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Achieving Control: Optimizing the Management of CKD-Anemia
Flash slide/audio
(CME Symposium (Synermed-Penn State), March, 2008)
Nissenson: What is the difference between target and achieved hemoglobin? What did the 2007 KDOQI anemia update recommend and what were the results of the KDOQI meta-analysis?
Fishbane: In CKD, at what point should one start to treat a low Hb? What is the approach to ESA hyporesponsiveness? How can one dose iron and ESA in such a way to limit Hb variability? Why
is Hb variability relevant?
Germain: What are the various drugs available to stimulate red cell production? What are their pharmacokinetics? To what extent is pharmacologic half-life associated with the time course of
Hb response, especially with less frequent dosing? Is Hb variability different with shorter and longer half-life drugs? How frequently should Hb be monitored? What are good strategies for ESA dosing
adjustment?
Provenzano: What are areas were care of predialysis CKD patients might be improved? What resources do such patients utilize? What is the cost of providing care to them? What is the
opportunity for providing care to this population and maintain reimbursement to have a viable practice? What is the RPA CKD management toolkit, and how can it help in the care of these patients? What
are services, revenue, and costs of a CKD clinic model?
(more...)
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Mycophenolate in Lupus and Non-Glomerular Renal Diseases
Flash slide/audio
(ASN Clinical Nephrology Conference, November, 2007)
Shaw: How is MMF metabolized? How is MPA excreted? Why is enterhepatic circulation of MPA glucuronide important, and how is it affected by intestinal bacteria and cyclosporine? What does the
new MPA assay measure? What are provisional guidelines for trough levels of MPA and area under the curve for MPA in transplantation?
Appel: How does ethnicity affect response of lupus nephritis to treatment? What did the major trials show in terms of MMF use for maintenance treatment of lupus nephritis as well as for
induction treatment? What are the options for use of MMF with additional immunosuppressive drugs?
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ASDIN Annual Meeting. February, 2008. Part One.
Flash slide/audio -- Free to ASDIN members
Vessel Mapping
Linda Francisco,M.D.
Approach in Difficult Patient: Mastectomy, Stroke Arm etc
Naveen Atray, MD, FASN.
Forearm AVG Before Upper Arm AVF
Naveen Atray, MD, FASN.
New AVG materials - Update and endovascular approach
Surendra Shenoy M.D., Ph.D.
Stent Placement
Timothy A. Pflederer, MD.
Physical Examination
Arif Asif, M.D.
(more...)
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RPA Annual Meeting. March, 2008. Part Two.
Flash slide/audio -- Free to RPA members
Louis Diamond Lecture: Is Decision Support Software Worth the Investment?
Mark Graber, MD
Good Medical Practice-USA: Establishing Physician Competency
David Watt, MD, PhD, MPA
The Janus Face of Close Partnership with Industry
Nathan Levin, MD
Clear Separation will lead to best care for patients
Jonathan Himmelfarb, MD
Herding Cats: How to Manage Physicians' Teamwork
Susan Diamond, MD
(more...)
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RRI Tenth International Conference on Dialysis, January, 2008. Part Four
Flash slide/audio
(Renal Research Institute, January, 2008)
Debate Part I - Guidelines have improved patient care and outcomes
Adeera Levin, MD
Debate Part II - Guidelines have done more harm than good
Richard Amerling, MD
Uremic toxins: do we know enough to explain uremia?
Raymond C. Vanholder, MD, PhD
How do various aspects of body composition seriously affect dialysis outcomes?
Peter Kotanko, MD
International differences in presentation, prevention and management of CKD in Eastern Europe
Boleslaw Rutkowski, MD, PhD
International differences in presentation, prevention and management of CKD in Latin America
Ricardo Correa-Rotter, MD
(more...)
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ASN Renal Week 2007
now in MP3
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AUDIOFILE
LIST (Renal Week 2007)
2007 Renal Week PGE Course:
KIDNEY TRANSPLANTATION FOR THE GENERAL NEPHROLOGIST (Part 1 of 2)
How the Immune System Recognizes an Allograft?
Milagros D. Samaniego-Picota, MD, FASN
Immunological Assessment of the Transplant Patient
Douglas J. Norman, MD
Organ Allocation Within the USA
Winfred W. Williams, MD
Options for the Sensitized Patient
Stanley C. Jordan, MD
Recipient Evaluation
David J. Cohen, MD
Living Donor Evaluation
Connie L. Davis, MD
The Pathology of Acute Allograft Dysfunction
Cynthia C. Nast, MD
Immunosuppression Trends in Transplantation
Robert S. Gaston, MD
Options for the Diabetic Renal Transplant Recipient
Martha Pavlakis, MD
Post Transplant Diabetes Mellitus
Fernando G. Cosio, MD, FASN
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Hypertension, Cardiovascular:
None this week
Dialysis, ESRD:
Weight loss after surgery and proteinuria; Affordable water management practices in dialysis; Baseline inflammation, catheter use, and mortality; High ID weight gain lowers survival; Body temperature
and survival; Pi kinetics in 3x/week nocturnal HD; Peritonectomy for peritoneal sclerosis; Hispanic survival; Care of undocumented ESRD patients; Adipose tissue responsible for insulin resistance in
CKD; Heme iron polypeptide; More proteinuria with iron sucrose than gluconate; Ferumoxytol early results; FG4592 early results (prolyl hydroxylase inhibitor); Mild anemia means frailty in elderly
women with CKD; IV vitamin D and hospitalization risk; 25D deficiency correction improves muscular function; In vivo KoA-Calcium for dialyzers; Serum Pi and coronary calcification; Fractional Pi
excretionand CAC; Pi burden higher in PD than HD; Sodium thiosulfate prevents CAC in rats; High glucose downregulates 1-alpha-hydroxylase (D3); Early IV calcitriol inhibits PTH growth; Brazilians have
low 25D levels after winter; 25D deficiency common in Southern USA; Cinacalcet in severe secondary HPTH; Rise in FGF-23 in early CKD; Calcidiol synthesis lower in uremic rats; New class of vitamin D
analogs; Cinacalcet plus D vs. D alone; Risk of NSF low with gadoteridol; Kidney disease with rheumatoid arthritis.
Clinical Nephrology:
Treatment guidelines lower risk of ESRD in idiopathic membranous.
(more...)
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Staging of chronic kidney disease: time for a course correction
Bauer et al tell us why the NKF KDOQI staging system is seriously flawed;
from the May issue of
the J Am Soc Nephrol (JASN)
(more...) |
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Idiopathic membranous nephropathy: diagnosis and treatment
Fervenza and colleagues review the latest approach to idiopathic membranous nephropathy;
from the May issue of the Clinical J Am Soc Nephrol (CJASN)
(more...) |
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High-molecular weight iron dextran: a wolf in sheep's clothing?
Rodgers et al describe patient allergic reactions in patients switched from low to higher MW dextrans by the pharmacy in order to save costs.
from the May issue of
the J Am Soc Nephrol (JASN)
(more...) |
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Nephrogenic systemic fibrosis: early recognition and treatment
Knopp and Cowper review the very early signs of this disorder, and discuss criteria for diagnosis as well as etiology.
from the April issue of Seminars in Dialysis.
(more...) |
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Glucose in the dialysate: Historical perspective and possible implications?
Sharma and Rosner discuss this. Should we add glucose at all? If so, how much is too much, and how much is enough?
from the April issue of Hemodialysis International.
(more...) |
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Atherosclerotic renal artery stenosis: overtreated but underrated?
Textor reviews the latest in terms of diagnosis and treatment; this test;
from the April issue of
the J Am Soc Nephrol (JASN)
(more...) |
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Trends in organ donation and transplantation in the United States, 1997-2006
Port and his colleagues document the trends in organ transplantation and transplantation up through 2006;
in the April 2008 issue of the
Am J Transplant.
(more...) |
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Revisiting the dialysate sodium prescription as a tool for better blood pressure and interdialytic weight gain management in hemodialysis patients.
Santos and Peixoto review the current recommendations for optimizing dialysate sodium level in dialysis patients;
from the March issue of the Clinical J Am Soc Nephrol (CJASN)
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The utility of the transtubular potassium gradient in the evaluation of hyperkalemia
Choi and Ziyadeh review how the TTKG can be used to distinguish etiology of hyperkalemia, and discuss the pitfalls and shortcomings of this test;
from the March issue of
the J Am Soc Nephrol (JASN)
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Beta-blockade in chronic dialysis patients
Furgeson and Chonchol review the data of benefit, and also point out the potential risks of using them in CKD;
in the Jan/Feb issue of Seminars in Dialysis.
(more...) |
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Transplant glomerulopathy
Cosio et al present evidence that transplant glomerulopathy (TG) may be a distinct entity. Onset may be early, progression insidious. It is associated with HLA Class II antibodies.
Therapy for this progressive condition is not yet well worked out;
in the March 2008 issue of the
Am J Transplant.
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Poor correlation between coronary artery calcification and obstructive coronary artery disease in an end-stage renal disease patient.
Ton, Mehrotra, and their colleagues look at calcification and atherosclerosis and find one patient where lots of calcium did not mean obstructive coronary disease.
from the January issue of Hemodialysis International.
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Cerebral salt wasting vs. SIADH
Sterns and Silver argue that maybe we can't tell them apart and maybe we don't even need to be able to do this;
from the February issue of
the J Am Soc Nephrol (JASN)
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Mechanisms of vascular calcification in chronic kidney disease
Moe and Chen discuss the complexities of VSMCs thinking that they are osteoblasts;
from the February issue of
the J Am Soc Nephrol (JASN)
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Battleground: chronic kidney disorders mineral and bone disease - calcium obsession, vitamin F, and binder confusion
Kovesdy, Mehrotra, and Kalantar-Zadeh present a skeptical view of many truisms in the mineral bone disorder of CKD, and discuss where answers may be counter-intuitive; from the January issue of
the Clinical J Am Soc Nephrol (CJASN)
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Alcohol intake ups metabolic syndrome
