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HDCN News Archive -- Nephritis |
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| May29 |
Three days of fasting every 10 days improve autoimmune diseases (in mice). |
| Dec14 |
Even more news on the new HDCN Facebook page! |
| Nov30 |
Multinucleated giant cells and amyloidosis |
| Nov22 |
Renal pathologists soon will be replaced by pigeons. |
| Nov21 |
Orphan drug designation may lead to high drug prices, like for rituximab. |
| May30 |
Vagal nerve stimulation lowers inflammatory response in rheumatoid arthritis |
| May27 |
Binding site for PLA2R antibodies identified and blocking molecules synthesized |
| Nov18 |
Abatacept slows or halts proteinuria in FSGS. |
| Sep18 |
Vaccinating cattle against toxigenic E. Coli could cut risk of infection in humans. |
| Apr05 |
Malic acid mouth spay for xerostomia. |
| Mar07 |
High salt diet linked to activation of Th-17 helper cells and multiple sclerosis in mice. |
| Dec10 |
Reprogrammed T-cells using an attenuated strain of HIV result in remission of acute lymphoblastic leukemia. |
| Nov19 |
Nanotechnology cures multiple sclerosis in mice; are other autoimmune diseases next? |
| Nov05 |
Eculizumab for atypical HUS shows promise on longer term treatment. |
| Oct19 |
Egg freezing works to preserve fertility. |
| Oct17 |
Vitamin D supplements may benefit lupus patients |
| Oct05 |
Eggs made from skin cells fertilized with male mouse sperm and give rise to seemingly normal mice. |
| Sep19 |
What's causing an epidemic of tubulointerstitial nephritis in Uddanam, India? |
| Sep07 |
Anti-PLA2R antibodies detected in 70% of patients with idiopathic membranous GN |
| Jul21 |
JASN early release: Rituximab shows good results in membranous nephropathy. |
| Jul05 |
Origin of follicular dendritic cells found. |
| May29 |
KDIGO publishes 2012 practice guidelines for treating glomerulonephritis. |
| May22 |
Abacavir side effects linked to autoimmune reaction. |
| May19 |
Mouse study suggests benefits of scheduled eating. |
| May10 |
More severe scleroderma in African Americans linked to certain antibodies. |
| May04 |
Two types of macrophage cell lines identified. |
| May04 |
American College of Rheumatology issues lupus nephritis guidelines. |
| May04 |
Cardiovascular risks of varenicline not confirmed. |
| Apr17 |
Caffeine use may help dry eye syndrome. |
| Mar13 |
Shiga-toxin E. Coli carrier state markedly reduced by azithromycin treatment. |
| Mar13 |
Shiga-toxin producing E. Coli associated with correctional facility-run dairy. |
| Mar08 |
Donor stem cell transfusion helps achieve tolerance in the recipient. |
| Mar08 |
Silver mouthwash to treat oral Candidiasis. |
| Mar08 |
Scientist make revolutionary progress in electron microscope resolution. |
| Feb26 |
How vitamin D inhibits inflammation |
| Feb14 |
Amino acid response pathway, autoimmune disease, tolerance, and a Chinese herb. |
| Feb14 |
CYBORD multiple chemotherapy regimen (using bortezomib) good for AL amyoidosis. |
| Jan13 |
NIH study shows that 32 million Americans harbor autoantibodies. |
| Dec20 |
Eculizumab for toxigenic E. Coli- related illness. |
| Dec20 |
Cryptochromes interact with glucocorticoids to regulate metabolic processes. |
| Dec13 |
B-cells that are active only in the gut, turning into monocyte-like cells there. |
| Dec13 |
Sugarcane nephropathy afflicts many, but cause remains a mystery. |
| Nov09 |
Most women with lupus can have successful pregnancy outcomes |
| Oct14 |
ASN Renal Week 2011 abstracts now available. |
| Oct04 |
Scrub your potatoes and leeks to reduce the risk of toxigenic E. Coli. |
| Oct04 |
Vitamin D deficiency common in patients taking oral steroids. |
| Oct04 |
Gut protein alphavbeta6 may be key to developing immune tolerance |
| Sep27 |
Eculizumab approved by FDA to treat atypical hemolytic uremic syndrome. |
| Sep21 |
Continued immunosuppressant treatment of lupus in ESRD may boost survival. |
| Sep13 |
Fish oil reduces the effectiveness of chemotherapy. |
| Jul25 |
New relationships between germinal centers and regulatory T cells identified. |
| Jul23 |
Early intravenous fluid therapy may reduce risk of kidney damage after toxigenic E. coli infection. |
| Jun28 |
New genetic risk factors for lupus found in African Americans. |
| Jun07 |
Number of non O157 E. Coli cases causing HUS rising in the United States. |
| May31 |
Swedish gene analysis shows that venous thromboembolism has a hereditary component. |
| May31 |
NEJM: Eculizumab of benefit in children suffering from hemolytic uremic syndrome due to toxigenic E. Coli. |
| May10 |
Lund University researchers develop new test to diagnose lupus. |
| Apr28 |
Leprosy in the United States via transmission from armadillos. |
| Apr19 |
TH17 blocking drug halts multiple sclerosis in animal models, may also affect lupus. |
| Feb16 |
NEJM: HLA allele linked to idiopathic membranous nephropathy.. |
| Feb04 |
Defect in CD8 regulatory T cells linked to lupus in a mouse model. |
| Jan27 |
Could the predilection for autoimmune diseases among women be due to avoidance of dirt? |
| Jan15 |
National Library of Medicine's Daily Med website for quick access to drug package inserts. |
| Dec13 |
Lenalidomide boosts immunity in the elderly. |
| Nov16 |
FDA panel recommends approval of Benlysta to treat lupus flares. |
| Nov04 |
A traitor in our midst - the FAP-expressing immune cell protects cancer cells, allowing them to grow. |
| Oct18 |
Intestinal alkaline phosphatase (IAP) enzyme needed to maintain healthy bacteria in the gut. |
| Sep28 |
Abatacept found to be ineffective for lupus |
| Sep25 |
Octagam IVIG withdrawn from sale due to thromboembolic event risk. |
| Sep03 |
Mutation in toll-like receptor gene heightens lupus risk in men. |
| Aug29 |
Molecule found that deactivates selective components of the complement system. |
| Jul28 |
Presence of nonhuman sialic acid in biotech drugs can provoke an immune response. |
| Jul28 |
Pulse steroids kill plasmacytoid dendritic cells in lupus |
| Jul16 |
APOL1 gene increases risk of kidney disease in African Americans. |
| Jul15 |
NEJM: Rituximab may be better than cyclophosphamide for relapsing vasculitis |
| Jul15 |
NEJM: Rituximab similar to cyclophosphamide for treament of vasculitis. |
| Jul08 |
New mystery gene linked to FSGS |
| Jun17 |
Angiomyeloproliferative lesions in the kidney after direct autologous stem cell injection. |
| Jun17 |
Gut bacteria can clearly trigger arthritis in a susceptible-mouse model. |
| Jun10 |
Meta-analysis quantifies risk of nephrotic syndrome due to bevacizumab (2%). |
| Jun05 |
Baxter's IVIG Gammagard being withdrawn as a precaution due to allergic reactions. |
| Jun02 |
Activated basophils and IgE antibodies implicated in an animal model of lupus. |
| May04 |
Impaired function of natural killer T cells may contribute to pathogenesis of lupus and other autoimmune diseases |
| Apr30 |
Doxycyclin plus rifampin effective in Reiter's syndrome |
| Apr30 |
New gene link to scleroderma found |
| Apr28 |
Depomedrol and ACTH have different effects on osteonecrosis of the hip, VEGF. |
| Apr13 |
ITAM-coupled receptors linked to macrophage immune function, arthritis |
| Apr11 |
Nanovaccine stops type 1 diabetes from developing in mice. |
| Mar22 |
Effect of UV sunlight rays on multiple sclerosis -- something other than vitamin D at work? |
| Mar10 |
Hemolysis with intravenous immunoglobulin solutions |
| Jan29 |
Spontaneous remission in 34% of patient with idiopathic membranous GN treated conservatively. |
| Dec23 |
INF2 gene mutations linked to focal segmental glomerulosclerosis (FSGS) |
| Dec11 |
Blood stem cell transplants "cure" sickle cell disease in 9/10 adults |
| Dec04 |
Amyloid fibrils are toxic per se, the shorter the fibril, the more damage it causes. |
| Dec04 |
Observational study suggests remarkable protection against graft-versus-host disease by statins. |
| Dec03 |
Novel "locked nucleic acid" drug markedly lowers hepatitis C viral counts in chimpanzees. |
| Dec01 |
Are peptoids that disable autoreactive T cells the next step in treatment of autoimmune disease? |
| Nov26 |
Rituximab helps preserve beta cell function in patients with early type 1 diabetes. |
| Nov19 |
Cigarette smoke found to be contaminated with many pathogenic bacteria. |
| Nov06 |
1930s gonorrhea drug acriflavine blocks HIF-1 induced new blood vessel proliferation. |
| Nov05 |
Benlysta (belimumab) phase III trial for lupus gives positive results. |
| Oct29 |
Teriparatide outperforms alendronate in treating steroid-induced osteoporosis. |
| Oct28 |
Fish oil (DHA) metabolite resolvin 2 found to have marked anti-inflammatory activity |
| Oct28 |
Gut bacteria linked to diet, immune system functioning via short chain fatty acid receptor |
| Oct26 |
Histone released from damaged cells during trauma or sepsis damages blood vessels. |
| Oct23 |
FDA Medwatch reports another case of PML after rituximab in a rheumatoid arthritis patient. |
| Oct20 |
American College of Rheumatology 2009 annual meeting abstract search |
| Oct19 |
RItuximab as effective as cyclophosphamide in treating severe ANCA vasculitis. |
| Oct19 |
Gleevec for scleroderma |
| Oct19 |
Is lupus a garbage-disposal problem? And is PPAR delta an answer? |
| Oct15 |
Certain specific gut microorganisms induce the formation of Th17 immune helper T cells. |
| Sep24 |
AJKD issues containing KDOQI guidelines now freely available as .pdf files |
| Sep23 |
University of Michigan gets 10 million dollar grant to study nephrotic syndrome. |
| Sep14 |
Take a shower and get a faceful of Mycobacterium avium. |
| Aug28 |
Monoclonal gammopathy of undetermined significance found to be of undetermined significance. |
| Aug19 |
Vitamin D regulation of immune function via cathelicidin conserved in all primates. |
| Aug11 |
GIFT15 treatment modified B lymphocytes and reverses multiple sclerosis in the lab; may have potential in lupus as well. |
| Jul31 |
FDA warns of colchicine side effects when co-prescribed with clarithromycin and other drugs. |
| Jul31 |
Resveratrol found to have potent anti-infammatory effects. |
| Jul19 |
HGS/Glaxo drug Benlysta shows some effectiveness against lupus in phase 3 clinical trial. |
| Jul15 |
Bisphosphonates may lower mortality rate by an effect on the immune system. |
| Jul09 |
NOD2 receptor mutations impair ability to detect mycobacteria and are linked to Crohn's disease. |
| Jul02 |
NEJM: Phospholipase A2 receptor is a target antigen in 70% of patients with idiopathic membranous nephropathy. |
| Jun30 |
Key culprits in lupus (toll-like receptors) identified in mouse study. |
| Jun04 |
Halofuginone, Th17 cells, and autoimmunity. |
| May29 |
FDA: Serious fungal infections associated with TNF-alpha blockers. |
| May25 |
Search all abstracts from the World Congress of Nephrology 2009 |
| May22 |
New anti-inflammatory drug candidate works by releasing hydrogen sulfide gas. |
| Apr27 |
Potential importance of vitamin D receptor, commensal bacteria, and olmesartan in autoimmune disease. |
| Apr27 |
CXCR4 overproduction, kallikreins linked to lupus nephritis in 2 separate studies. |
| Apr22 |
Proton-pump inhibitors and NSAIDS have synergistic anti-inflammatory effects, and ? neuroprotective properties. |
| Apr18 |
Ultrashort-acting prednisolone derivatives (antedrugs) stop inflammation and then are metabolized to avoid side effects. |
| Apr16 |
JASN: Mycophenolate and cyclophosphamide similarly effective as induction therapy for lupus nephritis. |
| Apr11 |
One thousand 2007-2009 audiofiles and slide/audio talks added to HDCN's 20 topic-related channels. |
| A09 |
A contrarian view proposes that excessive 25-D supplementation might exacerbate autoimmune disease. |
| M30 |
New lupus susceptibility gene (IRAK1) on the X-chromosome may explain increased risk of lupus in women. |
| M29 |
Link to slide/audio and audio symposia on HDCN |
| M24 |
Licorice can block absorption of cyclosporin |
| M19 |
Small but randomized lupus trial suggests that both cyclophosphamide and cyclosporine are useful additions to prednisone. |
| M11 |
Rituximab study as adjunct to MMF in lupus nephritis shows disappointing results. |
| F27 |
FDA warns of tardive dyskinesia risk with Reglan (metoclopramide) |
| F15 |
FDA now requiring that each patient receiving CellCept (mycophenolate) receive a patient education guide. |
| F02 |
Leprosy drug clofazimine holds promise as an immunomodulatory agent. |
| J21 |
Interleukin-21 linked to lupus in an animal model. |
| J09 |
New drug combo (Mozobil, VEGF, GCSF) induces the body to release new types of autologous "healing?" stem cells into the blood. |
| J07 |
New Bartonella species that infects humans (muscle fatigue, weakness, pericarditis) discovered. |
| D27 |
Proteosome inhibitor and multiple myeloma drug bortezomib effective in reversing acute transplant rejection in a pilot study. |
| D22 |
Two percent of circulating B cells in normal subjects potentially have autoimmune activity but are shut off. |
| D11 |
CJASN: Rosiglitazone may benefit patient with FSGS |
| D04 |
HALT-C trial shows absolutely no impact of interferon on progression of hepatitis C |
| D03 |
Scientists film inner workings of the immune system sing multiphoton microscopy. |
| N27 |
JASN early release: Imatinib suppresses cryoglobulin production in mice. |
| N04 |
NK-22 cells - they're in the gut, they make IL-22, and are involved in mucosal immunity. |
| N04 |
1-alpha-25OH-D hydroxylase active in the lung; may be involved in immune defense. |
| N04 |
Strange, complex pharmacokinetics of methotrexate in RBCs have implications for clinical treatment. |
| O29 |
Patients with lupus being treated with hydroxychloroquine may have lower rate of kidney damage in observational study. |
| O23 |
European watchdog agency suggests not using diet drug rimonabant due to depression side effects. |
| O22 |
Low-levels of gut bacteria that secrete anti-inflammatory compounds may underlie or worsen Crohn's disease. |
| O17 |
New Mycobacterium species identified that can cause bone infections in the immunocompromised. |
| O07 |
NRAA: Advance copy of ESRD program interpretive guidelines. (pdf) |
| O07 |
Gut bacteria may protect mice against type 1 diabetes, other autoimmune disorders. |
| O03 |
DNA of commensal, good bacteria augment the intestinal response to infection. |
| S19 |
African American women have low white blood cell count. |
| S15 |
MYH9 gene variants linked to FSGS and diabetic kidney disease in African Americans. |
| S11 |
Rituximab prescribing info revised to reflect risk of progressive multifocal leukoencephalopathy. |
| S10 |
Molecular mechanism of steroid-induced fatty liver determined. |
| S05 |
FDA warns about invasive fungal lung infections in patients taking TNF-alpha blockers. |
| A25 |
Longer-term low-dose IL-2 treatment (metronomic dosing) has fewer side effects when used for prostate cancer. |
| A25 |
New guidelines to treat rheumatoid arthritis focus on disease-modifying drugs. |
| A25 |
FDA approves Nplate (romiplostim) to stimulate bone marrow in thrombocytopenia. |
| A24 |
Bifidobacterium infantis may have systemic immune system benefits. |
| A20 |
Individual genome analysis shows that drug sensitivity may be poorly predicted by skin color (presumed race) |
| A13 |
T-cell furin linked to autoimmunity |
| A06 |
NephCure announces recipients of research awards focusing on FSGS. |
| A06 |
November CJASN paper details benefits of rituximab in treating membranous nephropathy. |
| J30 |
Bifidobacterium infantis continues to show promise as treatment for irritable bowel syndrome. |
| J27 |
Human autoantibodies from women with pre-eclampsia induce the condition in pregnant mice. |
| J24 |
Complement activation is increased in patients with age-related macular degeneration. |
| J23 |
Scientists isolate compound in saliva that speeds wound healing. |
| J17 |
Peptidoglycans from gut bacteria may induce C. albicans to transform into infectious variant. |
| J16 |
Has the Achilles heel of the HIV virus been located? |
| J11 |
FDA lists May 2008 labeling changes: Aranesp (tumor progression) and CellCept (lymphoma and PML risk) |
| J10 |
Computational biology approach leads to better understanding of immune response to presented antigen. |
| J08 |
Farm-raised tilapia fish has relatively low levels of omega-3 fatty acids. |
| J30 |
Cancer cure strategy in mice to be tested in humans: transfusion of allogeneic cancer-killing leukocytes. |
| J28 |
FDA/Roche: Progressive multifocal leukoencephalopathy (PML) warnings added to mycophenolate labeling. |
| J25 |
Site indentified at which microRNAs may down-regulate immune response. |
| J18 |
Computer generated warfarin dosing as effective as dosing by expert prescribers. |
| J12 |
Sequential treatment of lupus in women with cyclophosphamide and mycophenolate preserves ovarian function. |
| J11 |
Lupus more severe, and nephritis more common, in patients with Southern European ancestry. |
| J09 |
Myeloma drug Velcade (bortezomib) shows promise in treating lupus in an animal model. |
| J05 |
FDA: More on the ongoing review of TNF-blockers and cancer risk. |
| J05 |
Alcohol ingestion cuts risk of rheumatoid arthritis by 50%. |
| J04 |
FDA reviewing reports of increased cancer risk associated with TNF- blocking drugs. |
| M19 |
A new discovery regarding pathogenesis of lupus - abnormal editing of genes. |
| M16 |
Heparin-coated thoracic drainage catheters being recalled because of OSCS contamination. |
| M15 |
University of New Hampshire group enhances the immunomodulatory effects of IVIG by modifying its sialic acid residues |
| M13 |
Texting kids to take their medicine may increase compliance. |
| M05 |
ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format. |
| A29 |
Rituxan fails as lupus treatment in controlled trial. |
| A29 |
Jund, a gene that regulates activity of macrophages, linked to kidney inflammation. |
| A24 |
GAO says that FDA lacks resources to inspect non-US drug suppliers; only 8% are being inspected now. |
| A12 |
Once yearly zoledronic acid increases lumbar spine density by 4% in glucocorticoid-induced osteoporosis patients; better than risedronate |
| A10 |
FDA communication regarding CellCept and Myfortic (mycophenolate) - ongoing safety review. |
| A10 |
FDA notice regarding investigation of mycophenolate mofetil regarding progressive multifocal leukoencephalopathy. |
| M31 |
Mysterious periodic fevers in children cured by tonsillectomy. |
| M19 |
New camera with multiple lenses will be able to take detailed 3-D photographs. |
| M12 |
New macrophage-related protein implicated in inflammatory disease. |
| M06 |
Lupus foundation sponsored webchat about lupus and kidney disease scheduled for Wednesday, March 14th. |
| F23 |
Making heparin is a dirty job |
| F12 |
Embryonic stem cells can be used to create fully functioning immune cells. |
| F11 |
Integrin receptor linked to HIV infection and replication in the gut. Is a treatment already available? |
| J21 |
Anti-TNF compounds as well as rituximab, disrupt lymph node germinal centers. |
| J20 |
NEJM: Association of Systemic Lupus Erythematosus with C8orf13-BLK and ITGAM-ITGAX |
| J20 |
Nature genetics: Abstract link for lupus consortium genome link study |
| J20 |
Nature genetics: International consortium identifies multiple genes linked to lupus in women. |
| J17 |
Scientists find new genetic mutation that halts development of lupus. |
| D21 |
Complement cascade blocker eculuzimab effective against myasthenia gravis in animal model. |
| D08 |
FDA launches new drug safety newsletter. Here is the first issue (rituximab) |
| D03 |
Pharma companies to develop IgA proteases as a potential treatment for IgA nephropathy. |
| D03 |
New lupus susceptibility gene discovered - OX40L |
| N28 |
American College of Rheumatology 2007 Annual Meeting - abstract search tool |
| N28 |
Valproic acid and mithramycin show activity against lupus in a mouse model. |
| N09 |
Valproic acid reduces proteinuria in a mouse model of lupus nephritis. |
| N07 |
New diagnostic test for TTP (thrombotic thrombocytopenic purpura) to be available via Ohio State University. |
| N07 |
Prazosin appears to block some glucocorticoid effects. |
| N05 |
Gene associated with rheumatoid arthritis identified on chromosome 6. |
| N02 |
NephroCor introduces enhanced urine analysis test (RenalVysion) for kidney disease |
| O26 |
Hidden value found in junk DNA |
| O09 |
Can we make a computational model of the immune system? One group is going to try. |
| S25 |
FDA Drug Safety Newsletter: Progressive multifocal leukoencephalopathy associated with rituximab. |
| S10 |
Aspreva and Roche decide not to pursue application to FDA for CellCept as induction treatment for lupus nephritis. |
| S06 |
International pathology conference solves shows high-detail microscopy slides on the web. |
| S06 |
Study identifies genetic risk factor (STAT4) for lupus and rheumatoid arthritis. |
| S05 |
Phospholipase C epsilon gene mutation affects podocytes, causes infantile nephrotic syndrome. |
| A06 |
JCI paper shows that cleavage of a protein called dynamin a key event in causing podocyte leakage of proteins. |
| J26 |
MMWR: Cryptosporidiosis outbreaks associated with recreational water use. |
| J23 |
Sialic acid may determine whether IgG antibodies are anti- or pro-inflammatory - link to autoimmune disease? |
| M11 |
Lupus cluster in people living above abandoned oilfield in New Mexico. |
| A10 |
FDA re-emphasizes Salmonella risks for people with impaired immune systems keeping pet turtles. |
| J22 |
New master gene that regulates autoimmunity and regulatory T cells identified. |
| D19 |
FDA warns about two cases of progressive multifocal leukoencephalopathy (PML) in lupus patients treated with rituximab. |
| D12 |
New EPO-like drug mimics action of thrombopoietin: designed to treat thrombocytopenia. |
| D11 |
FDA proposes rules overhaul to expand access to experimental drugs. |
| N26 |
HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts |
| N14 |
Lymphostat (belimumab) effective against lupus in paper presented at rheumatology meeting. |
| N07 |
Michigan researchers link gene mutation in phospholipase C epsilon to podocytes, infantile kidney failure. |
| O26 |
Phase 3 trial design for belimumab to treat SLE approved by FDA |
| S27 |
La Jolla Pharm announces addition of new sites, reactivation of Riquent (abetimus) study to treat lupus. |
| S26 |
Genetic variations in MHC (major histocompatibility locus) posted on-line, clues for transplant and immune diseases. |
| S14 |
Spleen may be target for successful therapy of lupus. |
| S06 |
Chronic sinusitis linked to immune response to parasites and chitinase enzyme levels |
| S04 |
Mutation affecting platelets gives clues about crescentic glomerulonephritis |
| A04 |
New research gives clues as to why IVIG works in autoimmune disease (sialic acid). |
| J19 |
New egg freezing technique may be of interest to patients undergoing cytotoxic therapy. |
| J16 |
CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!) |
| J16 |
Precise gene defects identified that cause lupus in mice. |
| J16 |
Rats that don't shower every day may be protected against autoimmune disease. |
| M24 |
Canadian scientists working to develop a synthetic replacement for IVIG |
| A27 |
Stem cells replace or fix podocytes damages in animal model of Alport syndrome |
| F26 |
Mystery solved: Gold's power against autoimmune diseases defined |
| F21 |
Is there a way to avoid the bladder toxicity of cyclophosphamide? |
| F12 |
Anti-malarial drugs lower elevated TNF-alpha levels in lupus patients. |
| F01 |
Stem cell transplants offer hope against lupus. |
| J28 |
Enhanced oocyte cryopreservation method (of interest to GN patients requiring cytotoxic therapy). |
| J19 |
Commonly used antidepressants may also affect the immune system. |
| J11 |
Infection fighting protein (cryopyrin) may be key to auto-immune disease. |
| D06 |
Annals paper shows that plasma exchange does not help in ARF due to MM. |
| N23 |
US RCT shows mycophenolate better than cyclophosphamide to remit lupus nephritis |
| N17 |
Genetic profiling identifies 10 genes linked to severity of lupus. |
| N17 |
Canadian study suggests that drinking too much water can harm kidneys. |
| N16 |
Trichostatin may reduce premature atherosclerosis in lupus patients. |
| N16 |
High HDL level is pro-atherosclerotic in lupus patients. |
| N08 |
Protein discovered that is key to survival of E. coli O157:H7 |
| N07 |
Are epigenetic changes in histones the key to lupus autoimmunity? |
| N07 |
Parasitic worms may hold key to immunosuppression. |
| O26 |
ASN Renal Week 2005 abstracts now available on-line. |
| O17 |
Smoking ups risk of thrombosis in lupus patients. |
| O16 |
Novel DnaJP1 rheumatoid arthritis drug works without being immunosuppressive. |
| O12 |
CD19 monoclonal antibodies suppress B cells better than rituximab. |
| O12 |
New immunosuppression strategy has little weight, and in fact is in outer space. |
| O09 |
SEPS 1 gene on chromosome 15 plays key role in inflammation. |
| O07 |
Study of tonsillar lymph cells highlights role of autoreactive B cells in lupus. |
| O05 |
Human Genome's experimental lupus drug Lymphostat-B fails to meet goals. |
| O03 |
THi cells make IL-17 and may be key to some autoimmune diseases. |
| S27 |
Baxter announces new IVIG (intravenous immune globulin) product. |
| S21 |
O-GlcNac sugars, rather than cyclins, prime determinants of cell cycle control. |
| J10 |
Gene for immune deficiency syndromes found. |
| J08 |
Genomic mechanism of increased azathioprine toxicity identified. |
| J04 |
How cells with damaged DNA alert the immune system |
| J10 |
Researchers get first peek at amyoid structure. |
| J07 |
New methods may preserve fertility in girls receiving cytotoxic therapy. |
| J06 |
Fibrillex retards CKD progression in AA amyloidosis. |
| M30 |
Workplace solvent TCE linked to immune system disorders. |
| M30 |
Freezing eggs before chemotherapy in women to preserve fertility. |
| M28 |
Long-term effects of Canadian toxigenic E. Coli outbreak in the news. |
| M07 |
Immune gene with 20% prevalence linked to CAD, rheumatism, and MS. |
| M06 |
Nephrogenex licenses kidney disease molecular profiling technology. |
| M06 |
Novel cation transport gene linked to inherited form of FSGS. |
| M03 |
Schelling paper that is the basis for the dipstick protein-SC calculator |
| M01 |
Lupus in Native Americans from New Mexico often involves the kidneys. |
| A16 |
Lupus Research Institute launches awareness campaign with actor James Garner. |
| A09 |
CD36 may be a key component of innate immunity |
| A07 |
Lupus linked to Epstein-Barr virus IgA antibodies in Blacks. |
| M14 |
La Jolla lupus drug on track, but off the fast track in terms of FDA approval. |
| M02 |
Lupus Research Institute funds innovative research - get grant application. |
| F02 |
Lupus Research Institute increases funding for innovative research. |
| D02 |
Eating red meat associated with increased risk of rheumatoid arthritis. |
| N20 |
Another lupus drug in the pipeline - favorable animal studies |
| N11 |
Curagen working on monoclonal antibody treatment for IGAN |
| N07 |
North Carolina E. Coli outbreak grows, linked to State Fair, petting zoo |
| N05 |
Scientists identify new biomarkers for lupus |
| O30 |
ASN: Riquent lowers dsDNA levels in lupus patients as adjuvant therapy |
| O18 |
Mycophenolate effective to treat non-renal lupus |
| O18 |
Experimental lupus drug may also work against atherosclerosis |
| O15 |
La Jolla Pharma's FDA approval for lupus drug delayed: another RCT required |
| S24 |
Woman gives birth: Ovarian tissue frozen 7 years, reimplanted after chemoRx |
| S17 |
Urinary MCP-1 to follow the course of renal vasculitis |
| S16 |
Rituximab shows promise against lupus |
| S09 |
Prasterone (DHEA) effective as adjunctive Rx for lupus in RCT |
| S08 |
Cancer drug may reduce kidney disease in lupus |
| A29 |
A20 anti-inflammatory enzyme may prove to be a potent drug target |
| A26 |
NEJM: Bones OK in kids after steroid treatment of nephrotic syndrome |
| A23 |
IGF-1 receptor activation implicated in rheumatoid arthritis and autoimmunity |
| A18 |
Gene associated with lupus identified |
| A17 |
Group A streptococcus vaccine promising in early trials |
| A09 |
MMWR: Tuberculosis associated with TNF-alpha blocking drugs |
| J09 |
Lack of immune system protein prevents lupus-like condition in mice |
| J24 |
NEJM: Kidney disease no longer a killer for children |
| M15 |
NIH launches stem cell transplantation for lupus clinical trial |
| A06 |
Alliance for lupus research announces 6.7 M grant recipients |
| M03 |
Use of CYC + MMF or AZA for lupus published in
NEJM |
| F24 |
Isotope studies quantify water intake in normal people - averages 2.5-3.0 L/day |
| F23 |
c-maf oncogene elevated in half of multiple myeloma cases |
| F21 |
CellCept for lupus in the news |
| J27 |
Cystic fibrosis protein CFTR shown to have adenylate kinase activity |
| J22 |
First int. symposium on albuminuria (NKF-ISN) to be held in New York in May 2004 |
| J08 |
Anti-eosinophil therapy shown effective in treating hypereosinophilic syndrome |
| D16 |
La Jolla Pharmaceutical submits new drug application for anti-lupus compound |
| D10 |
Press reporting on MMF lupus study results from SUNY |
| D04 |
Multiple myeloma causing progenitor stem cell identified |
| D03 |
E. Coli O157 apparently spread by sawdust from exhibition hall rafters |
| D02 |
Revimid, a thalidomide derivative, may benefit multiple myeloma patients (PDF) |
| N11 |
Apoptosis of endothelial cells linked to heart risk in lupus patients |
| N01 |
Sulfatides (present on blood cells) are target for antiphospholipid antibodies |
| O28 |
TNF alpha linked to photosensitivity in lupus |
| O25 |
Mycophenolate trial results for lupus reported at Am Coll Rheumatology meeting |
| O22 |
Living with lupus: one patient's story |
| O22 |
Lactobacillus - vaccine combination lowers toxigenic E. Coli prevalence in cows |
| O15 |
NEJM: Autoantibodies in soldiers years before clinical onset of lupus |
| O06 |
NJ basketball star with FSGS on the rebound |
| S18 |
Cranberry juice may increase bleeding risk with warfarin |
| S08 |
Genetic approaches seek to eliminate O157 E. Coli gut colonization of cattle |
| S08 |
Vaccine against autoimmune disease to be tested |
| A25 |
Lupus Foundation of America to launch new patient-oriented magazine |
| A23 |
Lactoferrin spray on meat considered safe to fight E. Coli |
| A17 |
Philly petting zoo closed temporarily: possible source for toxigenic E. Coli |
| J29 |
O157:H7 antibody trial for HUS underway in Canada |
| J18 |
PPAR-alpha linked to steroid-induced diabetes and hypertension |
| J05 |
Argentina shuts McDonald, Burger King restaurants because of E. Coli fears |
| J04 |
Toxigenic E.Coli infected teens attending prom at Mississauga, Ontario |
| J03 |
ECSYSVAS: Cyclophosphamide can be replaced with azathioprine after remission |
| J25 |
NEJM: Bortezomib benefits a third of multiple myeloma patients |
| J14 |
How antibiotic therapy can worsen or cause HUS |
| J04 |
Hemolytic uremic syndrome tragic patient stories in the news |
| J02 |
Gene defect produces lupus-like disorder |
| M24 |
Phage transfer implicated in toxin-producing bacterial infections |
| M13 |
FDA approves proteasome inhibitor drug Velcade for multiple myeloma |
| M06 |
Staph aureus effect on B cells might be useful to treat lupus |
| A25 |
Bacteriophage approach can kill E. Coli, possibly also O157:H7 |
| A12 |
Should we routinely text the urine for microhematuria? |
| A11 |
Athlete sues NSAID maker, claiming NSAIDs cause his proteinuria |
| M24 |
High-dose steroids linked to cardiovascular disease |
| M11 |
Fish oil may benefit lupus patients |
| F18 |
La Jolla Pharmaceutical lupus drug (Riquent) fails key test; stock plummets |
| F15 |
Trichostatin ameliorates lupus expression in mice |
| F12 |
Interferon genes linked to lupus in NIH study |
| F10 |
RNA interference halts hepatitis in mice |
| F10 |
RNA interference halts hepatitis in mice |
| J22 |
Rapamycin may be useful against lupus |
| J18 |
Amgen says Enbrel works against psoriasis in study |
| J14 |
Abbott enters TNF blocker fray with Humira |
| J10 |
High-dose cyclophosphamide regimen for lupus patients |
| N07 |
View abstracts from Am Coll Rheumatol Annual Meeting |