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HDCN News Archive -- Hypertension, CV Disease
Feb03	Triglyceride levels predict stroke risk in postmenopausal women.
Feb03	Clopidogrel with aspirin does not prevent smaal subcortical strokes; increases bleeding risk
Jan17	Renal denervation surgery now available in Toronto, Canada.
Jan12	What is irisin and how does it regulate brown fat tissue?
Jan12	Routine aspirin may cause harm
Jan10	Dabigatran linked to risk of acute coronary events.
Dec15	Chewsing khat is bad for you if you have heart disease.
Dec13	Statins reduce plaque by affecting the CCR7 chemokine receptor on macrophages.
Dec06	Self-absorbing drug-eluting heart scaffold stent implanted in Montreal.
Nov28	McMaster study published in JAMA suggests a U-shaped relation between sodium intake and CV risk.
Nov28	Similar effects of beer and wine on risk of cardiovascular disease.
Nov21	Higher blood 25-D levels (> 100 ng/dL) linked to new onset atrial fibrillation.
Nov16	Stem cell treatment improves severe CHF in Lancet study.
Nov16	ASN; PRIMO study shows no benefits of paricalcitol on LVH in patients.
Nov16	Higher dose statins reduce coronary artery plaque.
Nov16	American Heart Association Scientific Sessions website.
Nov16	Niacin may not improve hard outcomes.
Nov16	CETP inhibitor more than doubles HDL cholesterol levels.
Nov16	Ain't necessarily so dept: Hypertrophic cardiomyopathy associated with long life.
Nov09	Extra-carotid to internal carotid artery bypass surgery of limited value after ministroke.
Nov01	Am Heart Assoc High BP Research Council Fall 2011 Meeting abstracts
Oct28	Medtronic launches clinical trial of its renal denervation device.
Oct26	Apixaban better than warfarin for atrial fibritllation.
Oct26	Taking at least one BP med at bedtime lowers cardiovascular risk.
Oct20	CDC via MMW publishes usual sodium intakes of US individuals, 2005-2008.
Oct18	St. Jude Medical announces first clinical use of renal denervation technology.
Oct18	BNP biomarker-guided therapy of heart failure markedly lowers complication rate.
Oct14	ASN Renal Week 2011 abstracts now available.
Oct14	MMWR (CDC): Incidence of heart disease in the U.S. declining from 2006 - 2010 (pdf)
Oct14	Bacteria-derived bile acids linked to efficacy of statins.
Oct11	Thiazides may be especially useful to treat hypertension from calcineurin-inhibitor drugs.
Oct11	Link between FGF23 and LVH strengthened by studies in mice, rats, and patients.
Oct04	Salt institute requests that U.S. agencies remove salt restriction from new dietary guidelines.
Sep27	Plaque disruption explains heart attacks in women with normal coronary angiograms.
Sep21	Exposure to vehicle exhaust fumes from traffic can trigger heart attacks with a 6-hour window.
Sep21	cMyBP-C protein may be new diagnostic marker for acute heart attack.
Sep15	Cryoablation treatment of atrial fibrillation shows promise.
Sep15	NEJM: Apixaban better than warfarin to treat atrial fibrillation.
Sep13	Body clock found to regulate platelet function
Sep03	Poor sleep quality increases risk of high blood pressure.
Aug30	Will the chocolate-eating craze impact oxalate load in patients with CKD?
Aug30	European Society of Cardiology 2011 symposium home page
Aug30	Donor heart arrives warm and beating in experimental organ transfer device.
Aug30	Higher salt intake and low activity linked to increased risk of dementia in the elderly.
Aug30	European registry tracks outcomes with ablation therapy for atrial fibrillation.
Aug30	Weight-loss simulatino tool allows prediction of efficacy of dietary interventions for obesity.
Aug30	Adoption study underlines role of genetics in causation of heart disease.
Aug23	New computed tomography heart scan exposes patients to 90% less radiation.
Aug19	High serum phosphorus may accelerate CKD progression, block effects of ramipril.
Aug03	4-D Substudy suggests that low homoarginine levels associate with sudden death.
Jul21	FDA approves ticagrelor (Brilinta) to treat acute coronary syndrome.
Jul21	Stress cardiomyopathy is real and affects a broad range of elderly patients.
Jul19	Intravenous ribose helps recovery from heart attack. A potential dialysate additive to prevent stunning?
Jul19	Carvedilol found to improve intradialytic hypertension in pilot study.
Jul12	Kv7.4 potassium channel in blood vessels linked to control of blood pressure.
Jul12	Therapeutic hypothermia betters outcome post cardiac arrest - why not a dialysis system?
Jul12	FDA approves trial of renal artery SNS ablation by catheter using Ardian/Medtronic system.
Jul12	Higher sodium and lower potassium intake independently link to mortality in NHANES
Jul07	American Heart Association maintains its guidance about 1.5 g/day max sodium intake.
Jul07	Cochrane Library review questions benefits of salt reduction in terms of hard outcomes.
Jul07	Either excessively high or low sodium intake in pregnant rats adversely affects nephron number and kidney function in their offspring.
Jul05	Anti-smoking drug varenicline may have adverse cardiovascular effects.
Jul05	NSAIDs associated with increased risk of atrial fibrillation.
Jul05	Alpha-tocotrienol, a form of vitamin E, may protect brain cells after a stroke.
Jun28	Collagen-binding protein allows dental S. mutans bacteria to attach to heart valves.
Jun28	Visceral fat decreased by increased intake of soluble fiber and exercise.
Jun28	New hybrid minimally invasive surgical procedure to treat atrial fibrillation
Jun21	Shorter pause between stopping CPR and administering electroshock linked to higher survival.
Jun09	FDA-mandated labeling change for simvastatin regarding risk of higher dosages.
Jun09	Pretreatment of mice with thymosin beta 4 induces cardiac repair after induced infarct.
Jun09	SHARP trial (simvastatin plus ezetimibe in CKD) results published in the Lancet.
Jun09	FDA: Myopathy risk of high-dose (80 mg) simvastatin close to 50%; limitations to use recommended.
Jun01	Histone deacetylase inhibitor reverses LVH in a mouse model.
May31	Higher fat, lower carb diets pose little cardiovascular risk over the short term.
May28	MGmin-LDL identifed as a subtype of LDL associated with cardiovascular disease.
May28	Chronic estrogen exposure may increase blood pressure via superoxide; reversed by resveratrol.
May26	Addition of niacin to simvastatin fails to protect the heart and may increase stroke risk
May25	Nineteen percent of young adults found to have high blood pressure.
May22	Epleronone reduces the incidence of atrial fibrillation in class 2 heart failure.
May19	Deuterium-enriched vitamin A slows rate of age-related macular degeneration in a mouse model.
May19	Dairy consumption does not elevate cardiovascular risk in Costa Rican study.
May19	L-arginine-rich foods lower risk of pre-eclampsia.
May17	FDA advisory panel will convene to reconsider approval of fenofibrate
May16	IDOL, inducible LKL receptor degrading molecule, may be target for cholesterol lowering.
May16	KLF14 gene may be a regulator of body fat, obesity, and cholesterol.
May15	Telemedicine monitoring of heart failure patients strikes out.
May12	Losartan might protect against disuse muscle atrophy (in mice).
May03	Link to EPOGH study in JAMA on urinary sodium and CV death risk.
May03	Ain't necessarily so: Observational study suggests lower sodium intake increases risk of death from heart attack and strokes..
Apr29	Work more than 8 hours a day? You may be setting yourself up for a heart attack.
Apr26	25D blood level differences explain 40% of difference in blood pressure between blacks and whites.
Apr25	The cardiologists weigh in on how to treat blood pressure in the elderly.`
Apr25	Oops! High levels of omega-3s, as indicated by DHA, associated with high-grade prostate cancer.
Apr22	Prolongation of the QT interval on sudden standing a marker for sudden death risk.
Apr22	ACE inhibitors may trigger recurrence of breast cancer: an unexpected finding
Apr20	Intensified ultrafiltration in an attempt to control blood pressure linked to more access complications.
Apr20	Calcium supplements linked to increased heart attack risk in older women.
Apr12	On-sitne heart attack response team provides median door to angioplasty balloon time of 47 minutes
Apr12	Vitamin D improves flow-mediated vasodilatation in overweight African American subjects.
Apr12	25D levels below 15 mcg/L linked to increased risk of age-related macular degeneration
Apr07	Ciliary neurotropic factor delivered by encapsulated cells may help age-related macular degeneration
Apr06	Implanted neck baroreceptor buzzer lowers blood pressure in controlled study.
Apr06	Gut bacteria may convert choline to pro-atherogenic compounds. Caution re supplements.
Mar29	Large study using ambulatory BP monitoring shows that many cases of apparent resistant hypertension are really white coat readings.
Mar29	Small, randomized trial of renal denervation shows benefit in treating resistant hypertension.
Mar29	Whole fiber breakfeast cereat consumption associated with lower blood pressure.
Mar24	Ok, you know about FGF23. But FGF19 may be even more important in glucose metabolism.
Mar23	So if we cut out fruits (potassium) and whole grains (phosphate), we also cut out fiber. Is that a good thing?
Mar17	Cardiac injection of autologous stem cells markedly improves heart failure.
Mar12	Disruption of circadian cycle can lead to fatty liver.
Mar12	Coffee drinking linked to reduced stroke risk in women.
Mar12	Wnt1 can stimulate new blood vessel formation and also improve blood flow.
Mar02	Glycogen synthase kinase 3 beta (GSK3B) antibody lowers blood pressure in animals.
Mar02	NSAID use linked to erectile dysfunction
Feb28	Abnormal cubilin gene linked to albuminuria
Feb28	Gut bacteria can affect hepatic lipid metabolism
Feb24	Like pecan pie?
Feb22	Routine measurement of central blood pressure becoming more practical.
Feb18	Where the sodium comes from: sauces, bacon, bread, milk, and cheese
Feb17	New aldosterone-related gene mutation linked to severe hypertension
Feb11	Apixaban may prevent strokes more efficiently than aspirin in atrial fibrillation.
Feb11	New genetic cause of primary hyperaldosteronism identified, and it's not rare.
Feb09	Salt and diet soda ingestion linked to increased risk of cerebrovascular events
Feb07	Pivotal discoveries in age-related macular degeneration.
Jan31	New USDA sodium guidelines recommend sodium intake < 1.5 g/day for individuals with CKD, HTN, or DMj
Jan21	Hickey paralyzes woman (seriously)
Jan15	National Library of Medicine's Daily Med website for quick access to drug package inserts.
Jan14	American Heart Association calling for sodium reduction to 1.5 g/day for everyone.
Jan14	Let me tell you one thing about nurses who eat blueberries...
Jan12	JAMA: Candesartan linked to better survival in heart failure than losartan.
Jan12	Common painkillers linked to increased risk of vascular complications.
Jan12	NEJM: Cholesterol efflux capacity from macrophages, a new measure of HDL action, linked to carotid intima-media thickness.
Jan11	Stem Cell treatment of age-related macular degeneration on the horizon.
Jan10	Statins may be harmful after hemorrhagic stroke.
Jan06	Extended-release clonidine now available for sale in the United States.
Dec28	FDA clears Novartis' triple antihypertensive drug for marketing.
Dec18	FDA approves Medtronic cryoablation device to treat atrial fibrillation.
Dec17	Beetroot juice may increase walking distance in the elderly.
Dec15	Ain't necessarily so: No link between serum 25-D levels and cardiovascular mortality.
Nov30	Source of protection against saturated fat (Angptl4) found, and 3% of people don't have it.
Nov17	Radiofrequency zapping of renal nerves in CKD lowers blood pressure substantially.
Nov17	NEJM: New CETP inhibitor anacetrapib shows promise in affecting LDL and HDL levels
Nov16	Nevada doctor in hot water for prescribing BP pills over the phone without seeing the patient.
Nov16	Xarelto and other warfarin alternatives about to hit the U.S. market.
Nov14	AHA 2010 abstracts: Percutaneous Coronary Intervention in High-Risk Populations: Diabetes and Kidney Disease
Nov14	AHA 2010 abstracts: Diabetes, Metabolic Syndrome and Chronic Kidney Disease
Nov14	AHA 2010 Abstracts: Cardiorenal syndrome: pathophysiology
Nov14	AHA Scientific Sessions ongoing in Chicago, Nov 13-17.
Nov14	Large RCT has good news and bad news for nesiritide (Natrecor).
Nov11	Brass, even in modern plumbing fixtures, continues to cause lead-contamination of drinking water.
Nov08	Cerebral microbleeeds common with aging.
Oct22	Salt sensitivity linked to vasopressin via induction of brain protein synthesis.
Oct18	Susceptibility to hypertension in Blacks may be related to too much aldosterone.
Oct18	Fenretinide reduces the risk of transformation of dry to wet macular degeneration.
Oct15	American Heart Association position paper on smokeless tobacco products.
Oct13	One in five West Virginia 5th graders may have high blood pressure.
Oct13	Want to lower blood pressure? Eat more watermelon for it's L-arginine precursors (but watch the K !)
Oct12	Pharmacy benefits group attempts to predict drug non-compliance at an early stage.
Oct12	International Society for Hypertension in Blacks recommends aggressive treatment.
Oct09	More on FDA-mandated withdrawal of Meridia (sibutramine) from the U.S. market.
Oct05	NIH adds more patients over 75 to SPRINT blood pressure goal trial.
Oct04	New evidence suggests that dietary intake of saturated fats has limited risk of CV disease.
Sep25	Transcatheter aortic valve replacement associated with markedly improved survival.
Sep22	CMS releases new proposed qualiity measures developed by Arbor Research (1.5 mb pdf file)
Sep15	Defective ABCB4 gene impedes cholesterol excretion into the bile.
Sep09	FDA issues new safety alert re gadolinium-containing contrast agents and NSF.
Sep07	Vegetable-based low-carbohydrate diets better than those rich in animal protein
Sep02	NEJM: Increased cardiovascular risk from weight loss drug sibutramine.
Sep02	AASK trial analysis suggests lower BP targets may benefit African Americans with proteinuria.
Aug31	Large study debunks notion that statins may be associated with cancer.
Aug31	Apixaban reduces stroke risk more than aspirin in patients with atrial fibrillation.
Aug26	Analysis of large claims-based dataset suggests heart risks for rosiglitazone and pioglitazone are similar.
Aug26	New NICE hypertension in pregnancy guidelines issued; recommend daily aspirin
Aug26	Back to the future: Renin profiling claimed to be useful in predicting response to RAAS inhibitors or beta-blockers.
Aug26	Naringenin from grapefruits shows promise as a treament for type 2 diabetes
Aug24	Randomized trial shows that drinking water before a meal reduces calorie consumption.
Aug20	Binge drinking markedly increases death risk in subjects with hypertension.
Aug20	Adding fish oil to low fat diet helps metabolic syndrome.
Aug15	ALLHAT long-term follow-up study confirms advantages of diuretics.
Jul30	Calcium supplements increase the risk of heart attack in postmenopausal women.
Jul24	Marcrophage fatty acid synthase a new target to prevent atherosclerosis.
Jul20	FDA approves generic version of transdermal clonidine.
Jul16	APOL1 gene increases risk of kidney disease in African Americans.
Jul15	ACCORD (NEJM): HbA1c target < 6% and combo statin/fenofibrate Rx better for retinopathy.
Jul12	Abstracts from 2010 World Congress of Cardiology - Posters (274 page .pdf)
Jul12	World Congress of Cardiology 2010 oral presentation abstracts (100 page .pdf)
Jul08	Cholesterol can exit the blood via the liver into the intestine while bypassing bile.
Jul06	Got a thick neck? Might not be so good if you're a child.
Jul06	Cocoa flavanols increase angiogenic cell number.
Jul06	INVEST study published in JAMA: No benefit of targeting BP < 130/80 in diabetics vs. 130-140
Jul06	How water drinking increases blood pressure and sympathetic activity.
Jul02	Olive oil consumption downregulates gene activity associated with atherosclerosis.
Jul02	Sugary drink consumption raises risk of hypertension.
Jun30	NEJM: Is computed tomography safe?
Jun29	Can't decide if rosiglitazone is safe for the heart? Ask Consumer Reports.
Jun29	Video presentation summary of ACCORD trial results.
Jun29	KDOQI CKD guideline of BP < 130/80 is being questioned.
Jun29	Beetroot juice in the news as a means of lowering blood pressure and CV risk.
Jun29	New study shows no increased cardiovascular risk due to rosiglitazone.
Jun24	Selective estrogen compound activates cell-surface receptors only, may confer vascular protection.
Jun22	European Soc Hypertension 2010 meeting abstracts - June 21st.
Jun22	European Soc Hypertension 2010 meeting abstracts - June 19th.
Jun22	European Soc Hypertension 2010 meeting abstracts - June 19th.
Jun22	ENDO 2010 "abstracts 2 view"
Jun22	Daily new reports of ENDO 2010 meeting
Jun22	Genetic septet in control of platelet stickiness.
Jun18	Blood pressure of 110 and above in teenage boys presages HTN.
Jun13	Lancet study suggests that ARBs may be associated with a higher rate of lung cancer.
Jun11	Short stature increases risk for heart disease: an important confounder for BMI
Jun10	Bipolar disorders linked to hypertension
Jun10	Allopurinol markedly slows progression of CKD in small randomized trial.
Jun10	Why did heart attacks go down by 24% in Northern California's Kaiser patients?
Jun10	Continuous aspiration thrombectomy helps return brain function post major strokes.
Jun10	Ghrelin acting on MC4 receptors in the brain shown to affect serum cholesterol levels.
May30	The politics of salt reduction: the food industry fights back.
May29	Abstracts of the High Blood Pressure Research Council of Australia 31st Scientific Meeting.
May26	Drinking fewer sugar-sweetened beverages may lower blood pressure.
May26	B cell genes characterize transplant patients who do well after stopping immunosuppressives.
May26	High levels of HDL cholesterol do not always protect.
May21	Use of Viagra associated with long-term hearing loss.
May18	Pregnenolone sulfate may reduce inflammatatory mediator production by blood vessels.
May18	Higher blood pressure found in people living in urban areas
May12	Working overtime increases heart risk
May06	Having a TIA? Eat some dark chocolate.
May06	New atherosclerosis gene gives promising results.
May05	Mitochondrial DNA strongly linked to stroke risk
May04	American Society of Hypertension program book (see RSS feed for audiofile link)
Apr30	SHR (spontaneously hypertensive rat) genome sequenced - 788 mutations found!
Apr30	New gene link to scleroderma found
Apr28	Anabolic steroid use in healthies impairs left ventricular relaxation by 50% and also ejection fraction.
Apr28	RCT shows that high-dose B vitamins associated with increased risk of progression and CV events in diabetics.
Apr20	About 6 kg of weight loss in obese subjects markedly reduces pro-inflammatory immune dysfunction.
Apr20	Institute of Medicine sodium report - full text
Apr20	FDA Statement on Institute of Medicine sodium report
Apr20	Institute of Medicine, Harvard researchers call for rules for sodium reduction in food
Apr20	Diets high in added sugar raise heart disease risk.
Apr19	Bad news and more bad news: Gene that makes you fat melts your brain.
Apr19	Gamma prime fibrinogen levels in the top quarter equals a 7-fold increase in MI risk
Apr14	Bariatric surgery lowers pregnancy complication risk in obese women
Apr13	High glycemic index carbs increase heart risk in women.
Apr11	Generic losartan and losartan + HCTZ now available
Mar30	Eating 1 small square of chocolate per day lowers CV risk by 39%
Mar23	High-fructose corn syrup associated with liver scarring in patients with NAFLD.
Mar22	Inventor of beta-blocking drugs, Scottish scientist Sir James Black, dies.
Mar22	NDT early: Hemodialysis causes microemboli to enter the circulation.
Mar22	Fibrillin-1 and TGF beta linked to scleroderma
Mar22	High fructose corn syrup = table sugar in terms of fructose content, but not in terms of obesity.
Mar19	JACC paper: Rosuvastatin in CKD subgroup of the JUPITER trial
Mar19	High-dose rosuvastatin reduces mortality in CKD patients by 44%.
Mar15	Valsartan and nateglitidine of no use in reducing CV death in prediabetics.
Mar15	Level of myeloperoxidase strongly associated with CAD mortality.
Mar15	ACCORD trial combination fibrate plus statin results (NEJM, pdf)
Mar15	ACCORD trial lower BP target results (NEJM, .pdf)
Mar15	ACCORD trial results released at ACC: BP lower than 120 or addition of fibrates have no benefit in diabetics.
Mar12	Plavix gets new FDA warning regarding reduced efficacy in 3% slow activators.
Mar12	Spikes in blood pressure predict stroke risk better than high average readings.
Mar11	NEJM: Thyroid hormone analogue lowers LDL cholesterol in statin-treated patients.
Mar04	NEJM: Glycated hemoglobin linked to CV death risk in nondiabetic adults.
Mar02	3 different diets equivalent in terms of improving carotid artery atherosclerosis.
Mar01	Leukocyte biology suggests that simvastatin may increase infection risk.
Feb23	AHA/ACC issue Science Advisory re heart risk and thiazolidinedione drugs.
Feb23	New cardiac CT scanners with 320 detector rows expose patients to 90% less radiation.
Feb22	Mutations in gene encoding K channel KCNN3 associated with atrial fibrillation.
Feb12	Tetrahydrobiopterin (BH4) a drug already used in humans, prevents diastolic heart failure in mice.
Feb10	Statins associated with a 40% reduction in risk of cataracts
Feb09	Even mild hypokalemia in heart failure patients with early-stage CKD associated with increased mortality.
Feb08	What is "third-hand smoke" and why is it potentially dangerous?
Feb04	New metaanalysis debunks link between saturated fat intake and heart disease.
Jan27	ASH 25th Annual Scientific Meeting to be held May 1-4, 2010 in New York City.
Jan27	Think you know how platelets are made? Guess again.
Jan27	New software allows 3D imaging during coronary angiography.
Jan26	AJKD: Comments on AURORA study results on use of statins in CKD patients.
Jan25	MMWR: Prevalence of abnormal lipid levels among youths
Jan21	NEJM study quantitates benefits of salt reduction on CV outcomes.
Jan14	Alzheimer's disease might be detectable by a retinal exam.
Jan13	BPA (bisphenol A) linked to cardiovascular risk.
Jan12	Intranasal and intracranial TGF-alpha restores motor function after stroke in rats.
Jan11	CV and kidney progression risk tied to proteinuria may be affected by race.
Jan07	UCLA study shows metformin to be safe in patients with diabetes and advanced heart failure.
Dec29	Inner ear organs can alter brain blood flow, affect postural hypotension, dizziness.
Dec29	Renal sympathetic nerve ablation being tested in the UK to treat hypertension
Dec23	American Heart Association's selection of top 10 research advances
Dec23	Aggressive BP treatment in patients over 80 may result in increased mortality.
Dec21	24-h BP monitoring disturbs sleep in some, artifactually affecting the amount of nocturnal BP dipping.
Dec21	Genetic studies clarify differing European and West African components of inheritance in African Americans
Dec07	NEJM: Dabigatran as good as warfarin for venous thromboembolism prevention.
Dec04	Blood clot risk increased up to 70 times as long as 6 weeks after surgery.
Dec02	Heart failure linked to gene variant affecting vitamin D activation.
Dec01	TLR2 (toll-like receptors) linked to inflammatory damage in atherosclerotic plaque.
Nov27	Stress-related blood pressure linked to phosducin.
Nov26	Instead of looking to get omega-3s from fish, look to the algae.
Nov25	Feeding time a major factor on gene induction circadian variability
Nov25	High salt intake linked to risk of stroke and cardiovascular disease.
Nov25	Nexilin mutations identified as a cause of dilated cardiomyopathy.
Nov19	Workers exposed to secondhand smoke in outdoor environments have elevated blood levels of cotinine.
Nov19	Cigarette smoke found to be contaminated with many pathogenic bacteria.
Nov18	Niacin plus statin no better than niacin alone in elderly patients with CAD.
Nov18	NEJM: IV iron improves functional capacity and QOL in heart failure patients with iron deficiency
Nov17	Scientific sessions of the American Heart Association portal
Nov17	FDA: Omeprazole and clopidogrel drug:drug interaction reducing efficacy of clopidogrel
Nov17	NEJM: Continuous flow LV assist devices markedly improve survival in severe heart failure.
Nov15	NEJM: Editorial regarding the HALTS trial (ezetimibe vs. niacin)
Nov15	NEJM: Extended-release niacin better than ezetimibe (Vytorin) for atherosclerosis reduction
Nov14	ASTRAL study published in NEJM: No benefit of revascularization in renovascular hypertension.
Nov14	Children with CKD often have undetected hypertension that is associated with LVH.
Nov14	Excessive ingestion of selenium supplements can increase cholesterol by 10%
Nov14	Getting fat recently? Maybe too many Firmicutes bacteria in your gut.
Nov10	Obesity and hypertension are independent risk factor for left atrial enlargement with aging.
Nov06	CJASN: Higher phosphorus levels in preESRD patients linked with coronary artery calcification.
Nov04	Off-pump bypass surgery comes up short in RCT against older method
Nov03	Role of aspirin in primary prevention of cardiovascular disease being questioned.
Nov03	Statins may protect against deep venous thrombosis
Oct29	NIH launches SPRINT RCT to study systolic BP target effect on progression into CKD.
Oct26	Blue-light filtering increases macular pigment, may protect against dry macular degeneration.
Oct13	Melanocytes in the heart? Protecting against atrial fibrillation?
Oct06	Cochrane review finds that B-vitamins of no benefit in preventing CV complications.
Oct06	Minocycline protects against ischemic stroke in animal models.
Oct01	JASN: Pioglitazone prevents age-related decline in renal morphology and function.
Sep24	Vitamin D deficiency in premenopausal women associated with hypertension later in life.
Sep24	200g/day fructose supplement increases systolic BP by 6 mm Hg, prevented by allopurinol.
Sep24	AJKD issues containing KDOQI guidelines now freely available as .pdf files
Sep17	Vitamin K deficiency may be widespread, according to a new theory.
Sep14	Implantable defibrillators may not benefit women.
Sep01	European Soc Cardiol 2009 meeting website
Sep01	Addition of valsartan lowers CV mortality in Japanese patients in the Kyoto heart study.
Sep01	Early stage CHF patients benefit from cardiac resynchronization therapy.
Sep01	How much DHA is enough for an anti-atherosclerotic effect? 200 mg
Sep01	Prophylactic use of aspirin in asymptomatic atherosclerosis of no benefit in RCT.
Sep01	CO linked to increased CV risk; might this explain the higher CKD risk as well in urban areas?
Sep01	Hormonal therapy for prostate cancer associated with increased cardiovascular risk.
Aug30	NEJM: Ticagrelor better than clopidogrel as an anti-platelet agent post acute coronary syndrome.
Aug30	NEJM: Free full text paper on dabigatran vs. warfarin for stroke prevention in atrial fib.
Aug30	Pradaxa (dabigatran) outperforms warfarin by a mile for stroke prevention with a. fib.
Aug28	About 1/3 of people don't activate clopidogrel very well due to gene variants.
Aug28	Should pregnant women avoid mushrooms? Ergothioneine levels high in pre-eclampsia
Aug28	New gene controlling formation of adipocytes identified.
Aug28	Warfarin use associated with increased stroke risk in hemodialysis patients with a. fib.
Aug24	Mice eating a low-carb diet show increased atherosclerosis and decreases in vascular progenitor cells.
Aug24	Is reduction in liver fat the key to the benefits of an alternate-day diet?
Aug24	FDA announces ongoing monitoring of liver injury associated with Orlistat.
Aug21	Excess cholesterol can affect heart rhythm via potassium channels
Aug21	When vitamin D levels low, macrophages get overloaded with cholesterol.
Aug20	Oxycholesterol an important new heart disease risk; high in fried fatty foods.
Aug19	Klotho gene reduces blood pressure and extends lifespan.
Aug18	Whole grain cereals have polyphenol content similar to fruits and vegetables.
Aug06	Blood transfusions in cardiac patients associated with markedly increased mortality.
Aug06	Hypertension associated with VEGF-inhibitors linked to nitric oxide.
Aug03	Millions of U.S. children low in vitamin D
Aug03	TV viewing time associated with higher blood pressure in children.
Aug03	Evidence mounts for cardioprotective effects of fish oil.
Jul31	Lecithin found to have beneficial effects on fat metabolism via PPAR-alpha
Jul31	Monocytes from spleen involved in recovery from myocardial infarction
Jul28	NIH halts trial of sildenafit in patients with sickle-cell disease and pulmonary hypertension.
Jul28	Like chocolate: Low-cal variety on the way (but watch out for the oxalate).
Jul26	Diets high in linoleic acid associated with increased risk for inflammatory bowel disease.
Jul21	In diabetics with heart failure, HbA1c levels of 7.1 to 7.8 at lowest risk of death; tighter control bad.
Jul13	Citrus-derived flavonoid prevents obesity and metabolic syndrome in mice.
Jul08	Is PEDF "the" link between obesity and type 2 diabetes?
Jul08	Study examines effects of stress on weight gain in US population
Jul08	Cochrane review suggests no benefit of lowering blood pressure below 140/90
Jul08	Anti-ageing effects of rapamycin in mice in the news.
Jul05	Aldosterone regulates ENac levels via Per1 - a protein mediating circadian rhythms.
Jul02	U.S. obesity problem intensifies.
Jul02	Enalapril or losartan markedly slow progression of eye damage in type 1 diabetics.
Jun30	Genetic study suggests that relationship between C reactive protein and CV disease is not causal.
Jun26	FDA to regulate tobacco.
Jun24	Analysis of large number of bariatric surgery patients shows the procedure to be relatively safe.
Jun19	Clopidogrel may increase risk of death in patients with diabetic nephropathy.
Jun17	Annals: Stents of no benefit in treating renal artery stenosis
Jun13	Higher vitamin D levels associated with successful weight loss in obese subjects on a diet.
Jun05	Aldosterone levels found to be increased in chubby teenage boys.
Jun01	Modified lycopene extract (ateronon) reduces harmful oxidation of fats.
May30	Results from 8 late-breaking clinical trials at Heart Failure 2009
May29	Risks of aspirin outweight benefits for primary prevention of stroke, MI in those with normal kidney function.
May26	Simplified chart may aid in diagnosing hypertension in children.
May25	Search all abstracts from the World Congress of Nephrology 2009
May25	Gene variant found that increases risk of both severe periodontitis and myocardial infarction.
May22	Fenofibrate reduces amputation risk in diabetics.
May18	Heart disease patients who are overweight do better and live longer.
May15	Use of CT angiography in the emergency room to help diagnose chest pain found to be cost-effective.
May15	JASN early release: Low 25-D levels associated with coronary artery calcification progression
May15	High triglyceride levels associated with diabetic neuropathy
May15	Interventional study in mice links cytomegalovirus infection to high blood pressure.
May14	Monotherapy with DARA, an endothelin and angiotensin I receptor antagonist, lowers BP a lot.
May14	ALLHAT follow-up study confirms benefits of chlorthalidone.
May11	UMOD gene, associated with Tamm-Horsfall protein production, linked to kidney disease.
May11	Cyclophilin may play a key role in arterial damage associated with atherosclerosis.
May11	Vitamins C and E block improvement of insulin sensitivity with exercise.
May08	Low BP associated with strokes and MI in patients with coronary artery disease.
May08	Combining dieting with exercise while standing/sitting/kneeling on a vibration plate machine lowers abdominal fat.
May04	8th Annual Prevention in Renal Disease Conference, September 25-26, 2009 in Toronto.
Apr30	Urine screening test seems to predict presence of atherosclerotic disease.
Apr26	Statins may reduce prostate inflammation and reduce risk of prostate cancer
Apr26	Sodium in prepared foods frustrates attempts to implement low sodium diet in CHF patients.
Apr26	Prostaglandin 2-alpha may be new target for control of blood pressure and atherosclerosis.
Apr23	Low-sodium vegetable juice may help reduce body fat in patients with metabolic syndrome.
Apr22	Alzheimer beta-amyloid can be degraded, and some drugs can increase breakdown rate 7-fold.
Apr18	New stem cell treatment for age-related macular degeneration in development.
Apr17	New discoveries on how collagen activates platelets may lead to new treatments to prevent clotting.
Apr16	Heart risk in diabetics may be exaggerated.
Apr16	Endothelin A receptor antagonist darusentan shows promising results in resistant hypertension.
Apr14	Aspirin and similar drugs associated with brain microbleeds in the elderly.
Apr12	CXCL5, secreted by white adipose tissue, may be the link between obesity and inflammation and insulin resistance.
Apr11	Three papers on brown adipose tissue in this week's NEJM.
Apr11	One thousand 2007-2009 audiofiles and slide/audio talks added to HDCN's 20 topic-related channels.
A07	Chemokine CXCL5, produced by fat cells, linked to inflammation and insulin resistance.
A06	Chlorthalidone increases SNS activity, spironolactone does not
A01	Yeast-powered fuel cells (for implantable devices) derive energy from glucose in human blood.
M30	GNSOR-deficient mice markedly resistant to heart attacks.
M30	Lipoic acid supplements markedly lower triglycerides in an animal model.
M30	AURORA study confirms the 4D study: Statins of no benefit in dialysis patients.
M30	Radiofrequency ablation of renal sympathetic nerve activity results in sustained improvement in refractory hypertension.
M30	NEJM: Ventriculoplasty of no benefit when added to CABG in patients with CAD and heart failure.
M29	Link to slide/audio and audio symposia on HDCN
M29	American College of Cardiology 2009 - Day 3 newsletter
M29	American College of Cardiology 2009 - Day 2 newsletter
M29	American College of Cardiology 2009 - Day1 newsletter
M29	Crestor (rosuvastatin) lowers risk of venous thromboembolism by 34%.
M28	Corking shut the atrial appendage markedly reduces risk of stroke in patients with atrial fibrillation.
M26	AHA supports a lower sodium intake limit (1.5 g Na/day) for most Americans.
M26	Testing for endothelial function using a finger device that evaluates reactive hyperemia linked to CV outcomes.
M26	Preliminary data show potential benefits of catheter-based thrombolysis for stroke.
M26	Cholesterol crystals linked to arterial plaque disruption and heart attack.
M22	Ten genes associated with prolonged QT syndrome and risk of sudden cardiac death.
M22	Correct warfarin dose determined by 3 genes only.
M20	FDA panel gives nod to alternative to warfarin
M18	Another statin (Crestor, rosuvastatin) fails to show a benefit (rumor has it) in dialysis patients.
M17	Endothelial lipase linked to levels of good cholesterol
M12	HDL levels and glucose sensitivity linked to neck circumference.
M12	New anti-clotting compound derived from magnolia trees shows encouraging results in phase II safety study.
M09	Eating fish associated with increased intelligence in Swedish teens.
M04	Reduction of stroke risk associated with green/black tea drinking appears consistent and linear.
F26	Cornell researchers develop and market a point-of-care urinary sodium test strips to monitor salt intake.
F25	NEJM: Randomized trial of 4 different diets (low fat, low CHO, etc.) fails to find a single winner.
F23	Genes controlling atrial natriuretic peptide expression linked to hypertension.
F18	NEJM: Genetic testing helps predict warfarin dose.
F17	Ain't necessarily so series: oxidative stress may prolong, instead of shorten, life (worm study)
F11	Very high doses of candesartan effective in further reducing proteinuria.
F10	Vigorous exercise (running) may reduce the risk of age-related macular degeneration.
F10	American Heart Association focuses on the high risk of stroke in women
F09	LSR, lipolysis-stimulated lipoprotein receptor, found to be deranged in type 2 diabetes with obesity.
F03	Short-term growth hormone treatment attenuates muscle loss after bariatric surgery.
F03	FOXO3A gene variants associated with living beyond 100 in multiple parts of the world.
J30	Epoxide hydrolase inhibitor reduces heart failure in animal model
J30	Sulfenic acid may be reason for potent anti-oxidant effect of garlic.
J30	FDA mandates detailed hyperkalemia warning for Aldactone (spironolactone)
J28	The new study that caused the fuss about clopidogrel and proton-pump inhibitors.
J28	FDA cautions on combined use of clopidogrel and proton-pump inhibitors until more info is obtained.
J26	Animal study suggests benefit of statins in preventing stroke in patients with cerebral cavernous angioma or malformation.
J20	Randomized (DRIP) trial reports benefits of dry weight reduction in dialysis pts. on 24-h blood pressures.
J19	Three new genes linked to childhood obesity identified.
J19	Trial of stem cell treatment to treat stroke patients approved for recruitment.
J19	Indian subcontinent heart disease gene identified.
J17	Heart and Stroke Foundation of Ontario issues "alert" against combined use of ACEIs and ARBs.
J15	Source of endogenous salicylic acid identified as benzoic acid found in fruits and vegetables.
J12	High sodium to potassium ratio in the urine increases cardiovascular event rate.
J09	New anti-anginal drug acts by working on sodium channels.
J01	New Year's Resolution? Quit smoking. American Lung Association support info.
J01	MMWR: Lower acute MI rates after city implements smoke-free ordinance
D29	Study of Amish identifies a new gene linked to sodium control and hypertension
D18	JASN early: First morning urine better than spot urine to detect microalbuminuria
D15	FDA approves premounted renal stent system manufactured by Boston Scientific
D14	Study in the Amish links APOC3 gene mutation, triglycerides, and resistance to heart disease.
D13	New study shows links between 30 genes and cholesterol and triglyceride levels.
D13	Should nephrologists give beta-blockers to their patients with CKD?
D11	CJASN: Rosiglitazone may benefit patient with FSGS
D09	Statins adversely affect placental development in an in vitro model.
D04	NEJM study shows that irbesartan of no benefit to patients with diastolic heart failure.
D04	Liver fat, rather than abdominal fat or shape, may be main cardiovascular risk.
D03	NEJM: ACEI plus amlodipine better than ACEI plus a thiazide in terms of cardiovascular events.
D02	Depression increases risk of subsequent visceral fat gain in longitudinal study.
D02	Consumer Reports investigates sodium content of foods: salt is present where one may not expect
D02	Cardiologists debate NEJM study comparing coronary CT scans with percutaneous angiography.
D01	Canadians publish best practice recommendations for stroke care.
N27	New studies confirm importance of sirtuin pathway in mammalian ageing; attention focuses on resveratrol.
N26	Binge drinking may damage the heart via acetaldehyde activation of macrophages.
N21	Do your CKD patients still smoke? Who is still smoking in the US by state.
N18	New microRNA compound protects mice against heart failure.
N14	Renal Week: Relative vitamin K2 deficiency linked to vascular calcification in ESRD
N13	Catheter thermoablation of atrial fibrillation far superior to drug treatment.
N13	FDA: Review of atrial fib - bisphosphonate data suggests a weak or no relationship.
N11	Sleep apnea associated with increased risk of sudden death.
N11	AHA Scientific Sessions 2008 in New Orleans, LA: Daily News, Nov 8 -12.
N09	Rosuvastatin given to patients with normal cholesterol levels but high CRPs markedly lowers CV risk.
N04	Intraocular anti-VEGF drugs to treat retinal proliferative disoders may have a dark side.
N04	New SIRT1 activating drug may protect against diet-induced obesity.
O30	MYH9 gene variations linked to CKD in African Americans - researchers to present new data at Renal Week 2008.
O29	Grapes protect the hearts and blood pressure of rats fed a salty diet.
O28	VEGF-based screening test for pre-eclampsia foreseen based on new research.
O28	French company develops a next generation totally implantable artificial heart.
O28	Plavix (clopidogrel) may be inactivated by some calcium channel blockers.
O27	Runners burn more calories at rest than sedentary persons, and it's due to changes in the mitochondria.
O27	Risks of irregular heartbeat and atrial fibrillation increased with fosamax and other bisphosphonates.
O27	Pregnant women consuming flaxseed oil have a high (4x) risk of premature birth.
O27	Pentoxifylline lowers proteinuria alone or in addition to an ACE inhibitor.
O23	Hydrogen sulfide may be a key regulator of blood pressure.
O23	European watchdog agency suggests not using diet drug rimonabant due to depression side effects.
O23	New diet drug tesofensine appears to be remarkably effective.
O22	Journal of Renal Nutrition publishes composition of common salt substitutes.
O16	Fructose feeding induces high triglycerides and leptin resistance in rats.
O15	Resveratrol prevents liver fat accumulation in a mouse model of alcoholic liver disease.
O14	Resveratrol found in dark chocolate and cocoa.
O14	B vitamins of no help in slowing progression of Alzheimer's disease.
O13	Book Review: Clinical Guide to Use of Antithrombotic Agents in CAD
O13	Are you nuts about nuts? Nuts! One study fails to shell out any benefit.
O13	A series of abstracts presented at CRF meeting suggesting that triple anti-platelet therapy (adding cilostazol) improved outcomes.
O09	Retinylamine markedly slows age-related macular degeneration in an animal model.
O09	New physical activity guidelies: 30 minutes of moderate exercise 5 times per week;
O08	A single dose of EPO injected after a heart attack can limit apoptosis and thereby reduce heart cell damage.
O07	Farnesyl transferase inbitior (tipifarnib) reverses cardiovascular effects of progeria.
O07	Study illustrates importance of inflammatory macrophages in obesity; insulin resistance reversed by killing these cells.
O07	Even occasional smoking can impair arterial function for a prolonged period.
O07	Complement pathway and the innate immune system implicated in age-related macular degeneration.
O06	One-dollar-a-month polypill containing ASA, thiazide, ACEI, and statin to undergo clinical testing.
S30	Lancet: New genes found that link to gout.
S26	Aptly named horny goat weed found to be a source of specific phosphodiesterase inhibitors.
S25	In humans, as opposed to lab animals, caloric restriction does not lower IGF-1, but protein restriction does.
S22	Darapladib slows atherosclerosis in a pig model.
S22	Secondhand smoke exposure increases risk of peripheral artery disease in women.
S19	High-salt diet contributes very substantially to resistant hypertension.
S18	Are statins ineffective for protection against cardiovascular risks in women?
S18	New mechanism for cardiac arrhythmia discovered.
S18	Listening to Mozart lowers high blood pressure (really)
S16	NHANES data analysis links elevated urine bisphenol levels to diabetes, cardiovascular disease.
S16	Conbining thiazides with potassium-sparing diuretics markedly lowers cardiovascular mortality.
S15	Carvedilol and alprenolol, but not other beta-blockers, stimulate cellular protective pathway in the heart.
S12	Cardioprotective effects of alcohol ingestion may be due to aldehyde dehydrogenase.
S10	NEJM early release: Benefits of tight glucose control persist in type 2 DM at 10 years
S10	NEJM early release: Tight BP control has to be continued in type 2 diabetics; otherwise benefits are not maintained.
S05	Photographing what they eat helps dieters stick to weight-loss plans and identifies bingeing.
S02	Want to live longer? Take the stairs instead of the elevator.
A29	Singh and Furberg editorialize against use of thiazolidinediones due to CV risk and lack of CV benefit.
A29	100g/day of dark chocolate lowers blood pressure by 3 mm Hg.
A27	Debate flares: Can obese patients be healthy?
A26	Allopurinol lowers blood pressure in hypertensive adolescents
A26	Newer gated CT scans diagnose coronary artery disease and obviate need for angiography.
A22	Some evidence that Vytorin is, or maybe is not, associated with an increased cancer risk; FDA gets involved.
A21	AMAG receives fast track designation from FDA for ferumoxytol as an MRI contrast agent.
A19	Lowering homocysteine with folic acid and B vitamins fails to reduce CV events in heart disease patients.
A19	Obesity epidemic due to increased food intake, and not decreased activity level.
A15	When is a potential heart donor really dead? NEJM report raises some ethical questions.
A15	Lancet: ONTARGET study shows mixed results for combined ARB/ACEI therapy; greater reduction of proteinuria but a higher renal event rate.
A15	Bariatric surgery - induced weight loss helps, but does not cure, sleep apnea.
A13	Enhancing lysosomal receptors for chaperone molecules prevents aging of mouse livers.
A12	MicroRNA specific to endothelial cells associated with blood vessel branching, survival after cardiac infarction.
A08	FDA issues warning about risk of rhabdomyolysis when simvastatin is used with amiodarone.
A08	AHA issues recommendations for ambulatory BP monitoring is certain children and adolescents.
A05	IV calcium channel blocker wins FDA approval to treat acute hypertension.
A05	Baroreflex device to treat hypertension. A pipe dream? 200 million dollars raised so far says maybe not.
J31	Two new drugs have profound effects on exercise conditioning in mice.
J30	Does adiponectin have a dark side? Study associates it with increased cardiovascular risk.
J29	New study highlights risk of losing bone density while following a low-calorie diet for weight loss.
J29	Rember, a drug that is really a blue dye that prevents tau tangles, appears to slow Alzheimer's disease.
J29	Testosterone changes associated with perimenopausal increase in metabolic syndrome risk.
J29	Observational study suggests that statins may lower risk of senile dementia very substantially.
J24	Complement activation is increases in patients with age-related macular degeneration.
J24	In acute study, fructose increases lipogenesis relative to glucose.
J23	NEJM: Genetic mutation associated with most patients who develop myopathy on high-dose statins.
J22	Ezetimibe plus simvastatin drug trial shows no effect on aortic valve stenosis progression.
J19	Human blood vessels grown in mice
J17	Genetic variant identified that increases risk of elevated triglycerides fourfold in Asian Americans.
J17	U.S. population keeps getting fatter; esp. Alabama, Mississippi, and Tennessee.
J17	AHA to launch new journal focusing on cardiovascular outcomes trials and methodology.
J16	Doctors hopeful that improved blood thinners are on the horizon: Three new candidates.
J16	Annals: Low molecular weight heparin for 7 days better than stockings after arthroscopic knee surgery.
J12	Pioneering heart surgeon Michael DeBakey dies at age 99.
J10	Histone deacetylase (HDAC) inhibitors protect ischemic tissue from injury.
J08	Farm-raised tilapia fish has relatively low levels of omega-3 fatty acids.
J08	Fish oil plus red yeast lower cholesterol to the same extent as statin therapy.
J08	Overweight patients trying to lose weight lose twice as much if they keep a food diary.
J03	Statins spur glial progenitor cells to develop into oligodendrocytes.
J01	Caffeine intake increases rate at which muscle replenishes glycogen stores after exercise.
J01	Doxycycline-inhibitable protease activity increased in SHR rats; this also may explain various aspects of metabolic syndrome.
J30	AHA publishes cookbook focusing on healthy soul food recipes
J30	Sudden hearing loss associated with increased risk of future stroke.
J30	AHA launches hearthub.org, a website for patients.
J30	Prevalence of silent cerebral infarction in healthy (mean age 62) people at 11% in MRI study.
J26	Fructose, but not glucose, increases visceral adipose tissue and triglycerides, and lower insulin sensitivity.
J25	African Americans excrete less potassium in the urine, and it's not all due to dietary intake.
J25	Obesity drug rimonabant approved for NHS use in England and Wales.
J23	New source of cardiac stem cells found in the epicardium
J17	Big breakfast diet more effective than low-carb diet in maintaining weight loss.
J12	XBP1, stimulated by a high-carb diet, may be a new target for treatment of dyslipidemias.
J12	A subgroup of retinal cells linked to circadian cycle resetting and insomnia.
J12	FDA approves generic form of ramipril made by Lupin pharmaceuticals.
J11	Vitamin D protects heart-failure-prone rats against heart failure when fed a high-salt diet.
J10	One more argument against smoking: Increased risk of age-related hearing loss.
J10	Eating diet rich in oily fish associated with markedly reduced risk of age-related macular degeneration.
J09	115 year old woman found to have essentially normal brain on autopsy, with no evidence of Alzheimer's disease.
J06	Mechanism of action of niacin to increase HDL levels discovered.
J05	Study in mice suggests resveratrol has marked cardioprotective effects.
J05	NEJM: Aliskiren plus losartan lowers proteinuria in diabetics.
J03	Artificial blood vessel creation from smooth muscle cells makes major advances.
M28	Hope for stroke victims. Monkeys control prosthetic arm using brain waves to feed themselves.
M27	New scoring method for coronary artery calcification that takes into account extent of calcium coverage.
M27	Should HbA1c be used instead of plasma glucose to screen for diabetes?
M22	It's official: Home BP monitoring is now the standard of care.
M21	Genetic researchers identify numerous genes involved in synthesis and storage of fat in cells.
M21	After heart attack, bivalirudin better than heparin plus glycoprotein IIb/IIIa inhibitors.
M21	Modest red wine (but not beer) ingestion actually may lower risk of NAFLD - non-alcoholic fatty liver disease.
M20	Small adrenal masses found incidentally on computed tomography almost exclusively benign.
M19	Vaccine targeting amyloid beta protein prevents Alzheimer's disease in mice.
M19	American Society of Hypertension Annual Meeting (May 14-17) - abstracts at this link
M16	Small molecule found that can disassemble amyloid proteins associated with Alzheimer's disease.
M16	New NHANES analysis finds CV mortality increased in patients following a lower salt intake.
M15	Lower-dose tissue plasminogen activator treatment improves survival in patients with hemorrhagic stroke.
M15	Biopterin derivative may be effective treatment for severe heart failure.
M13	Preop beta blockers reduce heart attack risk but markedly increase total mortality.
M13	Prism eyeglasses expand view for patients with stroke-induced hemianopia.
M12	CPR rescuers do not need to stop compression while administering defibrillator shocks.
M12	Preeclampsia-like condition develops in mice with knockout of catechol-O-methyltransferase (COMT) gene
M09	Darapladib lowers the activity of inflammatory enzyme associated with vascular plaque.
M07	S100A1 protein found in heart, blood vessels; linked to heart damage and to hypertension.
M07	Women at high risk for CV events are not benefitted by homocysteine-lowering regimen of B vitamins (JAMA).
M05	ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format.
M04	Nature genetics: More obesity genes found
M02	New ACE 2 activator compounds lower blood pressure in rats and also reduce cardiac and renal fibrosis.
M01	Obesity linked to heart failure and inflammatory mediator elevation in observational study.
A30	Scientists synthesize molecule capable of releasing hydrogen sulfide over extended periods - possible role in donor organ preservation?
A29	High blood theobromine levels (presumably from eating chocolate) may protect against pre-eclampsia.
A28	Hypertension seen in the emergency department frequently misattributed to trauma, stress, and not followed up.
A25	First ever activator of ENAC sodium channel developed.
A23	High adiponectin levels linked to kidney dysfunction and albuminuria.
A22	FDA approves compact heart assist device from Thoratec.
A21	International study of chemicals in urine links blood pressure to diet and gut bacteria.
A21	Chocolate lowers LDL cholesterol by 5% in RCT.
A17	Low serum 25D levels associated with incrased peripheral arterial disease risk.
A15	Archives Int Med: Loop diuretics associated with lower bone density in men.
A15	Nurses' Health Study shows that women who follow DASH - type diet have lower risk of heart attack.
A09	NEJM: ACEI = ARB, and ACEI + ARB no better than either ACEI or ARB, in high risk patients with diabetes or vascular disease.
A09	Two enzymes associated with acetylation linked to heart muscle contraction.
A09	New Lifton study shows that some Bartter and Gitelman mutation heterozygotes are not rare, and are protected against hypertension.
A09	JAMA RCT shows American Indian tye 2 diabetics with LDL lowered to 70 have lower carotid IMT and LV mass than those with LDL lowered to 100.
A08	Slight modification to atrial fibrillation surgery improves the results.
A08	American Heart Association issues new guidelines for treatment of resistant hypertension.
A03	Daily dose of caffeine protects rabbit brains from high serum cholesterol.
A03	New Merck heart failure drug rolofylline gives encouraging results in Phase III trial.
A02	Treating hypertension in patients more than 80 years of age reduces death rate by 20%.
A02	Adenosine receptor antagonist shows promise in heart failure.
M30	NEJM: Ezetemibe lowers LDL cholesterol when added to simvastatin, but no effects on carotid artery thickness.
M27	Pretreating animals with high-dose folate lowers infarct size.
M27	NEJM: Prognostic value of coronary artery calcium content confirmed in large study.
M25	Archives study emphasizes heritability of early-onset hypertension in men.
M16	Blood vessel protein Robo4 reverses diabetic and age-related macular degeneration in mouse model.
M15	PR, QRS, and QT intervals on ECG are increased in apparently normal elderly persons over age 80.
M13	CMS: Medicare will continue to pay for CT cardiac scans for coronary artery calcification detection.
M12	New macrophage-related protein implicated in inflammatory disease.
M10	Mutated thrombin enzyme may be useful to treat heart attacks and strokes.
M07	Angiotensin vaccine moderately effective in lowering blood pressure
M06	7th Annual Prevention in Renal Disease Conference, Toronto, Sept. 19-20, 2008.
M04	Activating PPAR-delta suppresses inflammation in vascular tissues.
M04	Retinopathy may begin at lower blood glucose levels than expected.
M04	CAPON gene linked to QT interval and heart rhythm abnormalities.
F27	African American teenagers show a high prevalence of microalbuminuria.
F27	Up to 20% of persons taking aspirin show no effect on their platelet function.
F26	Heart attack rates fall in France following institution of national smoking ban in public places.
F26	FDA: Medication guide must be given to patients with each rosiglitazone (Avandia) prescription.
F23	New techniques for detecting air bubbles in blood vessels.
F21	Study suggests that Medicare part D patients use more cardioprotective drugs after MI and live longer.
F21	Salt-rich diet linked to obesity in children via sugar-containing soft drink consumption.
F20	New study confirms increased risk of kidney failure and mortality with aprotinin.
F15	Level of airborne particulates affects microvascular function.
F13	India in the middle of a catastrophic smoking epidemic
F13	University of Groningen study (PREVEND) emphasizes utility of treating hypertension in proteinuric patients.
F13	Genomic studies suggest that CETP (cholesteryl ester transferase protein) mutants protected against coronary effects of cigarette smoking.
F12	New blood test claims to identify pre-eclampsia reliably.
F12	Nocturnal noises raise blood pressure in sleeping subjects.
F11	Declining coronary artery disease rates made a U-turn in 2000, and now are rising.
F11	Reversible, but substantial, memory problems in a subset of women taking Lipitor.
F11	Very high Ang II levels found in chorionic villi of women with pre-eclampsia.
F09	Paradigm shift: Non-osmotic, inflammation-generating accumulation of sodium in the skin
F09	Death of waitress after acute asthmatic attack on entering workplace full of cigarette smoke.
F09	Calcium channel blocker treatment for HTN associated with 23% lower risk of Parkinson's disease.
F06	More on the halted NHLBI diabetes trial arm. Role of rosiglitazone use in the intensive treatment arm unclear.
F06	Beetroot juice found to lower blood pressure because of its high nitrate content.
F05	Richard Lifton, pioneer in the genetics of hypertension, receives Wiley Prize
F01	FDA warns about depressed mood, suicidal ideation in patients taking smoking cessation drug Chantix (varenicline)
J31	Sweetened soft drinks and fruit juices linked to increased risk of gout in men.
J29	Intravascular thrombolytic therapy effective against deep vein thrombosis.
J29	Diuretics produce better outcomes than other anti-hypertensive drugs in treating metabolic syndrome.
J25	Cox-2 inhibitors can cause arrhythmias by affecting potassium channels in the heart.
J22	Aspirin resistance increases risk of heart attack or stroke.
J16	Calcium supplements raise risk of heart attacks and stroke in elderly women.
J13	Pumping rat heart created by seeding a scaffolding with baby rat myocytes.
J09	Higher cholesterol levels linked to improved muscle mass with exercise in the elderly.
J09	Cannabinoid receptor blocking drug effective in causing weight loss.
J08	Risk of cardiovascular events markedly increased when 25-D levels below 15 ng/mL.
J07	Oxygen meter molecule, PHD1 knockouts survive hypoxia - potential application to early transplant viability, heart disease
D27	Aspirin increases liver enzymes in patients taking flutamide for prostate cancer.
D26	Triglycerids and non-HDL cholesterol linked to risk of stroke.
D25	Higher levels of HDL in diabetes may inhibit NO via myristic acid binding - outcome effects unknown.
D17	Drug that stimulates thyroid hormone beta receptors effective in lowering LDL cholesterol
D14	January JASN paper reports that PROActive (pioglitazone) associated with lower CV mortality in diabetics.
D12	More heart risks identified for Avandia.
D11	Physicians unaware of guidelines to treat patients with CV risk factors and metabolic syndrome.
D04	Different anticoagulant regimens after percutaneous coronary intervention yield identical results.
D04	Waistline growth on high-carb diets linked to liver gene.
D04	Renin-angiotensin linked to obesity and insulin-resistance in a gene knockout animal model.
N27	Glucose-insulin-potassium infusion after ST-elevated MI increases risk of heart failure.
N26	MRI documents second-hand smoke injury to the lungs.
N26	Nitrosyl cobamide shows promise as an NO-donor type of drug for hypertension or heart disease.
N12	Interleukin-1 receptor blocker rilonacept effective in treating chronic gouty arthritis.
N09	Simplified anti-hypertensive drug protocol seems to be more effective than more complex approach.
N08	MMWR: CDC reviews smoking prevalence in the U.S., and the results are not good.
N08	Skeletal muscle damage due to statins may operate through atrogin-1 and thus may be preventable.
N08	New nonsteroidal natriuretic hormone identified in human urine.
N07	Perioperative beta-blocker therapy shows mixed results in large RCT.
N07	Simvastatin, but not pravastatin, associated with sleep disturbances.
N07	Prazosin appears to block some glucocorticoid effects.
N07	AHA 2007 Scientific Sessions newsletter - Nov 7th.
N06	AHA 2007 Scientific Sessions Newsletter - Nov 6th.
N06	AHA 2007 Scientific Sessions Newsletter - Nov 5th.
N06	AHA 2007 Scientific Sessions Newsletter - Nov 4th.
N05	Large VA study identifies seasonal difference in blood pressure.
N03	Metabolites of flavonoid (quercetin) present in onions found to be anti-inflammatory.
N02	U.S. AHRQ releases report claiming equal efficacy for ACE-I vs. ARB in controlling blood pressure.
N02	WNK kinases identified as key regulators of blood pressure.
O25	Bayer issues additional guidance to physicians about Trasylol (aprotinin).
O25	Genzyme launches cholesterol-binding drug (Cholestagel) in Europe for patients with primary hypercholesterolemia.
O25	Uvulopalatopharyngoplasty may help some patients with obstructive sleep apnea.
O23	Global extent of obesity epidemic in the news.
O22	Chewing gum shown to help curb appetite and reduce cravings.
O19	Sudden hearing loss associated with erectile dysfunction drugs.
O12	Is fructose really that bad?
O12	Statins help preserve lung function during aging.
O08	FDA to warn of ultrasound cardiac imaging drug risks
O03	Mini-strokes (MRI study) linked to higher uric acid levels.
S25	New, synthetic version of heparin is patented.
S21	Study links TGF-beta and cholesterol to progression of atherosclerosis.
S20	Thiazide diuretics exacerbate fructose-induced metabolic syndrome.
S20	Post-reperfusion heart damage largely prevented by hydrogen sulfide.
S12	JAMA paper shows no benefit of lowering homocysteine in CKD
S10	Protein carbamylation, reflected by homocitrulline levels, strongly associated with atherosclerosis.
S07	Low vitamin D levels during early pregnancy associated with a fivefold increase in risk of pre-eclampsia.
S06	FDA approves first generic versions of carvedilol (Coreg).
S05	New ESC-ESH hypertension treatment guidelines from ESC 2007 (webcast)
S03	European Society of Cardiology 2007 meeting: Clinical Trials Updates
A27	Obesity rates climb in most states.
A27	Patient implanted with baroreceptor stimulating devise to treat refractory hypertension.
A22	Celecoxib - may reduce stent restenosis - overall safety in heart disease still remains to be deteremined.
A22	Hypertension frequently underdiagnosed in adolescents.
A22	Lack of benefit of vitamin E on heart disease may have been due to underdosing.
A20	Mechanism of adenovirus-induced obesity clarified.
A17	FDA warning letter issued emphasizing pharmacogenomic variability in warfarin metabolism among patients.
A13	New study confirms that vitamin C, E, and beta carotene, singly or in combination, of no benefit in heart disease patients.
A10	New research shows skeleton to be an endocrine organ via osteocalcin.
A08	Annals: New study questions the increased heart attack risk with Avandia; original NEJM meta-analysis claimed to have been flawed.
A06	Trial of anti-hypertensive therapy in the very elderly, more than 80 years of age, stopped early because of positive results.
J26	Diesel fume pollution linked to arterial inflammation and atherosclerosis.
J25	Obesity spreads among friends, study concludes.
J24	Soft drinks, including diet soft drinks, linked to 50% higher risk of metabolic syndrome.
J20	Cancer risk linked to CT scan for cardiac calcification (JAMA paper) in the news.
J19	Large VA study shows 50% reduction in Alzheimer / Parkinson risk with simvastatin, but not other drugs in the same class.
J19	Weight loss pill rimonabant associated with increased suicide risk.
J13	Scleroderma Outlook Improves as Survival Increases
J12	Hydroxychloroquine (Plaquenil) may be protective against developing type 2 diabetes.
J12	Serum levels of retinol-binding programs indicate level of visceral fat.
J12	Viagra may save lives in patients with pulmonary hypertension.
J11	Modified herpes virus keeps arteries free-flowing following procedures
J09	CCJM: A different approach to resistant hypertension, emphasizing hemodynamics and the physical examination.
J05	Alteplase may have pro-inflammatory effects - mitigated by cromoglycate.
J05	High sodium in many sandwiches in the news.
J05	Dark chocolate lowers BP slightly, raises levels of nitric oxide.
J02	How stress and high-calorie intact interact to increase weight and change body fat distribution.
J29	Particulates released during renal artery angioplasty can impair kidney function.
J22	FDA clears "computerized medication box" (EMMA) for U.S. market.
J19	FDA approves ambrisentan for treatment of pulmonary artery hypertension.
J19	Hypertension vaccine against angiotensin II shows positive results.
J15	Europ Soc Hypertens releases new, updated hypertension treatment guidelines.
J13	Link between restless legs syndrome and hypertension discovered.
J11	Isradipine slows Parkinson's disease development in mice
J07	New compound similar to aMSH, causing satiety, may be effective in controlling weight in the obese.
J07	Lipid chaperone protein ap2 may be a key to type 2 diabetes and its complications.
M31	Link between mercury and vascular disease involves phospholipase D.
M25	NEJM: Full text of meta-analysis that found an increased risk of myocardial infarction with rosiglitazone.
M25	Non-caffeine components of coffee lower serum uric acid levels.
M21	FDA issues safety alert for Avandia (rosiglitazone) over possible increased heart attack risk.
M21	Statins might have a role in management of hepatitis C.
M17	MMWR publishes regional stroke incidence data for the United States (2005)
M17	Debunking the slavery hypothesis of African American hypertension
M14	Effect of polyphenols (from apples, onions, green tea) on fat catabolism.
M14	Study shows unsuspected immunomodulatory effects of glucosamine.
M07	Liver, kidney damage in people taking large amount of green tea polyphenol supplements.
M07	Centrally acting ACE inhibitors may cut dementia risk in the elderly.
M07	Inactivation of ACAT2 enzyme protects fat-eating mice from atherosclerosis.
M04	Common gene variation associated with markedly increased risk of heart attack.
M03	Nicotinamide riboside, found naturally in milk, dramatically extends lifespan in yeast via sirtuins.
M02	Study highlights gender differences in susceptibility to kidney injury.
M01	Antithrombotics (e.g., aspirin) increase hemorrhagic stroke risk in the elderly.
A30	Activating PPAR-delta may burn fat and reduce metabolic syndrome risk.
A24	AGEs and food preparation may play an important role in chronic disease.
A20	New BMJ study on adverse effects of higher salt intake in the news.
A19	Fewer heart patients need antibiotics prior to dental procedures.
A18	Animal study suggests that changing to a low-fat diet can induce stress.
A15	JAM-1 protein acts in the brain to cause hypertension.
A07	Arthritis patients with CVD who take ibuprofen plus aspirin may greatly increase their cardiac risk.
A05	Think that eating only once a day will make you lose weight? Nope.
A05	Hatfield-McCoy family feud may be linked to bad temper due to heritable pheochomocytomas.
A02	High-prevalence hemachromatosis gene linked to increased risk of stroke.
M30	NEJM: Torcetrapib markedly elevates HDL cholesterol, but shows no benefit
M27	Implanted carotid artery baroreflex stimulator lowers BP by 16-20 mm Hg.
M27	New blood thinner may work without bleeding risk
M26	Drugs work as well as stents, study finds.
M26	Tolvatptan improves signs and symptoms in patients with CHF.
M26	Nesiritide safety trial shows neutral effect on mortality in CHF patients
M26	American College of Cardiology Annual Meeting March 24-27: Monday (26) Newsletter (.pdf)
M26	American College of Cardiology Annual Meeting March 24-27: Sunday (25) Newsletter (.pdf)
M26	American College of Cardiology Annual Meeting March 24-27: Saturday (24) Newsletter (.pdf)
M21	Long-term cessation of smoking may reverse arterial stiffness.
M19	Minisub developed to explore the interior of an arterial blood vessel.
M16	Fructose linked to deranged liver metabolism in rats, involving PPARs, leptin, and metabolic syndrome.
M16	Phthalate exposure linked to metabolic syndrome
M16	Chiropractic adjustment of C1 (atlas) markedly lowers blood pressure in randomized controlled trial
M16	Increased angiotensin 1-7 levels after ACE-I treatment may inhibit lung cancer
M16	Chest compressions without mouth-to-mouth better for out-of-hospital cardiac arrest
M16	An apple a day really does keep the doctor away.
M06	FDA approves aliskiren for treatment of hypertension.
M05	Dietary copper in the news after copper supplementation helps prevent heart failure in stressed rodents.
M05	Atkins diet may be the most effective with few obvious adverse effects
F28	Nifedipine found to mobilize liver iron stores in an animal model of hemochromatosis.
F26	Garlic powerless against cholesterol.
F22	Blood pressure across countries linked to level of happiness of its inhabitants.
F21	Apolipoprotein C1 linked to obesity and type 2 diabetes in American Indians.
F19	Relationship between circadian rhythm clock and blood pressure identified.
F19	CRP liver protein induces hypertension.
F16	MMWR reports on geographic variation in prevalence of heart disease in the U.S.
F14	Neutrophil-derived peptidase enzyme found to be a key player in development of aortic aneurysms.
J30	Need a new aortic valve? No problem. We'll put one in percutaneously.
J30	One third of young people who died suddenly and inexplicably had genetic arrhythmic heart defects.
J29	Health benefits of fruits and vegetables apply to their juices as well.
J29	Major link in brain-obesity puzzle found.
J27	Stroke victims who suddenly lost the urge to smoke identify brain addiction region.
J22	Surprising beneficial effects of losartan on muscle in mouse models of muscular dystrophy or Marfan syndrome
J19	Nintendo Wii videogame use promotes weight loss (n=1).
J17	Strong association between low LDL levels and Parkinson disease identified in small study.
J17	Interesterified fats being used to substitute for trans-fats, but new study shows that they are unhealthy, also.
J16	DNA test to be used to determine warfarin dose.
J15	Pancreatic-polypeptide containing chewing gum - a new potential weapon against obesity
J15	New gene linked to Alzheimer disease
J09	Milk appears to eliminate the cardiovascular benefits of tea
J02	Higher serum uric acid levels associated with cognifitve impairment in the elderly.
J02	Twenty-five best dieting tips ever
J02	Moderate alcohol consumption in hypertensive men associated with lower risk of heart attack.
D27	Green vegetables may lower blood pressure via nitrates.
D20	Friendly microbes could make you fat: Bacteroides vs. Firmicutes
D13	Garlic: Good against vampires, but little protection against cardiovascular risk.
D12	Diet resulting in 10% body weight loss leads to measurable loss in bone density over 1-year period.
D12	Man eats pastrami and cheesecake, has heart attack, sues Atkins company, unsuccessfully.
D11	FDA proposes rules overhaul to expand access to experimental drugs.
D10	MRI scan used to quantify visceral fat.
N29	Procyanidins identified as cardiovascular protective agents in wines; French, Sardinian wines have the most.
N28	Folic acid, homocysteine, and cardiovascular disease: (Full text article in BMJ)
N28	Meta-analysis published in BMJ supports folate supplementation to reduce heart disease risk.
N27	Statin use in otherwise healthy people of dubious benefit.
N27	Richard Lifton honored by two medical societies for work on hypertension.
N27	Gene linked to wet form of macular degeneration.
N26	HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts
N16	Reanalysis of TNT study presented at AHA: Suggests high-dose atorvastatin lowers stroke, CV risk in CKD patients.
N14	Results of TROPHY prehypertension study suggesting benefit of candesartan are questioned.
N14	Fat cells stimulate the adrenal glands to secrete aldosterone: obesity - hypertension link?
N14	NEJM: No survival benefit to angioplasty done 24 hours after myocardial infarction.
N13	American Heart Association Scientific Sessions daily news: Tuesday, Nov 14
N13	American Heart Association meets in Chicago: Monday, Nov. 13 news (pdf)
N13	American Heart Association meets in Chicago: Sunday, Nov. 12 news (pdf)
N13	Pioglitazone reduces progression of atherosclerosis in diabetics
N11	Link between low systolic blood pressure and poor outcome in heart failure patients highlighted in nonuremics.
N07	Why do we eat mindlessly and what would induce us to stop?
N06	Lipoic acid may retard vascular stiffening, aging, via ceramide and phosphatases.
N06	Children's belly fat increases by more than 65% since 1990.
N02	Study shows strong link between serum uric acid levels and hypertension in African Americans
N02	Life saving pump lets heart heal
O30	UT Southwestern looking for patients with severe CHF for optimizer device study.
O25	Human tests underway on intravascular stents that dissolve.
O23	FDA approves once-a-day Coreg (carvedilol) CR for 3 cardiovascular indications
O18	Benefits of eating fish outweigh the risks
O12	Get on scale daily to keep off lost pounds.
O11	Most decaffeinated coffee contains substantial amounts of caffeine
O03	Benefits of ultralow LDL cholesterol targets (70 mg/dL) questioned.
S26	H2-blocker (famotidine) appears to have a beneficial effect in heart failure.
S18	Low blood levels previously thought to be safe linked to risk of CV death
S18	ESRD patients with implantable defibrillators at higher risk of arrhythmia.
S14	MMWR documents rising tide of obesity in the United States.
S14	Pioglitazone shows benefits in terms of cardiovascular outcomes.
S13	More bad news in JAMA paper about CV and kidney risks of COX-2 inhibitors and NSAIDS
S12	New class of pain relievers may help, not hurt, the heart
S11	Want to fight fat? Eat brown seaweed!
S07	Pre-eclampsia breakthrough hope (NEJM)
S05	Pioglitazone reduces secondary stroke risk by 50%.
S05	Carbon monoxide cytoprotective effect may explain lower risk of pre-eclampsia in smoking moms.
S05	U.S approves humanitarian use of Abiocor permanently implanted total artificial heart.
S05	Good one-year control of BP with aliskiren (Rasilez) presented at World Congress of Cardiology
A21	Red and white wine may be equally good for the heart
A18	Role of BMI as a measure of obesity and cardiovascular risk questioned.
A18	Genetic clues to cardiomyopathy and sudden death found in mice - emphasis on the right ventricle
A18	CDC: New U.S. blood lead survey data results: prevalence of elevated blood lead levels slowly improving.
A17	FDA approves use of clopidogrel for ST-segment elevating MI treated medically.
A08	Duke randomized trial favors Atkins style diet over low-fat diet.
A02	Gout increases the risk of heart attack
J31	Scripps research scientists test anti-obesity vaccine
J28	Nanotech used to concentrate angiostatin-like drugs in vascular plaques.
J25	Digitalis relatively safe treatment for diastolic heart failure.
J20	Mayo Clinic researchers discover a genetic cause of atrial fibrillation.
J15	Retinal blood vessel width may be a good indicator of coronary artery disease risk.
J29	NHLBI offers DASH diet eating guide
J28	UK NHS recommends against beta-blocker use for initial treatment of hypertension.
J22	New fat-burnng gene linked to metabolic syndrome.
J20	AHA issues new dietary recommendations; saturated and trans-fat intakes further limited
J16	CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!)
J14	Feeding monkeys a high trans-fat diet markedly adds to abdominal fat.
J08	Benefits of potassium-enriched salt on CV mortality in elderly men
J07	Congenital malformations with first-trimester ACE-inhibitor therapy.
J05	Isis Pharma gets orphan drug status for familial hypercholesterolemia drug.
J05	International trial to see whether or not niacin can prevent heart attacks and strokes
J02	Heart attack risk with COX-2 broadened to include most NSAIDs
M30	It's the magnesium, stupid!
M24	Gum-disease bacterium can infect human arterial cells - is this the hypothesized periodontitis - CVD link?
M22	Study suggest that thiazides may have an adverse effect on CRP.
M22	Trandolapril / verapamil lowers risk of diabetes in Hispanic patients
M22	Ethanol- and smoking-induced upper digestive tract cancers linked to acetaldehyde; preventable via oral l-cysteine
M18	QTc interval and magnesium deficiency: Treatment with Mg Lactate
M17	Chocolate good? Coffee is too! Enjoy.
M15	75% of Irish taxi drivers have hypertension
M15	Moderately increased BMI in the elderly associated with reduced mortality
M15	Tacrolimus-derivative drugs protect animal brains against stroke-induced damage.
M13	Up to 40% of hypertensives in China have diabetes.
M13	FDA approves novel medication (varenicline) for smoking cessation
M11	Common (15%) gene variant affecting fatty acid breakdown increases CAD risk by 50%.
M05	Coffee consumption not associated with heart disease risk.
M03	Diuretics more effective in preventing heart failure in hypertensives when used as first-line drug.
M03	Mayo: 20 g sodium, 50% saturated fat diet improves BP, lipids in obese.
M01	Obesity rates in the U.S. underestimated by 50% due to inaccurate patient self-reporting.
M01	Common nerve cell gene plymorphism linked to QT interval changes, sudden death.
A28	Magnesium deficiency and metabolic syndrome re-emphasized
A28	Does chamomile tea interact with warfarin?
A26	FDA approves first generic pravastatin.
A25	Fatty acid binding protein aP2 gene variant associated with atherosclerosis, type 2 diabetes, in humans.
A25	Anti-oxidant selenium offers no heart disease protection in first large randomized controlled trial.
A19	An integrin-family platelet receptor found to be defective in thrombasthenia, with general implications for blood clotting.
A13	CNTF can overcome leptin resistance to fight obesity.
A08	AMBI (Tarrytown company) gets exclusive rights to Finland's PANSALT distribution in the U.S.
A08	Losartan can prevent progression of Marfan syndrome (in mice) via inhibition of TGF-beta
A04	Epicardial fat and adipocytes around coronary arteries may contribute to CAD.
A04	Lack of sleep linked to hypertension risk
M30	Manipulation of intracardiac catheters by externally applied magnetic fields to cure a. fib.
M30	Apparent CV protective effect of alcohol intake may be due to a statistical fluke.
M24	Study focuses on bread as a major cause of higher salt intake.
M24	Benefits of eating oily fish seem to be slip-sliding away.
M17	Virus blamed for obesity epidemic.
M16	Glycemic index is bupkus.
M15	Specially formulated salt substitute cuts hypertension.
M14	ACC Scientific Meeting, Atlanta: Tuesday, March 14th Newsletter (.pdf)
M14	ACC: Early treatment of pre-hypertension may postpone onset of true hypertension
M13	Diuretics, and especially, K-sparing diuretics, markedly lower risk of Alzheimer's disease.
M13	American College Cardiology Meeting: Monday, March 13th newsletter (.pdf)
M13	High dose statin therapy causes regression of coronary atherosclerosis.
M13	High-dose atorvastatin (Lipitor) improves kidney function in CKD patients in large clinical trial.
M13	Another take on B vitamins, homocysteine, and vascular risk.
M13	NEJM: B vitamins for homocysteine lowering: Fewer strokes, but more unstable angina.
M13	NEJM: Homocysteine lowering by B-vitamins of no benefit post MI - trend toward increased risk.
M13	American College of Cardiology (Atlanta) Sessions: Sunday highlights. (.pdf)
M13	American College of Cardiology (Atlanta) Sessions: Saturday highlights. (.pdf)
M13	NEJM study casts doubt on efficacy of Plavix over aspirin - and higher bleeding risk cited.
M10	Blood pressure is falling globally, and no one knows why!
M10	Major WHO study concludes calcium supplements can reduce severity but not incidence jtd of preeclampsia.
M08	Diabetes drug Byetta (exenatide) gaining attention as weight loss aid.
M07	Heavy coffee drinking plus gene variant tied to heart attack risk in Costa Ricans
M03	Serotonin may play a role in hardening of the arteries.
F28	Stress may trigger heart attacks by increasing number of blood platelets.
F22	Genetic tests developed to test for salt-sensitivity of blood pressure.
F20	Mars chocolate maker to introduce foods with flavonol-rich chocolates.
F17	Fat in liver connected to high blood pressure risk.
F12	WHO report identifies relatively high hypertension rates in males from India.
F10	IU scientists using stem cells to treat severe peripheral arterial disease.
F10	Blood levels of aldosterone linked to preservation of hearing with aging.
F07	Low fat diet benefits for women less than expected.
F05	Basic gender difference identified in coronary artery disease.
J31	AHA Scientific Statement: Dietary approaches to treat hypertension
J30	Certain adenovirus infections linked to obesity on animals and humans
J28	FDA approves first ever inhaled insulin for the treatment of diabetes.
J26	Aprotinin (Trasylol) linked to increased risk of kidney failure, heart attack and stroke.
J24	Alagebrium (a collagen cross-link breaker) softens arteries - and that's good for you.
J24	Study of Kuna indians is good news for chocoholics - procyanidin in cocoa lowers BP.
J23	Fermented milk drink reduces high blood pressure.
J23	Fetal form of toponin I, with a histidine for alanine substitution, has cardioprotective effects.
J22	AHA review casts doubt on cardiovascular health benefits of soy-based foods.
J21	British study shows that work stress linked to both heart disease and metabolic syndrome.
J19	Heart-healthy compound in chocolate identified - it's epicatechin.
J17	Aspirin protects men against myocardial infarcts and women against ischemic strokes.
J17	US FDA considering two new drugs that fight obesity.
J17	Activated blood coagulation factor VIIa under study to treat intracerebral hemorrhagic stroke.
J16	Tomato extract seems to have a large effect on lowering blood pressure.
J16	Annals: More exercise associated with 30-40% reduction in risk of dementia.
J15	Acetazolamide reduces sleep apnea severity in heart failure patients.
J15	Hypothalamus has a fatty acid sensor that may regulate food intake
J12	Caloric restriction appears to make the heart more elastic.
J10	Mid-life obesity increases mortality and cardiovascular risk.
J09	Smoker? Drink tomato juice (or drink bloody Marys) to ward off emphysema.
J04	Adenosine receptor antagonist completes phase 2 trials for congestive heart failure.
J02	UCSF study in Annals suggests that obesity increases risk of kidney failure.
J02	U.S. weighs obesity surgery options
D28	Researchers discover molecular link explaining why high-fat diet can cause type 2 diabetes.
D27	Do low birth weight babies like saltier food? Study on birth weight stirs up salt wars.
D26	Diabetes, CHF home patient monitors taking off in the UK.
D23	JAMA: Air pollution and high-fat diet combine to cause atherosclerosis in mice.
D20	Allergic reactions from drug-eluting stents
D15	Both BNP and NT-proBNP useful to deteck CHF in persons with CKD.
D07	Fructose may be cause of obesity epidemic; also raises uric acid.
D05	Heparin antibodies pose risk in heart surgery patients.
D03	Random testing shows high lead levels in some imported Chinese plums.
D03	CV benefits of lower intakes of alcohol called into question.
N29	Why trying to make couch potatoes exercise may be difficult.
N29	New AHA CPR guidelines: 30:2 compressions, cooling to 90 degrees.
N29	Fatty liver being seen increasingly in obese patients.
N28	High-carb diet linked to diabetic hypertension.
N28	Nabi's nicotine vaccine shows promise in helping smokers quit.
N24	Osteoporosis associated with six-fold increase in risk of heart disease.
N23	Sweat is a good indicator that a heart attack may be coming.
N22	Percutaneous laser myocardial revascularization no better than placebo.
N22	AHA: Late-breaking clinical trial abstracts (.pdf)
N21	Roller coaster rides can provoke arrhythmias.
N19	Researchers zero in on possible viral cause of Kawasaki disease.
N17	AHA: CV mortality benefits of diuretics linked to alpha-adducin genotype.
N16	Low-carb diet better than low-fat for improving metabolic syndrome.
N16	Collagen crosslink breaker alagebrium can soften arteries.
N16	AHA: Autologous stem cell infusions show promise in severe CAD.
N16	AHA: Aliskiren (renin inhibitor) adds to anti-HTN effects of irbesartan.
N16	Drinking decaffeinated coffee increases pro-atherosclerotic ApoB levels.
N16	Trichostatin may reduce premature atherosclerosis in lupus patients.
N16	High HDL level is pro-atherosclerotic in lupus patients.
N16	Pioglitazone reduces heart attack rate in type 2 diabetics by 28%.
N16	AHA meeting in Dallas: Wednesday newsletter.
N15	GRK5 involved in arterial restenosis lesions.
N15	AHA Meeting in Dallas: Tuesday daily newsletter (.pdf)
N15	AHA Meeting in Dallas: Monday daily newsletter (.pdf)
N13	AHA Scientific Sessions open in Dallas: Sunday daily newspaper.
N12	Risk-stratified analysis proposed to analyze RCTs to detect harm.
N12	Statins overcome learning disabilities in mice with neurofibromatosis 1.
N10	Fizzy cola consumption associated with HTN in women.
N09	No link between coffee drinking and hypertension in women.
N06	New FDA-supported website lists latest approved drug labels for all meds.
N05	Waist-hip ratio better than BMI to predict CV risk.
N01	Diabetic blacks have less coronary artery disease than diabetic whites.
O28	Botox injections effective in treating stroke spasticity.
O28	Air pollution linked to ischemic stroke risk.
O28	HDL cholesterol involved in immunity against parasites.
O27	Bone marrow stem cells may help heal hearts years after heart attack.
O27	JASN Express: Pravastatin lowers CV death risk in diabetics with CKD.
O26	ASN Renal Week 2005 abstracts now available on-line.
O25	Got high BP? Just zap your PAG - but make sure it's the front part!
O23	JAMA: Increased mortality after bariatric surgery.
O23	JAMA: Article detailing CV risk increase with Pargluva (muraglitazar)
O19	Lancet study questions efficacy of beta-blockers for hypertension.
O18	Role of prolonged bedrest to manage hypertension in pregnancy questioned.
O18	Researchers closing in on Na-K-ATPase inhibitor hormone; role in preeclampsia?
O17	Dopamine receptor gene found to play a role in blood pressure inheritance.
O16	JAMA: Cholesterol levels in U.S. inhabitants continue to drop.
O11	Fatty foods can fight inflammation, induce satiety, via CCK.
O11	Surgical menopause can trigger salt-sensitive hypertension.
O11	Microsvascular changes in the retina linked to strokes, even with normal BP.
O11	Study questions measurement of C-reactive protein to assess cardiovascular risk.
O10	RBC secretion of s-nitrosothiol regulates vascular (esp. pulmonary) tone.
O09	JASN: Glycosylated Hb in non-diabetic CKD pts. increases mortality risk.
O09	Hypertension prevalence 25% or higher in middle-aged Beijing residents.
O09	SEPS 1 gene on chromosome 15 plays key role in inflammation.
O07	Lancet: Pioglitazone lowers risk of heart attacks and strokes in diabetics.
O06	Soy compound, genistein, found to inhibit amyloid plaque formation.
O05	Generic form of amlodipine approved by the FDA
O04	Addition of amiloride to HTN drug regimens helps, esp. in African Americans.
O04	90% of Framingham cohort over 60 years of age now overweight.
S28	Toprol (metoprolol)/Topamax/Tegretrol look-alike names prompt FDA alert letter.
S28	beta-2-adrenergic receptor genetics determines survival after MI.
S26	AHA issues dietary recs for children and adolescents.
S26	Lancet study suggests wider use of statins in higher dosages may be beneficial.
S26	Smoking appears to double the risk of developing type 2 diabetes.
S26	Lead exposure plus high blood pressure may impair mental ability.
S25	Genes on chromosome 2 linked to resistant hypertension.
S23	Panic disorder may increase risk of coronary artery disease.
S22	NEJM: Efficacy of various strategies to raise HDL cholesterol.
S22	Surprisingly high cancer, heart death rates in 1-4 cig/day smokers.
S20	Novartis oral renin inhibitor aliskiren shows good results in phase III trial.
S17	Fat cells linked to production of CRP via resistin.
S13	Pioglitzaone improves cardiovascular outcomes in diabetics.
S13	Low-dose aspirin might protect against cardiac effects of COX-2 inhibitbors.
S09	MMWR: Cholesterol screening rates increasing, but only modestly.
S06	Eur Soc Cardiol 2005 Congress website
S06	CV outcomes better with amlodipine / perindopril than with atenolol / diuretic.
S06	Calcium scans can predict heart disease in healthy men.
S06	ESC 2005: Fondaparinux safer than enoxaparin, and as effective
S06	Soy protein-rich diet may help prevent fatty liver of diabetes.
S06	Folic acid, B vitamins lower homocysteine, but show no heart protective effects.
S01	JCI: New kidney hormone identified that metabolizes catecholamines.
A29	Coffee is number one source of antioxidants in U.S. diet.
A29	Prompt statin therapy after heart attack cuts mortality risk in half.
A26	Metabolic syndrome doesn't exist, diabetes groups claim.
A24	TFAH releases report on obesity in America - we're all getting fatter.
A24	The American Society of Hypertension ditches AmJH for JCH.
A22	Scios announces recommended use initiative for Natrecor.
A19	Research promising for chocolate lovers.
A19	Jury awards widow 253 million in Vioxx suit against Merck.
A19	Myogen announces phase 2 trial results of darusentan in resistant hypertension.
A17	Bluetooth scanner stroke hope.
A16	Analgesic drug use linked to high blood pressure in women.
A16	After overeating we don't compensate by eating less.
A16	PLEKHA1 gene linked to age-related macular degeneration.
A13	NEJM: Retinoid X receptors - new targets to treat metabolic syndrome.
A11	Following clinical guidelines in elderly can lead to polypharmacy.
A09	Modified form of digitalis finds role as a cancer killing drug.
A09	Salt restriction lower BP and urine protein in Blacks.
A04	Prehypertension triples heart attack risk.
J28	JASN: ADMA strongly predictive of CKD progression
J28	Propanolol may be useful in erasing traumatic memories in PTSD patients.
J25	Cocoa flavonoids: Eat two chocolate bars and call me in the morning.
J25	How estrogen via its alpha receptor may be bad for women's hearts.
J23	TGF beta receptor mutations linked to aortic dissections.
J22	NEJM: Statins had no effect on hard outcomes in diabetic ESRD patients.
J20	JASN early release: Short daily HD lowers LVH by 30%, also CRP.
J19	Annals: If Medicare were to provide ACE-I for free, it would be cost effective.
J19	Natrecor (nesiritide) safety summary (Scios)
J19	ALLHAT suggests that diuretics rule, even in Blacks with metabolic syndrome.
J19	Dark chocolate and blood pressure in the news (watch the oxalate!).
J17	Mutations in NOTCH1 gene linked to aortic valvular disease.
J17	Faulty ENPP1 gene linked to diabetes and obesity.
J15	Ruboxistaurin reduces vision loss in diabetics with macular edema.
J14	NEJM op-ed piece attacks continued use of nesiritide.
J11	Walking on cobblestones reduces blood pressure, improves balance.
J11	Hageman clotting factor linked to atherosclerosis.
J06	Therapeutic robotics offers new benefits for stroke patients.
J06	Expanding definitions of disease: economic consequences
J06	Vitamin E supps do not protect women from heart attack, stroke, or cancer
J04	Implanted stomach stimulator used as an alternative to stomach-stapling surgery.
J30	Gastric bypass surgery lowers CRP by 50%.
J30	CRP receptor in endothelial cells identified.
J30	ALLHAT subanalysis shows diuretics lower CV risk in diabetics as well as ACEI
J29	Consumer reports announces "best buy" calciuim channel blockers.
J29	Singing exercises for throat muscles target snoring, sleep apnea.
J28	Pfizer review claims no link between Viagra use and blindness.
J26	Gene hunters flock to Amish country.
J24	FDA refuses to approve broader use of Abiomed artificial heart.
J24	US FDA approves BiDil for African Americans with CHF.
J23	AHA: Public access defibrillator study doubles survivals: Policy statements.
J22	Initial FDA review of Abiomed artificial heart is mixed.
J17	FDA advisory panel recommends approval of BiDil for CHF in Blacks.
J17	High levels of ADMA associated with renal disease progression in CKD.
J17	John Laragh raises concern about MD conflicts of interest at the Am Soc HTN.
J17	Study sheds light on why diabetes drugs (thiazolidinediones) cause edema.
J16	BMJ: Should everyone over 50 be taking a daily aspirin?
J14	FDA examines application of BiDil (two vasodilators) to treat CHF in Blacks.
J14	Viagra effective in treating pulmonary arterial HTN in kids.
J13	Highlights from Am Soc Hypertens Meeting (via the ESH)
J13	Compression stockings markedly cut risk of DVT on airplane flights.
J07	Plasma BNP distinguishes restrictive myopathy from constrictive pericarditis
J07	Low vitamin B12 levels common, associated with high homocysteine levels.
J05	Gene therapy reverses pulmonary hypertension
J04	JASN Express: Crit-line blood volume monitoring fails to reduce hospitalizations
J04	CDC defends its position about obesity and increased mortality risk.
M31	Off-pump, on-pump cardiac bypass methods give comparable results.
M27	Adverse impact of second-hand smoke stronger than previously believed.
M25	Atherosclerosis linked to inefficient mitochondria in vascular endothelial cells
M24	Crestor (rosuvastatin) associated with higher adverse event risk.
M24	Higher milk intake associated with lower CV, stroke risk.
M21	Am Soc Hypertension writing group comes up with new definition of hypertension.
M20	American Society of HTN 2005 meeting abstracts
M19	Am J Nephrol: Carnitine therapy associated with decreased hospitalizations
M18	NEJM: Cystatin levels predict mortality better than Scr in the elderly..
M18	Arteriosclerosis Thrombosis Vasc Biology abstracts, 2005 (pdf)
M18	ASH: New onset diabetes 23% higher with amlodipine vs. valsartan.
M12	Animal studies suggest thyroid hormone may help failing hearts.
M12	Active vaccine prevents prion disease from developing in mice.
M10	Am Soc Hypertension focuses on Hispanic hypertension.
M10	Threefold increase in sudden cardiac death from certain non-cardiac drugs.
M09	Pioglitazone reduces carotid artery thickness in diabetics.
M07	Immune gene with 20% prevalence linked to CAD, rheumatism, and MS.
M06	Madison and Montreal researchers study genetics of HTN in French Canadians.
M06	Pegaptanib shows promising results in treating diabetic macular edema.
M05	Overexpressing catalase in mice mitochondria extends lifespan by 20%.
M03	Consumer Reports website suggest Best Buys for ACE inhibitors.
M03	Schelling paper that is the basis for the dipstick protein-SC calculator
M03	Schelling-Case Western dipstick proteinuria/specific gravity calculator.
M02	Is it raining nanobacteria and if so, is this an important health problem?
M02	FGF-21 finds itself as a new therapy for type 2 diabetes.
M02	Transcendental meditation may expand lifespan in 18 year randomized trial.
A29	ACAT2 cholesterol transforming enzyme a key player in atherosclerosis.
A28	Potassium channel gene linked to how much sleep different persons need.
A27	Combo Vytorin (ezetimibe + simvastatin) lower CHO better than atorvastatin alone
A21	Could an adenovirus be responsible for recent epidemic of obesity?
A21	My.pyramid.gov - new U.S. government website with dietary guidelines
A21	Studies in mice tie sleep disturbances to metabolic syndrome.
A20	Obesity death risk overstated; modestly obese have higher survival rate.
A20	Nesiritide associated with an increased death rate in CHF patients.
A18	Melbourne researchers develop safer and more effective "aspirin".
A17	Exercise has trivial effect, and only on DBP, in older adults.
A14	Heart ring fixes two problems at once.
A13	Heart valve ring reverses damage from congestive heart failure, easing symptoms
A11	New gene found in 20% of people may be behind CV-inflammatory syndrome.
A08	New kidney protein 'renalase' - regulates heart contraction and blood pressure
A08	Liver may be source of 'good' cholesterol
A07	Excimer laser angioplasty used to reduce renal artery stent restenosis.
A06	Table of contents for new K/DOQI cardiovascular guidelines
A06