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HDCN News Archive -- Chronic Kidney Disease
J23 NEJM: Genetic mutation associated with most patients who develop myopathy on high-dose statins.
J17 Radiocontrast nephropathy studies may overestimate risk of AKI, since creatinine often increases in controls patients, also.
J14 CKD screening shows that a high percentage of Australia's indigenous population has kidney disease.
J03 Secondary analysis of CHOIR data suggests that high EPO doses, rather than high Hb per se, associated with mortality.
J19 Is fluoride in drinking water safe for patients with CKD?
J10 Large Australian RCT specifically shows that lowering HbA1C in diabetics to a 6.5% target protects the kidney.
J05 NEJM: Aliskiren plus losartan lowers proteinuria in diabetics.
M12 Should the NKF KDOQI staging system for CKD be modified?
M07 JASN: Calcitriol associated with a lower mortality in pre-ESRD patients.
M05 ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format.
A09 NEJM: ACEI = ARB, and ACEI + ARB no better than either ACEI or ARB, in high risk patients with diabetes or vascular disease.
M20 JASN Express: Remission clinic targetting proteinuria with multidrug therapy markedly slows rate of CKD progression.
M06 7th Annual Prevention in Renal Disease Conference, Toronto, Sept. 19-20, 2008.
M01 Screening test for CKD (SCORED) developed by Cornell and UNC Chapel Hill outperforms NKF KEEP approach.
F26 Diazyme introduces new assay for cystatin C.
F21 Study suggests that Medicare part D patients use more cardioprotective drugs after MI and live longer.
F13 University of Groningen study (PREVEND) emphasizes utility of treating hypertension in proteinuric patients.
J24 Researchers cast doubt on UK's universal screening program for CKD.
J18 Canadian study suggests drinking 4 liters of water per day can cause proteinuria; reversible when water ingestion reduced.
O12 FDA advisory meeting next Tuesday to study use of phosphate binders in pre-ESRD - Genzyme, Shire, Fresenius will all be present.
S12 JAMA paper shows no benefit of lowering homocysteine in CKD
J16 Kibow to test probiotic in stage III and IV CKD
M02 Editorial review of Brunori et al paper: (Late start dialysis in the elderly)
M02 Early start? How about very late start in patients over 70 with very low protein diet?
M03 MMWR reports on NHANES survey and CKD; prevalence appears to be increasing.
F08 Rate of CKD due to type 2 diabetes soaring in Canada.
F01 Biotrends report of Dec 2006 survey on use of ESAs and phosphate binders.
D02 India's Society of Nephrology prepares first report on CKD in India - socioeconomic problems highlighted.
N26 HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts
N16 Reanalysis of TNT study presented at AHA: Suggests high-dose atorvastatin lowers stroke, CV risk in CKD patients.
N14 National Kidney Foundation launches new phase of KEEP - to help patients in early stages of CKD.
O18 NABI announces positive results from PhosLo in stage 4 CKD
O18 Cockcroft Gault equation (modified) better than MDRD for adjusting vancomycin dose in the elderly.
S18 Low blood levels previously thought to be safe linked to risk of CV death
S11 NKDEP program to standardize serum creatinine measurements
S11 NKDEP GFR estimation summary
A25 NKDEP launches creatinine standardization program
J31 Primary care doctors failing to diagnose and refer chronic kidney disease
J16 CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!)
J08 Is the Mayo Clinic GFR estimating equation better than MDRD for predicting CV risk?
M26 Art Buchwald is still alive - a testimony to conservative management
M12 JASN paper: Obesity triples risk of CKD (pdf)
M13 High-dose atorvastatin (Lipitor) improves kidney function in CKD patients in large clinical trial.
F26 New Zealand kidney foundation launches a campaign for people to drink water vs. soft drinks.
F06 Survey of UK dialysis units focuses on late referral, AV fistula use, MRSA.
J02 UCSF study in Annals suggests that obesity increases risk of kidney failure.
D15 Bifidobacterium infantis now available for IBS: Does it benefit ESRD pts?
D15 Both BNP and NT-proBNP useful to deteck CHF in persons with CKD.
D05 Sally Burrows-Hudson, RN to head up business development for CORA.
N16 Pioglitazone reduces heart attack rate in type 2 diabetics by 28%.
N13 ASN: Sulodexide phase 2 trial shows good results in diabetic nephropathy.
N05 MMWR: Progression in diabetics stabilizing or slowing in recent years.
N02 JASN: USRDS predicts 713,000 prevalent ESRD patients by 2015.
O31 Dialysis patients often have family members who are also on dialysis.
O27 Roche suspends Tamiflu shipments to the U.S.
O27 JASN Express: Pravastatin lowers CV death risk in diabetics with CKD.
O26 ASN Renal Week 2005 abstracts now available on-line.
O12 JAMA: ESRD incidence, prognosis improving in diabetics.
O11 USRDS: US rates of kidney failure stabilize, ending a 20-year climb!
O09 JASN: Glycosylated Hb in non-diabetic CKD pts. increases mortality risk.
S09 Spironolactone added to ACEI/ARB gives added renoprotection in diabetics.
A16 Analgesic drug use linked to high blood pressure in women.
A03 JASN articles focuses on poor medical care received by CKD patients.
J28 JASN: ADMA strongly predictive of CKD progression
J23 UK CKD guidelines
J22 CDC reports less lead, cotinine in U.S. population; cadmium still of concern.
J08 Illinois Public Health directed by governor to establish CKD detection program.
J08 Ruboxistaurin lowers proteinuria in diabetic GN by 24%.
J07 Nephroprevention Conference 2005 to be held in Toronto, Sept. 23-24.
J28 Benign prostatic hypertrophy associated with increased CKD risk in Mayo study.
J23 Vitamin D deficiency in CKD - why should we care?
J17 High levels of ADMA associated with renal disease progression in CKD.
J16 Lead exposure from using indoor firing ranges by shooting teams.
J16 APOE allele may slightly increase risk of CKD.
J13 Incidence of diabetes in U.S. ESRD patients falls by 30%
M18 NEJM: Cystatin levels predict mortality better than Scr in the elderly..
M09 Moderate alcohol consumption helps maintain GFR over time.
M03 Consumer Reports website suggest Best Buys for ACE inhibitors.
M03 Schelling paper that is the basis for the dipstick protein-SC calculator
M03 Schelling-Case Western dipstick proteinuria/specific gravity calculator.
A27 Louisiana, Mississippi, Tennessee top 3 states in terms of CKD risk.
A08 New kidney protein 'renalase' - regulates heart contraction and blood pressure
M29 New protein identified (KCP) that protects kidneys against injury/progression.
J15 AAKP educational conference series for patients with CKD
D28 NIH, JDRF, CDC announce new genetic data bank for diabetic kidney disease.
N26 Epidemiologic study links high water intake to proteinuria.
O26 KDIGO.org website now up for international kidney disease guidelines
O14 U.S. NKF announces availability of nephrologist toolkit for CKD
O07 MMWR; United States CKD prevalence rates double from 1990-2001.
S24 Even mild kidney disease raises risk of heart disease and death
S15 Concern over children's exposure to lead in the U.K.
J29 Smoking increases CKD risk by 50%
J26 Long-term acetaminophen use may harm kidneys
J15 New NIH initiative aims to reduce kidney failure in African Americans
M01 Taiwan tops the world in percentage of dialysis patients
J23 Prevention in Renal Disease: 3rd Annual Conference in Toronto, Oct 1-2, 2004
D14 New Medicare law gives boost to disease management programs
N20 NKF screens 10,000th patient in Washington DC area for CKD
N17 Kidney failure linked to patients with severe gout and uromodulin gene defect
N15 ASN: Heavy use of aspirin or acetaminophen associated with ESRD
N14 Baxter announces launch of CKD research program
S09 Smoking reduces monamine oxidase levels in the kidney and other organs
J17 NKF CKD guideline summary published in Annals
J27 Bone morphogenic protein (BMP-7) slows scarring, progression in mouse CKD
J12 NIH Chronic Renal Insufficiency Cohort (CRIC) study begins to enroll patients
M29 Athlete sues university, doctors, for failing to predict kidney failure
M23 Gene that helps kidneys eliminate protein linked to progression
A25 Mechanism of adverse effect of a high-protein diet on the kidney proposed
F11 UK dialysis resources being strained by increased patient load
J26 Gates foundation offers 200 M for research in global health
J25 Anemia in CHF: True anemia or hemodilution?
J12 HDCN: CKD channel talk links updated
O15 HDCN: CKD - primary care providers vs. nephrologists (audiofiles)
S29 Estimation of CrCl in patients with unstable renal function without urine
S25 Try our upgraded MDRD GFR calculator - See how BUN / Albumin affect the GFR
S03 View ASN-produced video on CKD (for general public)
J04 JASN paper emphasizes risk of ESRD in African Americans
A30 Mercury exposure in dentists linked to memory, kidney problems
A19 CKD guidelines in full posted at www.kdoqi.org
A02 CMS targeting pre-diabetes screening
M28 New NIH-ADA guidelines urge testing of all over 45 for pre-diabetes
M21 K-DOQI guidelines for CKD in full text on AJKD website
F27 Smoking speeds kidney decline in diabetics
F15 JCAHO launches Disease-Specific Certification, starts with diabetes, CHF, asthma
F11 Executive summary of CKD KDOQI guidelines now available (.pdf)
F05 NKF releases K-DOQI guidelines for CKD
J24 NIH CRIC prospective observational study of CKD begins operations
D19 Aspirin and acetaminophen linked to renal insufficiency
O27 K/DOQI expands to form a CV disease workgroup