M06	Cannabinoid receptor blocker rimonabant prevents ethanol-induced fatty liver in mice.
M05	FDA finds possible contaminant in Baxter heparin.
M04	JASN: Humes' tubular assist device lowers mortality in AKI.
M04	CAPON gene linked to QT interval and heart rhythm abnormalities.
F27	Chewing gum after bowel surgery shortens duration of post-operative ileus.
F27	Up to 20% of persons taking aspirin show no effect on their platelet function.
F26	WHO survey reveals that prevalence of multidrug resistant tuberculosis cases at new high.
F23	Arbios gets conditional approval from FDA to test artificial liver device
F20	JAMA: Metaanalysis shows that intermittent dialysis and CRRT for ARF lead to similar outcomes
F20	New study confirms increased risk of kidney failure and mortality with aprotinin.
F19	Annals: Meta-analysis supports use of acetylcysteine prophylaxis prior to giving radiocontrast.
F15	Some cholesterol synthesis inhibitors also block Staph. aureus pigment synthesis, rendering the germ less pathogenic.
F11	Integrin receptor linked to HIV infection and replication in the gut. Is a treatment already available?
F07	NEJM full text of paper describing new arenavirus in patients dying after kidney or liver transplants.
F05	FDA cautions about severe tissue injury after intravenous administration of promethazine (Phenergan).
F04	CDC ongoing investigation into heparin anaphylactoid reactions summarized in MMWR
F01	Anti-leishmaniasis drug miltefosine kills HIV-infected macrophages, eliminating one protected site of HIV persistence.
J29	Intravascular thrombolytic therapy effective against deep vein thrombosis.
J28	More info about the Baxter recall of 1,000 IU/ml heparin vials due to anaphylactoid reactions.
J25	Update on Baxter heparin recall - one death may have resulted from first-use type anaphylactic symptoms.
J25	Cox-2 inhibitors can cause arrhythmias by affecting potassium channels in the heart.
J24	NEJM: Renal failure due to oxalosis after 2g/day vitamin C for 3 years in a renal transplant patient.
J22	Feeding cattle with ethanol distillation by products (distillers grains) increases risk of toxigenic E.Coli colonization.
J22	Aspirin resistance increases risk of heart attack or stroke.
J22	FDA approves new bioimpedance-based non-invasive cardiac output monitor.
J18	Canadian study suggests drinking 4 liters of water per day can cause proteinuria; reversible when water ingestion reduced.
J16	FDA warns of name confusion between two edetate compounds used for chelation.
J15	Monkey malaria widespread in humans in Southeast Asia - potentially fatal.
J02	FDA clears quick molecular-biology-based blood test for MRSA.
J02	European study could find no link between non-phenacetin pain killers and ESRD
D27	Researchers block liver cirrhosis in a mouse model by use of RSK inhibitory peptide which blocks collagen synthesis.
D27	FDA approves synthetic starch-based volume expander fluid.
D27	Weight-based dosing for ribavirin increases efficacy against hepatitis C.
D27	New orally active cyanide antidotes discovered.
D19	Controlled trial of controlled fluid challenge device (RenalGuard) during contrast infusion to begin.
D15	Sutent (sunitinib), a cancer-fighting tyrosine kinase inhibitor, associated with cardiac toxicity
N28	Eltrombopag increases platelet count in hepatitis C infected patients being treated with antiviral drugs.
N28	Crystal nephropathy due to combination of melamine and cyanuric acid responsible for renal failure in pets eating contamined food.
N27	Glucose-insulin-potassium infusion after ST-elevated MI increases risk of heart failure.
N26	Risk of acute renal failure after non-cardiac surgery in patients with prior normal function is about 1%.
N20	Nephros gets approval to market high-efficiency hemodiafiltration device in Canada.
N19	First-ever trial of RNA interference drug in humans targets acute kidney failure.
N16	MMWR: Severe acute respiratory disease, including death in healthy persons, due to adenovirus 14.
N14	Cattle vaccine shown to be effective in lowering rate of toxigenic E. Coli carriage.
N14	Nephros reports Q3 results
N12	Baxter receives 510k clearance for FDA to test a silver-coated IV line luer-lock connector.
N12	Patent extends principle of self-winding watches to heartbeat powered pacemakers.
N09	Lower abdominal pain in women after binge drinking may be due to bladder rupture.
N08	FDA clears silver-coated endotracheal tube for marketing.
N07	Survival doubles with adoption of new AHA resuscitation guidelines.
N07	New diagnostic test for TTP (thrombotic thrombocytopenic purpura) to be available via Ohio State University.
N07	Perioperative beta-blocker therapy shows mixed results in large RCT.
N07	News is not so good relating to hard outcomes with longer-term treatment of hepatitis C with pegylated inferferon.
N03	General Mills recalls frozen pizzas sold under Totino's or Jeno's name, because of possible E. coli contamination in the pepperoni.
N02	Entecavir highly effective in reducing hepatitis B viremia to undetectable levels.
N02	NephroCor introduces enhanced urine analysis test (RenalVysion) for kidney disease
N02	Cell-to-cell transmission of hepatitis C virus helps it evade some of body's most potent defenses.
N01	New therapies for multiple myeloma result in increased survival.
O29	Maggots to treat diabetic foot ulcers infected with MRSA.
O29	Bacterial use peptides to communicate with each other: extracellular death factor identified.
O25	Bayer issues additional guidance to physicians about Trasylol (aprotinin).
O25	SQ109, promising anti-tuberculosis drug, given special status by European and U.S. regulators.
O23	Renal Solutions gets FDA 510k clearance for advanced sorbent dialysis machine enabling higher dialysate flow rates.
O23	How dangerous is plasma transfusion from women donors?
O19	ARDS of unknown etiology? Look for spirochetes in the peripheral blood smear.
O16	Velcade (bortezomib) for multiple myeloma now approved for use in patients with impaired renal function.
O08	Two studies emphasize importance of nitric oxide in red blood cells, and absence of NO in banked blood.
O08	Appendix may be a safe house for good bacteria.
O08	Cleveland Clinic scores 3.2 million dollar NIH grant to develop implantable bioartificial kidney
O03	Seven Indiana schoolchildren suffered kidney failure requiring dialysis due to toxigenic E. Coli
S27	Caffeine plus acetaminophen linked to liver damage.
S25	Toxin-producing E. Coli outbreak among schoolchildren in Galena, IN.
S25	New, synthetic version of heparin is patented.
S24	C. difficile prevalent in asymptomatic carriers - may account for difficulty in eradication.
S20	FDA Recall: B. Brraun normal saline flush syringes.
S20	Post-reperfusion heart damage largely prevented by hydrogen sulfide.
S18	Dole recalls packaged salad mixes because of E. Coli risk.
S06	New CPR method relies on compression of abdomen, increases CO by 25%.
A19	Bacteriophage treatments coming back into favor to combat superbugs such as MRSA.
A17	Patients who develop kidney failure after use of phosphate-based laxatives initiate lawsuits.
A02	unGAL shown to predict development of acute kidney injury in children
J20	FDA warns about botulism from hot dog chili sauce.
J19	Baxter issues Class I recall of its replacement IV infusion pumps.
J11	Shredded lettuce may be source of toxigenic E. Coli outbreak in Huntsville, AL.
J10	More than 1100 toothpaste tubes from China suspected to contain DEG confiscated in Connecticut.
J09	PNAS: Aristolochic acid in the pathogenesis of endemic Balkan nephropathy.
J09	Cause of Balkan nephropathy found - contamination of grain by Aristolochia clematis.
J09	FDA warning: precipitation when infusing ceftriaxone with calcium-containing solutions.
J09	Slime busting bacteriophage virus could clean up biofilm.
J07	Waging war on C. difficile - the deadliest superbug.
J02	Probiotics good for antibiotic-induced diarrhea
J29	Particulates released during renal artery angioplasty can impair kidney function.
J28	Distribution of made in China, DEG-contaminated, toothpaste, in the United States includes prisons and hospitals.
J28	Velcade (bortezomib) in combination with cyclophosphamide and prednisone for multiple myeloma.
J26	Ketamine abuse linked to bladder dysfunction.
J22	Dangers of children ingesting hand sanitizers with high alcohol content
J19	FDA approves ambrisentan for treatment of pulmonary artery hypertension.
J15	Ethylene-glycol contaminated toothpaste found in Baltimore, MD store.
J15	Family sues Con Agra over salmonella contamination of peanut butter that allegedly led to kidney failure.
J09	Methylsalicylate absorption from sports cream results in teenager's death
J02	FDA warns on toothpaste marketed in the U.S. that was made in China over DEG contamination fears.
M23	More on the FDA gadolinium-contrast agent warning
M23	FDA orders black box warnings for gadolinium-based MRI contrast agents regarding NSF.
M17	Lawmakers push for changes in food safety oversight.
M09	FDA issues warning about potential diethylene glycol contamination of glycerin.
A30	Guelph scientists explain how pet food tainted with melamine and cyanuric acid can cause kidney failure.
A30	Compound from bullfrogs has marked anti-MRSA activity.
A21	Abstracts from March, 2007 CRRT meeting in San Diego.
A18	MMWR: Severe community-acquired MRSA pneumonia in association with influenza.
A17	New hope for malaria treatment with synthesis of long-acting artemisinin-like trioxane drugs.
A05	Reperfusion with glucose responsible for brain damage after hypoglycemic coma.
M30	Function of Rh blood proteins discovered: link to ammonia excretion.
M29	Aspirin may cut Staph risk in dialysis patients with venous catheters.
M23	Aminopterin found in tainted pet food.
M21	FDA approves hydroxocobalamin to treat cyanide poisoning.
M21	Spraying "essential oils" into the air reduces prevalence of MRSA in a hospital setting.
M16	FDA issues Medwatch SafetyAlert on linezolid (Zyvox) due to increased mortality rate
M16	Substituting gallium for iron impedes growth of slime-forming bacteria.
M13	Copper in doorhandles and hospital fixtures may fight MRSA
M12	Azole antifungal drugs found to be active against tuberculosis.
M09	MMWR reports on invasive MRSA infections in dialysis patients.
M08	UK National Health Service launches tool to help prevent infections in dialysis units.
M05	Taking amphotericin B in oil by mouth may result in good efficacy, less renal toxicity.
M03	Search Society for Interventional Radiology abstracts (2002-2006) (use keyword -dialysis-)
M02	NEJM: Vancomycin-induced thrombocytopenia: the article link
F28	Abstracts from 2007 CRRT meeting, March 7-10 in San Diego, CA
F28	NEJM: Immune-mediated thrombocytopenia linked to vancomycin use.
F26	Distinctive odor of diarrhea may lead to rapid diagnostic test for Clostridium and Campylobacter infection.
F04	Annual Dialysis Conference 2007 abstracts (Denver, Feb 18-20, 2007)
F04	International Center / Website for nephrogenic fibrosing dermopathy.
J29	Nephros gets conditional FDA approval to test hemodiafiltration module in the US
J29	Bacteriophages and antibiotics exhibit synergistic effect; may lower needed dose by a factor of 50.
J28	New necrotizing toxin identified in dangerous, community acquired strain of multidrug-resistant Staph. aureus
J26	Radiology journal to recommend avoiding gadodiamide in patients with kidney disease because of nephrogenic systemic fibrosis
J19	Potentially lethal strains of MRSA spreading to the community in the UK
J17	Hyperimmune response to 1918 flu virus is what made it so deadly.
D27	Cattle vaccine against E. Coli O157:H7 approved for use in Canada.
D22	FDA announces that it is still evaluating a possible link between MRA with gadolinium and nephrogenic fibrosing dermopathy.
D22	Prion-binding protein successfully removed variant CJD prions from banked animal blood.
D22	Multidrug resistant E. coli linked to antibiotic use on farms in the U.K.
D20	FDA to require labeling changes for acetaminophen and for NSAIDs to highlight potential risks.
D16	FDA updates labeling for Trasylol (aprotinin) regarding risk of renal dysfunction, anaphylaxis, and re-exposure.
D15	Common cold rhinovirus leads to death in two lung transplant recipients
D14	Role of heat shock proteins and fever in fighting infections clarified.
D04	New diagnostic recommendations published for diagnosis of pulmonary embolism.
D04	Toxigenic E. Coli outbreakds in New Jersey and Long Island linked to fast food outlets.
N26	HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts
N15	Tolvaptan paper published in NEJM - novel treatment for hyponatremia.
N07	Endotoxin core in bacteria linked to plant chloroplasts
O30	Vaccine protects mice against multidrug resistant Staph aureus.
O24	RCT initiated to study benefits of endovascular cooling during catheterization to prevent RC nephropathy
O13	Diethylene glycol-tainted cough syrup cause of multiple deaths, renal failure, in Panama.
O12	Human carriage of drug-resistant microbes linked to consumption of poultry
S28	Invasive streptococci produce a protein that destroys interleukin-8 and impedes WBC recruitment.
S27	CDC-MMWR: O157:H7 infections associated with consumption of fresh spinach.
S16	Spinach E. Coli scare grows
S15	Toxigenic E. Coli outbreak tied to bagged spinach - people affected in 8 states.
S13	More bad news in JAMA paper about CV and kidney risks of COX-2 inhibitors and NSAIDS
S11	New genetic method to detect early multiple myeloma
S08	MMWR: Locally acquired, mosquito-transmitted malaria in California and other states.
S05	U.S approves humanitarian use of Abiocor permanently implanted total artificial heart.
A19	Spray on bacteriophages approved to control Listeria on meat; toxigenic E. Coli next on the list.
A18	Genetic clues to cardiomyopathy and sudden death found in mice - emphasis on the right ventricle
A18	NEJM: Daptomycin as good as gent + vanc for Staph. aureus endocarditis
A16	Antibiotic skin infections becoming commonplace
A10	Mayo Clinic researchers come up with consensus for use of bisphosphonates in multiple myeloma.
J31	MMWR: New multidrug-resistant strain of HIV identified in New York
J06	Statins inhibit replication of hepatitis C virus
J05	Liver damage due to moderate doses of acetaminophen highlighted in JAMA paper
J03	Fish oil emulsion instead of Intralipid (soybean oil) for parenteral nutrition prevents/reverses liver damage.
J28	NEJM: Acetylcysteine protects against contrast nephropathy in angioplasty patients
J24	Does coffee protect against alcoholic cirrhosis?
J16	CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!)
J14	Hyperglycemia in non-diabetic ICU patients predictive of mortality, esp. in cardiovascular disease
J08	Renal Solutions reincarnates a newer, better Redy cartridge system for home and ICU dialysis.
J06	Mayo clinic shows that thalidomide plus dexamethasone for multiple myeloma gives better results.
J06	FDG PET useful in detecting hard-to-detect chronic osteomyelitis
M30	It's the cooling of the blood in the extracorporeal circuit, stupid!
M17	Superbug slain by soil antibiotic
M13	E. Coli O157 recovered from bagged salad: cause diarrhea with ARF
A28	Does chamomile tea interact with warfarin?
M30	Strangers' prayers found to offer no benefit for recovery of heart bypass patients from surgery.
M24	MMWR: Fatal lead poisoning in a child from ingestion of a lead charm from a bracelet.
M08	NEJM: In multiple myeloma, thalidomide is of marginal additional benefit to melphalan/autologous stem cell transplant.
M06	Annals: Dramatic recent rise in community-acquired MRSA infections.
M03	FDA issues additional warning on Prisma system and problem of excessive fluid removal.
F24	FDA approves new antifungal drug (Eraxis) effective against serious Candida infections.
F06	Rapid new test could cut MRSA risk.
F06	Synthetic heparin could replace animal-derived drug.
J26	Aprotinin (Trasylol) linked to increased risk of kidney failure, heart attack and stroke.
J25	32% of Americans carry S. aureus in their noses, and 1% (2 million) carry MRSA.
J23	Annals: Liver failure and hepatitis from telithromycin.
J21	FDA announces new program to monitor safety of medical devices.
J19	Study of drug resistance among bacteria found in soil can potentially guide new drug development.
J18	Helicobacter pylori becoming drug resistant - sequential therapy may do a better job.
J15	Acetazolamide reduces sleep apnea severity in heart failure patients.
J15	Thiamin deficiency common in hospitalized heart failure patients
J09	U.S. FDA sends Gambro a warning over Prisma machines manufactured in Italy.
J07	CJASN: Diagnostic and Therapeutic Corner: HAART and the Kidney
J07	CJASN CPC (full text): A 42 year old man with oliguric renal failure.
J05	MRSA patterns in ICUs changing: 64% prevalence rate, hardier, bugs, but less multi-drug resistance.
D28	Saliva test for hepatitis C developed by Israeli scientists.
D27	Acute renal failure due to phosphate-based colonoscopy preps.
D27	Acetaminophen can cause acute liver failure when usual dose is even slightly exceeded.
D26	Need a used medical device? Try Ebay.
D26	MMWR: Outbreaks of E. coli O157:H7 associated with petting zoos.
D26	Dalbavancin (a vancomycin-like drug) effective in mice against anthrax.
D23	Aspergillus fumigatus genome sequenced.
D21	New study says that two million Americans are nasal carriers of MRSA.
D17	Heteropolymer antibodies - a new approach to treat and prevent? MRSA infections.
D16	Mitochondrial gene haplotype has marked effect on survival after infection.
D12	Oral endothelial receptor antagonist ambrisentan effective in pulmonary HTN.
D12	AMG531 (Amgen drug) increases platelet count in patients with ITP.
D06	Annals paper shows that plasma exchange does not help in ARF due to MM.
D05	Coffee intake may reduce risk of liver damage.
D03	New CPR device improves blood return to the heart.
D03	Random testing shows high lead levels in some imported Chinese plums.
D01	Coffee and tea associated with lower risk of chronic liver disease.
N30	Study of ICU ultrafiltration with CHF solutions device published in the JACC.
N29