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HDCN News Archive -- Hypertension, CV Disease
Jul02 U.S. obesity problem intensifies.
Jul02 Enalapril or losartan markedly slow progression of eye damage in type 1 diabetics.
Jun30 Genetic study suggests that relationship between C reactive protein and CV disease is not causal.
Jun26 FDA to regulate tobacco.
Jun24 Analysis of large number of bariatric surgery patients shows the procedure to be relatively safe.
Jun19 Clopidogrel may increase risk of death in patients with diabetic nephropathy.
Jun17 Annals: Stents of no benefit in treating renal artery stenosis
Jun13 Higher vitamin D levels associated with successful weight loss in obese subjects on a diet.
Jun05 Aldosterone levels found to be increased in chubby teenage boys.
Jun01 Modified lycopene extract (ateronon) reduces harmful oxidation of fats.
May30 Results from 8 late-breaking clinical trials at Heart Failure 2009
May29 Risks of aspirin outweight benefits for primary prevention of stroke, MI in those with normal kidney function.
May26 Simplified chart may aid in diagnosing hypertension in children.
May25 Search all abstracts from the World Congress of Nephrology 2009
May25 Gene variant found that increases risk of both severe periodontitis and myocardial infarction.
May22 Fenofibrate reduces amputation risk in diabetics.
May18 Heart disease patients who are overweight do better and live longer.
May15 Use of CT angiography in the emergency room to help diagnose chest pain found to be cost-effective.
May15 JASN early release: Low 25-D levels associated with coronary artery calcification progression
May15 High triglyceride levels associated with diabetic neuropathy
May15 Interventional study in mice links cytomegalovirus infection to high blood pressure.
May14 Monotherapy with DARA, an endothelin and angiotensin I receptor antagonist, lowers BP a lot.
May14 ALLHAT follow-up study confirms benefits of chlorthalidone.
May11 UMOD gene, associated with Tamm-Horsfall protein production, linked to kidney disease.
May11 Cyclophilin may play a key role in arterial damage associated with atherosclerosis.
May11 Vitamins C and E block improvement of insulin sensitivity with exercise.
May08 Low BP associated with strokes and MI in patients with coronary artery disease.
May08 Combining dieting with exercise while standing/sitting/kneeling on a vibration plate machine lowers abdominal fat.
May04 8th Annual Prevention in Renal Disease Conference, September 25-26, 2009 in Toronto.
Apr30 Urine screening test seems to predict presence of atherosclerotic disease.
Apr26 Statins may reduce prostate inflammation and reduce risk of prostate cancer
Apr26 Sodium in prepared foods frustrates attempts to implement low sodium diet in CHF patients.
Apr26 Prostaglandin 2-alpha may be new target for control of blood pressure and atherosclerosis.
Apr23 Low-sodium vegetable juice may help reduce body fat in patients with metabolic syndrome.
Apr22 Alzheimer beta-amyloid can be degraded, and some drugs can increase breakdown rate 7-fold.
Apr18 New stem cell treatment for age-related macular degeneration in development.
Apr17 New discoveries on how collagen activates platelets may lead to new treatments to prevent clotting.
Apr16 Heart risk in diabetics may be exaggerated.
Apr16 Endothelin A receptor antagonist darusentan shows promising results in resistant hypertension.
Apr14 Aspirin and similar drugs associated with brain microbleeds in the elderly.
Apr12 CXCL5, secreted by white adipose tissue, may be the link between obesity and inflammation and insulin resistance.
Apr11 Three papers on brown adipose tissue in this week's NEJM.
Apr11 One thousand 2007-2009 audiofiles and slide/audio talks added to HDCN's 20 topic-related channels.
A07 Chemokine CXCL5, produced by fat cells, linked to inflammation and insulin resistance.
A06 Chlorthalidone increases SNS activity, spironolactone does not
A01 Yeast-powered fuel cells (for implantable devices) derive energy from glucose in human blood.
M30 GNSOR-deficient mice markedly resistant to heart attacks.
M30 Lipoic acid supplements markedly lower triglycerides in an animal model.
M30 AURORA study confirms the 4D study: Statins of no benefit in dialysis patients.
M30 Radiofrequency ablation of renal sympathetic nerve activity results in sustained improvement in refractory hypertension.
M30 NEJM: Ventriculoplasty of no benefit when added to CABG in patients with CAD and heart failure.
M29 Link to slide/audio and audio symposia on HDCN
M29 American College of Cardiology 2009 - Day 3 newsletter
M29 American College of Cardiology 2009 - Day 2 newsletter
M29 American College of Cardiology 2009 - Day1 newsletter
M29 Crestor (rosuvastatin) lowers risk of venous thromboembolism by 34%.
M28 Corking shut the atrial appendage markedly reduces risk of stroke in patients with atrial fibrillation.
M26 AHA supports a lower sodium intake limit (1.5 g Na/day) for most Americans.
M26 Testing for endothelial function using a finger device that evaluates reactive hyperemia linked to CV outcomes.
M26 Preliminary data show potential benefits of catheter-based thrombolysis for stroke.
M26 Cholesterol crystals linked to arterial plaque disruption and heart attack.
M22 Ten genes associated with prolonged QT syndrome and risk of sudden cardiac death.
M22 Correct warfarin dose determined by 3 genes only.
M20 FDA panel gives nod to alternative to warfarin
M18 Another statin (Crestor, rosuvastatin) fails to show a benefit (rumor has it) in dialysis patients.
M17 Endothelial lipase linked to levels of good cholesterol
M12 HDL levels and glucose sensitivity linked to neck circumference.
M12 New anti-clotting compound derived from magnolia trees shows encouraging results in phase II safety study.
M09 Eating fish associated with increased intelligence in Swedish teens.
M04 Reduction of stroke risk associated with green/black tea drinking appears consistent and linear.
F26 Cornell researchers develop and market a point-of-care urinary sodium test strips to monitor salt intake.
F25 NEJM: Randomized trial of 4 different diets (low fat, low CHO, etc.) fails to find a single winner.
F23 Genes controlling atrial natriuretic peptide expression linked to hypertension.
F18 NEJM: Genetic testing helps predict warfarin dose.
F17 Ain't necessarily so series: oxidative stress may prolong, instead of shorten, life (worm study)
F11 Very high doses of candesartan effective in further reducing proteinuria.
F10 Vigorous exercise (running) may reduce the risk of age-related macular degeneration.
F10 American Heart Association focuses on the high risk of stroke in women
F09 LSR, lipolysis-stimulated lipoprotein receptor, found to be deranged in type 2 diabetes with obesity.
F03 Short-term growth hormone treatment attenuates muscle loss after bariatric surgery.
F03 FOXO3A gene variants associated with living beyond 100 in multiple parts of the world.
J30 Epoxide hydrolase inhibitor reduces heart failure in animal model
J30 Sulfenic acid may be reason for potent anti-oxidant effect of garlic.
J30 FDA mandates detailed hyperkalemia warning for Aldactone (spironolactone)
J28 The new study that caused the fuss about clopidogrel and proton-pump inhibitors.
J28 FDA cautions on combined use of clopidogrel and proton-pump inhibitors until more info is obtained.
J26 Animal study suggests benefit of statins in preventing stroke in patients with cerebral cavernous angioma or malformation.
J20 Randomized (DRIP) trial reports benefits of dry weight reduction in dialysis pts. on 24-h blood pressures.
J19 Three new genes linked to childhood obesity identified.
J19 Trial of stem cell treatment to treat stroke patients approved for recruitment.
J19 Indian subcontinent heart disease gene identified.
J17 Heart and Stroke Foundation of Ontario issues "alert" against combined use of ACEIs and ARBs.
J15 Source of endogenous salicylic acid identified as benzoic acid found in fruits and vegetables.
J12 High sodium to potassium ratio in the urine increases cardiovascular event rate.
J09 New anti-anginal drug acts by working on sodium channels.
J01 New Year's Resolution? Quit smoking. American Lung Association support info.
J01 MMWR: Lower acute MI rates after city implements smoke-free ordinance
D29 Study of Amish identifies a new gene linked to sodium control and hypertension
D18 JASN early: First morning urine better than spot urine to detect microalbuminuria
D15 FDA approves premounted renal stent system manufactured by Boston Scientific
D14 Study in the Amish links APOC3 gene mutation, triglycerides, and resistance to heart disease.
D13 New study shows links between 30 genes and cholesterol and triglyceride levels.
D13 Should nephrologists give beta-blockers to their patients with CKD?
D11 CJASN: Rosiglitazone may benefit patient with FSGS
D09 Statins adversely affect placental development in an in vitro model.
D04 NEJM study shows that irbesartan of no benefit to patients with diastolic heart failure.
D04 Liver fat, rather than abdominal fat or shape, may be main cardiovascular risk.
D03 NEJM: ACEI plus amlodipine better than ACEI plus a thiazide in terms of cardiovascular events.
D02 Depression increases risk of subsequent visceral fat gain in longitudinal study.
D02 Consumer Reports investigates sodium content of foods: salt is present where one may not expect
D02 Cardiologists debate NEJM study comparing coronary CT scans with percutaneous angiography.
D01 Canadians publish best practice recommendations for stroke care.
N27 New studies confirm importance of sirtuin pathway in mammalian ageing; attention focuses on resveratrol.
N26 Binge drinking may damage the heart via acetaldehyde activation of macrophages.
N21 Do your CKD patients still smoke? Who is still smoking in the US by state.
N18 New microRNA compound protects mice against heart failure.
N14 Renal Week: Relative vitamin K2 deficiency linked to vascular calcification in ESRD
N13 Catheter thermoablation of atrial fibrillation far superior to drug treatment.
N13 FDA: Review of atrial fib - bisphosphonate data suggests a weak or no relationship.
N11 Sleep apnea associated with increased risk of sudden death.
N11 AHA Scientific Sessions 2008 in New Orleans, LA: Daily News, Nov 8 -12.
N09 Rosuvastatin given to patients with normal cholesterol levels but high CRPs markedly lowers CV risk.
N04 Intraocular anti-VEGF drugs to treat retinal proliferative disoders may have a dark side.
N04 New SIRT1 activating drug may protect against diet-induced obesity.
O30 MYH9 gene variations linked to CKD in African Americans - researchers to present new data at Renal Week 2008.
O29 Grapes protect the hearts and blood pressure of rats fed a salty diet.
O28 VEGF-based screening test for pre-eclampsia foreseen based on new research.
O28 French company develops a next generation totally implantable artificial heart.
O28 Plavix (clopidogrel) may be inactivated by some calcium channel blockers.
O27 Runners burn more calories at rest than sedentary persons, and it's due to changes in the mitochondria.
O27 Risks of irregular heartbeat and atrial fibrillation increased with fosamax and other bisphosphonates.
O27 Pregnant women consuming flaxseed oil have a high (4x) risk of premature birth.
O27 Pentoxifylline lowers proteinuria alone or in addition to an ACE inhibitor.
O23 Hydrogen sulfide may be a key regulator of blood pressure.
O23 European watchdog agency suggests not using diet drug rimonabant due to depression side effects.
O23 New diet drug tesofensine appears to be remarkably effective.
O22 Journal of Renal Nutrition publishes composition of common salt substitutes.
O16 Fructose feeding induces high triglycerides and leptin resistance in rats.
O15 Resveratrol prevents liver fat accumulation in a mouse model of alcoholic liver disease.
O14 Resveratrol found in dark chocolate and cocoa.
O14 B vitamins of no help in slowing progression of Alzheimer's disease.
O13 Book Review: Clinical Guide to Use of Antithrombotic Agents in CAD
O13 Are you nuts about nuts? Nuts! One study fails to shell out any benefit.
O13 A series of abstracts presented at CRF meeting suggesting that triple anti-platelet therapy (adding cilostazol) improved outcomes.
O09 Retinylamine markedly slows age-related macular degeneration in an animal model.
O09 New physical activity guidelies: 30 minutes of moderate exercise 5 times per week;
O08 A single dose of EPO injected after a heart attack can limit apoptosis and thereby reduce heart cell damage.
O07 Farnesyl transferase inbitior (tipifarnib) reverses cardiovascular effects of progeria.
O07 Study illustrates importance of inflammatory macrophages in obesity; insulin resistance reversed by killing these cells.
O07 Even occasional smoking can impair arterial function for a prolonged period.
O07 Complement pathway and the innate immune system implicated in age-related macular degeneration.
O06 One-dollar-a-month polypill containing ASA, thiazide, ACEI, and statin to undergo clinical testing.
S30 Lancet: New genes found that link to gout.
S26 Aptly named horny goat weed found to be a source of specific phosphodiesterase inhibitors.
S25 In humans, as opposed to lab animals, caloric restriction does not lower IGF-1, but protein restriction does.
S22 Darapladib slows atherosclerosis in a pig model.
S22 Secondhand smoke exposure increases risk of peripheral artery disease in women.
S19 High-salt diet contributes very substantially to resistant hypertension.
S18 Are statins ineffective for protection against cardiovascular risks in women?
S18 New mechanism for cardiac arrhythmia discovered.
S18 Listening to Mozart lowers high blood pressure (really)
S16 NHANES data analysis links elevated urine bisphenol levels to diabetes, cardiovascular disease.
S16 Conbining thiazides with potassium-sparing diuretics markedly lowers cardiovascular mortality.
S15 Carvedilol and alprenolol, but not other beta-blockers, stimulate cellular protective pathway in the heart.
S12 Cardioprotective effects of alcohol ingestion may be due to aldehyde dehydrogenase.
S10 NEJM early release: Benefits of tight glucose control persist in type 2 DM at 10 years
S10 NEJM early release: Tight BP control has to be continued in type 2 diabetics; otherwise benefits are not maintained.
S05 Photographing what they eat helps dieters stick to weight-loss plans and identifies bingeing.
S02 Want to live longer? Take the stairs instead of the elevator.
A29 Singh and Furberg editorialize against use of thiazolidinediones due to CV risk and lack of CV benefit.
A29 100g/day of dark chocolate lowers blood pressure by 3 mm Hg.
A27 Debate flares: Can obese patients be healthy?
A26 Allopurinol lowers blood pressure in hypertensive adolescents
A26 Newer gated CT scans diagnose coronary artery disease and obviate need for angiography.
A22 Some evidence that Vytorin is, or maybe is not, associated with an increased cancer risk; FDA gets involved.
A21 AMAG receives fast track designation from FDA for ferumoxytol as an MRI contrast agent.
A19 Lowering homocysteine with folic acid and B vitamins fails to reduce CV events in heart disease patients.
A19 Obesity epidemic due to increased food intake, and not decreased activity level.
A15 When is a potential heart donor really dead? NEJM report raises some ethical questions.
A15 Lancet: ONTARGET study shows mixed results for combined ARB/ACEI therapy; greater reduction of proteinuria but a higher renal event rate.
A15 Bariatric surgery - induced weight loss helps, but does not cure, sleep apnea.
A13 Enhancing lysosomal receptors for chaperone molecules prevents aging of mouse livers.
A12 MicroRNA specific to endothelial cells associated with blood vessel branching, survival after cardiac infarction.
A08 FDA issues warning about risk of rhabdomyolysis when simvastatin is used with amiodarone.
A08 AHA issues recommendations for ambulatory BP monitoring is certain children and adolescents.
A05 IV calcium channel blocker wins FDA approval to treat acute hypertension.
A05 Baroreflex device to treat hypertension. A pipe dream? 200 million dollars raised so far says maybe not.
J31 Two new drugs have profound effects on exercise conditioning in mice.
J30 Does adiponectin have a dark side? Study associates it with increased cardiovascular risk.
J29 New study highlights risk of losing bone density while following a low-calorie diet for weight loss.
J29 Rember, a drug that is really a blue dye that prevents tau tangles, appears to slow Alzheimer's disease.
J29 Testosterone changes associated with perimenopausal increase in metabolic syndrome risk.
J29 Observational study suggests that statins may lower risk of senile dementia very substantially.
J24 Complement activation is increases in patients with age-related macular degeneration.
J24 In acute study, fructose increases lipogenesis relative to glucose.
J23 NEJM: Genetic mutation associated with most patients who develop myopathy on high-dose statins.
J22 Ezetimibe plus simvastatin drug trial shows no effect on aortic valve stenosis progression.
J19 Human blood vessels grown in mice
J17 Genetic variant identified that increases risk of elevated triglycerides fourfold in Asian Americans.
J17 U.S. population keeps getting fatter; esp. Alabama, Mississippi, and Tennessee.
J17 AHA to launch new journal focusing on cardiovascular outcomes trials and methodology.
J16 Doctors hopeful that improved blood thinners are on the horizon: Three new candidates.
J16 Annals: Low molecular weight heparin for 7 days better than stockings after arthroscopic knee surgery.
J12 Pioneering heart surgeon Michael DeBakey dies at age 99.
J10 Histone deacetylase (HDAC) inhibitors protect ischemic tissue from injury.
J08 Farm-raised tilapia fish has relatively low levels of omega-3 fatty acids.
J08 Fish oil plus red yeast lower cholesterol to the same extent as statin therapy.
J08 Overweight patients trying to lose weight lose twice as much if they keep a food diary.
J03 Statins spur glial progenitor cells to develop into oligodendrocytes.
J01 Caffeine intake increases rate at which muscle replenishes glycogen stores after exercise.
J01 Doxycycline-inhibitable protease activity increased in SHR rats; this also may explain various aspects of metabolic syndrome.
J30 AHA publishes cookbook focusing on healthy soul food recipes
J30 Sudden hearing loss associated with increased risk of future stroke.
J30 AHA launches hearthub.org, a website for patients.
J30 Prevalence of silent cerebral infarction in healthy (mean age 62) people at 11% in MRI study.
J26 Fructose, but not glucose, increases visceral adipose tissue and triglycerides, and lower insulin sensitivity.
J25 African Americans excrete less potassium in the urine, and it's not all due to dietary intake.
J25 Obesity drug rimonabant approved for NHS use in England and Wales.
J23 New source of cardiac stem cells found in the epicardium
J17 Big breakfast diet more effective than low-carb diet in maintaining weight loss.
J12 XBP1, stimulated by a high-carb diet, may be a new target for treatment of dyslipidemias.
J12 A subgroup of retinal cells linked to circadian cycle resetting and insomnia.
J12 FDA approves generic form of ramipril made by Lupin pharmaceuticals.
J11 Vitamin D protects heart-failure-prone rats against heart failure when fed a high-salt diet.
J10 One more argument against smoking: Increased risk of age-related hearing loss.
J10 Eating diet rich in oily fish associated with markedly reduced risk of age-related macular degeneration.
J09 115 year old woman found to have essentially normal brain on autopsy, with no evidence of Alzheimer's disease.
J06 Mechanism of action of niacin to increase HDL levels discovered.
J05 Study in mice suggests resveratrol has marked cardioprotective effects.
J05 NEJM: Aliskiren plus losartan lowers proteinuria in diabetics.
J03 Artificial blood vessel creation from smooth muscle cells makes major advances.
M28 Hope for stroke victims. Monkeys control prosthetic arm using brain waves to feed themselves.
M27 New scoring method for coronary artery calcification that takes into account extent of calcium coverage.
M27 Should HbA1c be used instead of plasma glucose to screen for diabetes?
M22 It's official: Home BP monitoring is now the standard of care.
M21 Genetic researchers identify numerous genes involved in synthesis and storage of fat in cells.
M21 After heart attack, bivalirudin better than heparin plus glycoprotein IIb/IIIa inhibitors.
M21 Modest red wine (but not beer) ingestion actually may lower risk of NAFLD - non-alcoholic fatty liver disease.
M20 Small adrenal masses found incidentally on computed tomography almost exclusively benign.
M19 Vaccine targeting amyloid beta protein prevents Alzheimer's disease in mice.
M19 American Society of Hypertension Annual Meeting (May 14-17) - abstracts at this link
M16 Small molecule found that can disassemble amyloid proteins associated with Alzheimer's disease.
M16 New NHANES analysis finds CV mortality increased in patients following a lower salt intake.
M15 Lower-dose tissue plasminogen activator treatment improves survival in patients with hemorrhagic stroke.
M15 Biopterin derivative may be effective treatment for severe heart failure.
M13 Preop beta blockers reduce heart attack risk but markedly increase total mortality.
M13 Prism eyeglasses expand view for patients with stroke-induced hemianopia.
M12 CPR rescuers do not need to stop compression while administering defibrillator shocks.
M12 Preeclampsia-like condition develops in mice with knockout of catechol-O-methyltransferase (COMT) gene
M09 Darapladib lowers the activity of inflammatory enzyme associated with vascular plaque.
M07 S100A1 protein found in heart, blood vessels; linked to heart damage and to hypertension.
M07 Women at high risk for CV events are not benefitted by homocysteine-lowering regimen of B vitamins (JAMA).
M05 ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format.
M04 Nature genetics: More obesity genes found
M02 New ACE 2 activator compounds lower blood pressure in rats and also reduce cardiac and renal fibrosis.
M01 Obesity linked to heart failure and inflammatory mediator elevation in observational study.
A30 Scientists synthesize molecule capable of releasing hydrogen sulfide over extended periods - possible role in donor organ preservation?
A29 High blood theobromine levels (presumably from eating chocolate) may protect against pre-eclampsia.
A28 Hypertension seen in the emergency department frequently misattributed to trauma, stress, and not followed up.
A25 First ever activator of ENAC sodium channel developed.
A23 High adiponectin levels linked to kidney dysfunction and albuminuria.
A22 FDA approves compact heart assist device from Thoratec.
A21 International study of chemicals in urine links blood pressure to diet and gut bacteria.
A21 Chocolate lowers LDL cholesterol by 5% in RCT.
A17 Low serum 25D levels associated with incrased peripheral arterial disease risk.
A15 Archives Int Med: Loop diuretics associated with lower bone density in men.
A15 Nurses' Health Study shows that women who follow DASH - type diet have lower risk of heart attack.
A09 NEJM: ACEI = ARB, and ACEI + ARB no better than either ACEI or ARB, in high risk patients with diabetes or vascular disease.
A09 Two enzymes associated with acetylation linked to heart muscle contraction.
A09 New Lifton study shows that some Bartter and Gitelman mutation heterozygotes are not rare, and are protected against hypertension.
A09 JAMA RCT shows American Indian tye 2 diabetics with LDL lowered to 70 have lower carotid IMT and LV mass than those with LDL lowered to 100.
A08 Slight modification to atrial fibrillation surgery improves the results.
A08 American Heart Association issues new guidelines for treatment of resistant hypertension.
A03 Daily dose of caffeine protects rabbit brains from high serum cholesterol.
A03 New Merck heart failure drug rolofylline gives encouraging results in Phase III trial.
A02 Treating hypertension in patients more than 80 years of age reduces death rate by 20%.
A02 Adenosine receptor antagonist shows promise in heart failure.
M30 NEJM: Ezetemibe lowers LDL cholesterol when added to simvastatin, but no effects on carotid artery thickness.
M27 Pretreating animals with high-dose folate lowers infarct size.
M27 NEJM: Prognostic value of coronary artery calcium content confirmed in large study.
M25 Archives study emphasizes heritability of early-onset hypertension in men.
M16 Blood vessel protein Robo4 reverses diabetic and age-related macular degeneration in mouse model.
M15 PR, QRS, and QT intervals on ECG are increased in apparently normal elderly persons over age 80.
M13 CMS: Medicare will continue to pay for CT cardiac scans for coronary artery calcification detection.
M12 New macrophage-related protein implicated in inflammatory disease.
M10 Mutated thrombin enzyme may be useful to treat heart attacks and strokes.
M07 Angiotensin vaccine moderately effective in lowering blood pressure
M06 7th Annual Prevention in Renal Disease Conference, Toronto, Sept. 19-20, 2008.
M04 Activating PPAR-delta suppresses inflammation in vascular tissues.
M04 Retinopathy may begin at lower blood glucose levels than expected.
M04 CAPON gene linked to QT interval and heart rhythm abnormalities.
F27 African American teenagers show a high prevalence of microalbuminuria.
F27 Up to 20% of persons taking aspirin show no effect on their platelet function.
F26 Heart attack rates fall in France following institution of national smoking ban in public places.
F26 FDA: Medication guide must be given to patients with each rosiglitazone (Avandia) prescription.
F23 New techniques for detecting air bubbles in blood vessels.
F21 Study suggests that Medicare part D patients use more cardioprotective drugs after MI and live longer.
F21 Salt-rich diet linked to obesity in children via sugar-containing soft drink consumption.
F20 New study confirms increased risk of kidney failure and mortality with aprotinin.
F15 Level of airborne particulates affects microvascular function.
F13 India in the middle of a catastrophic smoking epidemic
F13 University of Groningen study (PREVEND) emphasizes utility of treating hypertension in proteinuric patients.
F13 Genomic studies suggest that CETP (cholesteryl ester transferase protein) mutants protected against coronary effects of cigarette smoking.
F12 New blood test claims to identify pre-eclampsia reliably.
F12 Nocturnal noises raise blood pressure in sleeping subjects.
F11 Declining coronary artery disease rates made a U-turn in 2000, and now are rising.
F11 Reversible, but substantial, memory problems in a subset of women taking Lipitor.
F11 Very high Ang II levels found in chorionic villi of women with pre-eclampsia.
F09 Paradigm shift: Non-osmotic, inflammation-generating accumulation of sodium in the skin
F09 Death of waitress after acute asthmatic attack on entering workplace full of cigarette smoke.
F09 Calcium channel blocker treatment for HTN associated with 23% lower risk of Parkinson's disease.
F06 More on the halted NHLBI diabetes trial arm. Role of rosiglitazone use in the intensive treatment arm unclear.
F06 Beetroot juice found to lower blood pressure because of its high nitrate content.
F05 Richard Lifton, pioneer in the genetics of hypertension, receives Wiley Prize
F01 FDA warns about depressed mood, suicidal ideation in patients taking smoking cessation drug Chantix (varenicline)
J31 Sweetened soft drinks and fruit juices linked to increased risk of gout in men.
J29 Intravascular thrombolytic therapy effective against deep vein thrombosis.
J29 Diuretics produce better outcomes than other anti-hypertensive drugs in treating metabolic syndrome.
J25 Cox-2 inhibitors can cause arrhythmias by affecting potassium channels in the heart.
J22 Aspirin resistance increases risk of heart attack or stroke.
J16 Calcium supplements raise risk of heart attacks and stroke in elderly women.
J13 Pumping rat heart created by seeding a scaffolding with baby rat myocytes.
J09 Higher cholesterol levels linked to improved muscle mass with exercise in the elderly.
J09 Cannabinoid receptor blocking drug effective in causing weight loss.
J08 Risk of cardiovascular events markedly increased when 25-D levels below 15 ng/mL.
J07 Oxygen meter molecule, PHD1 knockouts survive hypoxia - potential application to early transplant viability, heart disease
D27 Aspirin increases liver enzymes in patients taking flutamide for prostate cancer.
D26 Triglycerids and non-HDL cholesterol linked to risk of stroke.
D25 Higher levels of HDL in diabetes may inhibit NO via myristic acid binding - outcome effects unknown.
D17 Drug that stimulates thyroid hormone beta receptors effective in lowering LDL cholesterol
D14 January JASN paper reports that PROActive (pioglitazone) associated with lower CV mortality in diabetics.
D12 More heart risks identified for Avandia.
D11 Physicians unaware of guidelines to treat patients with CV risk factors and metabolic syndrome.
D04 Different anticoagulant regimens after percutaneous coronary intervention yield identical results.
D04 Waistline growth on high-carb diets linked to liver gene.
D04 Renin-angiotensin linked to obesity and insulin-resistance in a gene knockout animal model.
N27 Glucose-insulin-potassium infusion after ST-elevated MI increases risk of heart failure.
N26 MRI documents second-hand smoke injury to the lungs.
N26 Nitrosyl cobamide shows promise as an NO-donor type of drug for hypertension or heart disease.
N12 Interleukin-1 receptor blocker rilonacept effective in treating chronic gouty arthritis.
N09 Simplified anti-hypertensive drug protocol seems to be more effective than more complex approach.
N08 MMWR: CDC reviews smoking prevalence in the U.S., and the results are not good.
N08 Skeletal muscle damage due to statins may operate through atrogin-1 and thus may be preventable.
N08 New nonsteroidal natriuretic hormone identified in human urine.
N07 Perioperative beta-blocker therapy shows mixed results in large RCT.
N07 Simvastatin, but not pravastatin, associated with sleep disturbances.
N07 Prazosin appears to block some glucocorticoid effects.
N07 AHA 2007 Scientific Sessions newsletter - Nov 7th.
N06 AHA 2007 Scientific Sessions Newsletter - Nov 6th.
N06 AHA 2007 Scientific Sessions Newsletter - Nov 5th.
N06 AHA 2007 Scientific Sessions Newsletter - Nov 4th.
N05 Large VA study identifies seasonal difference in blood pressure.
N03 Metabolites of flavonoid (quercetin) present in onions found to be anti-inflammatory.
N02 U.S. AHRQ releases report claiming equal efficacy for ACE-I vs. ARB in controlling blood pressure.
N02 WNK kinases identified as key regulators of blood pressure.
O25 Bayer issues additional guidance to physicians about Trasylol (aprotinin).
O25 Genzyme launches cholesterol-binding drug (Cholestagel) in Europe for patients with primary hypercholesterolemia.
O25 Uvulopalatopharyngoplasty may help some patients with obstructive sleep apnea.
O23 Global extent of obesity epidemic in the news.
O22 Chewing gum shown to help curb appetite and reduce cravings.
O19 Sudden hearing loss associated with erectile dysfunction drugs.
O12 Is fructose really that bad?
O12 Statins help preserve lung function during aging.
O08 FDA to warn of ultrasound cardiac imaging drug risks
O03 Mini-strokes (MRI study) linked to higher uric acid levels.
S25 New, synthetic version of heparin is patented.
S21 Study links TGF-beta and cholesterol to progression of atherosclerosis.
S20 Thiazide diuretics exacerbate fructose-induced metabolic syndrome.
S20 Post-reperfusion heart damage largely prevented by hydrogen sulfide.
S12 JAMA paper shows no benefit of lowering homocysteine in CKD
S10 Protein carbamylation, reflected by homocitrulline levels, strongly associated with atherosclerosis.
S07 Low vitamin D levels during early pregnancy associated with a fivefold increase in risk of pre-eclampsia.
S06 FDA approves first generic versions of carvedilol (Coreg).
S05 New ESC-ESH hypertension treatment guidelines from ESC 2007 (webcast)
S03 European Society of Cardiology 2007 meeting: Clinical Trials Updates
A27 Obesity rates climb in most states.
A27 Patient implanted with baroreceptor stimulating devise to treat refractory hypertension.
A22 Celecoxib - may reduce stent restenosis - overall safety in heart disease still remains to be deteremined.
A22 Hypertension frequently underdiagnosed in adolescents.
A22 Lack of benefit of vitamin E on heart disease may have been due to underdosing.
A20 Mechanism of adenovirus-induced obesity clarified.
A17 FDA warning letter issued emphasizing pharmacogenomic variability in warfarin metabolism among patients.
A13 New study confirms that vitamin C, E, and beta carotene, singly or in combination, of no benefit in heart disease patients.
A10 New research shows skeleton to be an endocrine organ via osteocalcin.
A08 Annals: New study questions the increased heart attack risk with Avandia; original NEJM meta-analysis claimed to have been flawed.
A06 Trial of anti-hypertensive therapy in the very elderly, more than 80 years of age, stopped early because of positive results.
J26 Diesel fume pollution linked to arterial inflammation and atherosclerosis.
J25 Obesity spreads among friends, study concludes.
J24 Soft drinks, including diet soft drinks, linked to 50% higher risk of metabolic syndrome.
J20 Cancer risk linked to CT scan for cardiac calcification (JAMA paper) in the news.
J19 Large VA study shows 50% reduction in Alzheimer / Parkinson risk with simvastatin, but not other drugs in the same class.
J19 Weight loss pill rimonabant associated with increased suicide risk.
J13 Scleroderma Outlook Improves as Survival Increases
J12 Hydroxychloroquine (Plaquenil) may be protective against developing type 2 diabetes.
J12 Serum levels of retinol-binding programs indicate level of visceral fat.
J12 Viagra may save lives in patients with pulmonary hypertension.
J11 Modified herpes virus keeps arteries free-flowing following procedures
J09 CCJM: A different approach to resistant hypertension, emphasizing hemodynamics and the physical examination.
J05 Alteplase may have pro-inflammatory effects - mitigated by cromoglycate.
J05 High sodium in many sandwiches in the news.
J05 Dark chocolate lowers BP slightly, raises levels of nitric oxide.
J02 How stress and high-calorie intact interact to increase weight and change body fat distribution.
J29 Particulates released during renal artery angioplasty can impair kidney function.
J22 FDA clears "computerized medication box" (EMMA) for U.S. market.
J19 FDA approves ambrisentan for treatment of pulmonary artery hypertension.
J19 Hypertension vaccine against angiotensin II shows positive results.
J15 Europ Soc Hypertens releases new, updated hypertension treatment guidelines.
J13 Link between restless legs syndrome and hypertension discovered.
J11 Isradipine slows Parkinson's disease development in mice
J07 New compound similar to aMSH, causing satiety, may be effective in controlling weight in the obese.
J07 Lipid chaperone protein ap2 may be a key to type 2 diabetes and its complications.
M31 Link between mercury and vascular disease involves phospholipase D.
M25 NEJM: Full text of meta-analysis that found an increased risk of myocardial infarction with rosiglitazone.
M25 Non-caffeine components of coffee lower serum uric acid levels.
M21 FDA issues safety alert for Avandia (rosiglitazone) over possible increased heart attack risk.
M21 Statins might have a role in management of hepatitis C.
M17 MMWR publishes regional stroke incidence data for the United States (2005)
M17 Debunking the slavery hypothesis of African American hypertension
M14 Effect of polyphenols (from apples, onions, green tea) on fat catabolism.
M14 Study shows unsuspected immunomodulatory effects of glucosamine.
M07 Liver, kidney damage in people taking large amount of green tea polyphenol supplements.
M07 Centrally acting ACE inhibitors may cut dementia risk in the elderly.
M07 Inactivation of ACAT2 enzyme protects fat-eating mice from atherosclerosis.
M04 Common gene variation associated with markedly increased risk of heart attack.
M03 Nicotinamide riboside, found naturally in milk, dramatically extends lifespan in yeast via sirtuins.
M02 Study highlights gender differences in susceptibility to kidney injury.
M01 Antithrombotics (e.g., aspirin) increase hemorrhagic stroke risk in the elderly.
A30 Activating PPAR-delta may burn fat and reduce metabolic syndrome risk.
A24 AGEs and food preparation may play an important role in chronic disease.
A20 New BMJ study on adverse effects of higher salt intake in the news.
A19 Fewer heart patients need antibiotics prior to dental procedures.
A18 Animal study suggests that changing to a low-fat diet can induce stress.
A15 JAM-1 protein acts in the brain to cause hypertension.
A07 Arthritis patients with CVD who take ibuprofen plus aspirin may greatly increase their cardiac risk.
A05 Think that eating only once a day will make you lose weight? Nope.
A05 Hatfield-McCoy family feud may be linked to bad temper due to heritable pheochomocytomas.
A02 High-prevalence hemachromatosis gene linked to increased risk of stroke.
M30 NEJM: Torcetrapib markedly elevates HDL cholesterol, but shows no benefit
M27 Implanted carotid artery baroreflex stimulator lowers BP by 16-20 mm Hg.
M27 New blood thinner may work without bleeding risk
M26 Drugs work as well as stents, study finds.
M26 Tolvatptan improves signs and symptoms in patients with CHF.
M26 Nesiritide safety trial shows neutral effect on mortality in CHF patients
M26 American College of Cardiology Annual Meeting March 24-27: Monday (26) Newsletter (.pdf)
M26 American College of Cardiology Annual Meeting March 24-27: Sunday (25) Newsletter (.pdf)
M26 American College of Cardiology Annual Meeting March 24-27: Saturday (24) Newsletter (.pdf)
M21 Long-term cessation of smoking may reverse arterial stiffness.
M19 Minisub developed to explore the interior of an arterial blood vessel.
M16 Fructose linked to deranged liver metabolism in rats, involving PPARs, leptin, and metabolic syndrome.
M16 Phthalate exposure linked to metabolic syndrome
M16 Chiropractic adjustment of C1 (atlas) markedly lowers blood pressure in randomized controlled trial
M16 Increased angiotensin 1-7 levels after ACE-I treatment may inhibit lung cancer
M16 Chest compressions without mouth-to-mouth better for out-of-hospital cardiac arrest
M16 An apple a day really does keep the doctor away.
M06 FDA approves aliskiren for treatment of hypertension.
M05 Dietary copper in the news after copper supplementation helps prevent heart failure in stressed rodents.
M05 Atkins diet may be the most effective with few obvious adverse effects
F28 Nifedipine found to mobilize liver iron stores in an animal model of hemochromatosis.
F26 Garlic powerless against cholesterol.
F22 Blood pressure across countries linked to level of happiness of its inhabitants.
F21 Apolipoprotein C1 linked to obesity and type 2 diabetes in American Indians.
F19 Relationship between circadian rhythm clock and blood pressure identified.
F19 CRP liver protein induces hypertension.
F16 MMWR reports on geographic variation in prevalence of heart disease in the U.S.
F14 Neutrophil-derived peptidase enzyme found to be a key player in development of aortic aneurysms.
J30 Need a new aortic valve? No problem. We'll put one in percutaneously.
J30 One third of young people who died suddenly and inexplicably had genetic arrhythmic heart defects.
J29 Health benefits of fruits and vegetables apply to their juices as well.
J29 Major link in brain-obesity puzzle found.
J27 Stroke victims who suddenly lost the urge to smoke identify brain addiction region.
J22 Surprising beneficial effects of losartan on muscle in mouse models of muscular dystrophy or Marfan syndrome
J19 Nintendo Wii videogame use promotes weight loss (n=1).
J17 Strong association between low LDL levels and Parkinson disease identified in small study.
J17 Interesterified fats being used to substitute for trans-fats, but new study shows that they are unhealthy, also.
J16 DNA test to be used to determine warfarin dose.
J15 Pancreatic-polypeptide containing chewing gum - a new potential weapon against obesity
J15 New gene linked to Alzheimer disease
J09 Milk appears to eliminate the cardiovascular benefits of tea
J02 Higher serum uric acid levels associated with cognifitve impairment in the elderly.
J02 Twenty-five best dieting tips ever
J02 Moderate alcohol consumption in hypertensive men associated with lower risk of heart attack.
D27 Green vegetables may lower blood pressure via nitrates.
D20 Friendly microbes could make you fat: Bacteroides vs. Firmicutes
D13 Garlic: Good against vampires, but little protection against cardiovascular risk.
D12 Diet resulting in 10% body weight loss leads to measurable loss in bone density over 1-year period.
D12 Man eats pastrami and cheesecake, has heart attack, sues Atkins company, unsuccessfully.
D11 FDA proposes rules overhaul to expand access to experimental drugs.
D10 MRI scan used to quantify visceral fat.
N29 Procyanidins identified as cardiovascular protective agents in wines; French, Sardinian wines have the most.
N28 Folic acid, homocysteine, and cardiovascular disease: (Full text article in BMJ)
N28 Meta-analysis published in BMJ supports folate supplementation to reduce heart disease risk.
N27 Statin use in otherwise healthy people of dubious benefit.
N27 Richard Lifton honored by two medical societies for work on hypertension.
N27 Gene linked to wet form of macular degeneration.
N26 HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts
N16 Reanalysis of TNT study presented at AHA: Suggests high-dose atorvastatin lowers stroke, CV risk in CKD patients.
N14 Results of TROPHY prehypertension study suggesting benefit of candesartan are questioned.
N14 Fat cells stimulate the adrenal glands to secrete aldosterone: obesity - hypertension link?
N14 NEJM: No survival benefit to angioplasty done 24 hours after myocardial infarction.
N13 American Heart Association Scientific Sessions daily news: Tuesday, Nov 14
N13 American Heart Association meets in Chicago: Monday, Nov. 13 news (pdf)
N13 American Heart Association meets in Chicago: Sunday, Nov. 12 news (pdf)
N13 Pioglitazone reduces progression of atherosclerosis in diabetics
N11 Link between low systolic blood pressure and poor outcome in heart failure patients highlighted in nonuremics.
N07 Why do we eat mindlessly and what would induce us to stop?
N06 Lipoic acid may retard vascular stiffening, aging, via ceramide and phosphatases.
N06 Children's belly fat increases by more than 65% since 1990.
N02 Study shows strong link between serum uric acid levels and hypertension in African Americans
N02 Life saving pump lets heart heal
O30 UT Southwestern looking for patients with severe CHF for optimizer device study.
O25 Human tests underway on intravascular stents that dissolve.
O23 FDA approves once-a-day Coreg (carvedilol) CR for 3 cardiovascular indications
O18 Benefits of eating fish outweigh the risks
O12 Get on scale daily to keep off lost pounds.
O11 Most decaffeinated coffee contains substantial amounts of caffeine
O03 Benefits of ultralow LDL cholesterol targets (70 mg/dL) questioned.
S26 H2-blocker (famotidine) appears to have a beneficial effect in heart failure.
S18 Low blood levels previously thought to be safe linked to risk of CV death
S18 ESRD patients with implantable defibrillators at higher risk of arrhythmia.
S14 MMWR documents rising tide of obesity in the United States.
S14 Pioglitazone shows benefits in terms of cardiovascular outcomes.
S13 More bad news in JAMA paper about CV and kidney risks of COX-2 inhibitors and NSAIDS
S12 New class of pain relievers may help, not hurt, the heart
S11 Want to fight fat? Eat brown seaweed!
S07 Pre-eclampsia breakthrough hope (NEJM)
S05 Pioglitazone reduces secondary stroke risk by 50%.
S05 Carbon monoxide cytoprotective effect may explain lower risk of pre-eclampsia in smoking moms.
S05 U.S approves humanitarian use of Abiocor permanently implanted total artificial heart.
S05 Good one-year control of BP with aliskiren (Rasilez) presented at World Congress of Cardiology
A21 Red and white wine may be equally good for the heart
A18 Role of BMI as a measure of obesity and cardiovascular risk questioned.
A18 Genetic clues to cardiomyopathy and sudden death found in mice - emphasis on the right ventricle
A18 CDC: New U.S. blood lead survey data results: prevalence of elevated blood lead levels slowly improving.
A17 FDA approves use of clopidogrel for ST-segment elevating MI treated medically.
A08 Duke randomized trial favors Atkins style diet over low-fat diet.
A02 Gout increases the risk of heart attack
J31 Scripps research scientists test anti-obesity vaccine
J28 Nanotech used to concentrate angiostatin-like drugs in vascular plaques.
J25 Digitalis relatively safe treatment for diastolic heart failure.
J20 Mayo Clinic researchers discover a genetic cause of atrial fibrillation.
J15 Retinal blood vessel width may be a good indicator of coronary artery disease risk.
J29 NHLBI offers DASH diet eating guide
J28 UK NHS recommends against beta-blocker use for initial treatment of hypertension.
J22 New fat-burnng gene linked to metabolic syndrome.
J20 AHA issues new dietary recommendations; saturated and trans-fat intakes further limited
J16 CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!)
J14 Feeding monkeys a high trans-fat diet markedly adds to abdominal fat.
J08 Benefits of potassium-enriched salt on CV mortality in elderly men
J07 Congenital malformations with first-trimester ACE-inhibitor therapy.
J05 Isis Pharma gets orphan drug status for familial hypercholesterolemia drug.
J05 International trial to see whether or not niacin can prevent heart attacks and strokes
J02 Heart attack risk with COX-2 broadened to include most NSAIDs
M30 It's the magnesium, stupid!
M24 Gum-disease bacterium can infect human arterial cells - is this the hypothesized periodontitis - CVD link?
M22 Study suggest that thiazides may have an adverse effect on CRP.
M22 Trandolapril / verapamil lowers risk of diabetes in Hispanic patients
M22 Ethanol- and smoking-induced upper digestive tract cancers linked to acetaldehyde; preventable via oral l-cysteine
M18 QTc interval and magnesium deficiency: Treatment with Mg Lactate
M17 Chocolate good? Coffee is too! Enjoy.
M15 75% of Irish taxi drivers have hypertension
M15 Moderately increased BMI in the elderly associated with reduced mortality
M15 Tacrolimus-derivative drugs protect animal brains against stroke-induced damage.
M13 Up to 40% of hypertensives in China have diabetes.
M13 FDA approves novel medication (varenicline) for smoking cessation
M11 Common (15%) gene variant affecting fatty acid breakdown increases CAD risk by 50%.
M05 Coffee consumption not associated with heart disease risk.
M03 Diuretics more effective in preventing heart failure in hypertensives when used as first-line drug.
M03 Mayo: 20 g sodium, 50% saturated fat diet improves BP, lipids in obese.
M01 Obesity rates in the U.S. underestimated by 50% due to inaccurate patient self-reporting.
M01 Common nerve cell gene plymorphism linked to QT interval changes, sudden death.
A28 Magnesium deficiency and metabolic syndrome re-emphasized
A28 Does chamomile tea interact with warfarin?
A26 FDA approves first generic pravastatin.
A25 Fatty acid binding protein aP2 gene variant associated with atherosclerosis, type 2 diabetes, in humans.
A25 Anti-oxidant selenium offers no heart disease protection in first large randomized controlled trial.
A19 An integrin-family platelet receptor found to be defective in thrombasthenia, with general implications for blood clotting.
A13 CNTF can overcome leptin resistance to fight obesity.
A08 AMBI (Tarrytown company) gets exclusive rights to Finland's PANSALT distribution in the U.S.
A08 Losartan can prevent progression of Marfan syndrome (in mice) via inhibition of TGF-beta
A04 Epicardial fat and adipocytes around coronary arteries may contribute to CAD.
A04 Lack of sleep linked to hypertension risk
M30 Manipulation of intracardiac catheters by externally applied magnetic fields to cure a. fib.
M30 Apparent CV protective effect of alcohol intake may be due to a statistical fluke.
M24 Study focuses on bread as a major cause of higher salt intake.
M24 Benefits of eating oily fish seem to be slip-sliding away.
M17 Virus blamed for obesity epidemic.
M16 Glycemic index is bupkus.
M15 Specially formulated salt substitute cuts hypertension.
M14 ACC Scientific Meeting, Atlanta: Tuesday, March 14th Newsletter (.pdf)
M14 ACC: Early treatment of pre-hypertension may postpone onset of true hypertension
M13 Diuretics, and especially, K-sparing diuretics, markedly lower risk of Alzheimer's disease.
M13 American College Cardiology Meeting: Monday, March 13th newsletter (.pdf)
M13 High dose statin therapy causes regression of coronary atherosclerosis.
M13 High-dose atorvastatin (Lipitor) improves kidney function in CKD patients in large clinical trial.
M13 Another take on B vitamins, homocysteine, and vascular risk.
M13 NEJM: B vitamins for homocysteine lowering: Fewer strokes, but more unstable angina.
M13 NEJM: Homocysteine lowering by B-vitamins of no benefit post MI - trend toward increased risk.
M13 American College of Cardiology (Atlanta) Sessions: Sunday highlights. (.pdf)
M13 American College of Cardiology (Atlanta) Sessions: Saturday highlights. (.pdf)
M13 NEJM study casts doubt on efficacy of Plavix over aspirin - and higher bleeding risk cited.
M10 Blood pressure is falling globally, and no one knows why!
M10 Major WHO study concludes calcium supplements can reduce severity but not incidence jtd of preeclampsia.
M08 Diabetes drug Byetta (exenatide) gaining attention as weight loss aid.
M07 Heavy coffee drinking plus gene variant tied to heart attack risk in Costa Ricans
M03 Serotonin may play a role in hardening of the arteries.
F28 Stress may trigger heart attacks by increasing number of blood platelets.
F22 Genetic tests developed to test for salt-sensitivity of blood pressure.
F20 Mars chocolate maker to introduce foods with flavonol-rich chocolates.
F17 Fat in liver connected to high blood pressure risk.
F12 WHO report identifies relatively high hypertension rates in males from India.
F10 IU scientists using stem cells to treat severe peripheral arterial disease.
F10 Blood levels of aldosterone linked to preservation of hearing with aging.
F07 Low fat diet benefits for women less than expected.
F05 Basic gender difference identified in coronary artery disease.
J31 AHA Scientific Statement: Dietary approaches to treat hypertension
J30 Certain adenovirus infections linked to obesity on animals and humans
J28 FDA approves first ever inhaled insulin for the treatment of diabetes.
J26 Aprotinin (Trasylol) linked to increased risk of kidney failure, heart attack and stroke.
J24 Alagebrium (a collagen cross-link breaker) softens arteries - and that's good for you.
J24 Study of Kuna indians is good news for chocoholics - procyanidin in cocoa lowers BP.
J23 Fermented milk drink reduces high blood pressure.
J23 Fetal form of toponin I, with a histidine for alanine substitution, has cardioprotective effects.
J22 AHA review casts doubt on cardiovascular health benefits of soy-based foods.
J21 British study shows that work stress linked to both heart disease and metabolic syndrome.
J19 Heart-healthy compound in chocolate identified - it's epicatechin.
J17 Aspirin protects men against myocardial infarcts and women against ischemic strokes.
J17 US FDA considering two new drugs that fight obesity.
J17 Activated blood coagulation factor VIIa under study to treat intracerebral hemorrhagic stroke.
J16 Tomato extract seems to have a large effect on lowering blood pressure.
J16 Annals: More exercise associated with 30-40% reduction in risk of dementia.
J15 Acetazolamide reduces sleep apnea severity in heart failure patients.
J15 Hypothalamus has a fatty acid sensor that may regulate food intake
J12 Caloric restriction appears to make the heart more elastic.
J10 Mid-life obesity increases mortality and cardiovascular risk.
J09 Smoker? Drink tomato juice (or drink bloody Marys) to ward off emphysema.
J04 Adenosine receptor antagonist completes phase 2 trials for congestive heart failure.
J02 UCSF study in Annals suggests that obesity increases risk of kidney failure.
J02 U.S. weighs obesity surgery options
D28 Researchers discover molecular link explaining why high-fat diet can cause type 2 diabetes.
D27 Do low birth weight babies like saltier food? Study on birth weight stirs up salt wars.
D26 Diabetes, CHF home patient monitors taking off in the UK.
D23 JAMA: Air pollution and high-fat diet combine to cause atherosclerosis in mice.
D20 Allergic reactions from drug-eluting stents
D15 Both BNP and NT-proBNP useful to deteck CHF in persons with CKD.
D07 Fructose may be cause of obesity epidemic; also raises uric acid.
D05 Heparin antibodies pose risk in heart surgery patients.
D03 Random testing shows high lead levels in some imported Chinese plums.
D03 CV benefits of lower intakes of alcohol called into question.
N29 Why trying to make couch potatoes exercise may be difficult.
N29 New AHA CPR guidelines: 30:2 compressions, cooling to 90 degrees.
N29 Fatty liver being seen increasingly in obese patients.
N28 High-carb diet linked to diabetic hypertension.
N28 Nabi's nicotine vaccine shows promise in helping smokers quit.
N24 Osteoporosis associated with six-fold increase in risk of heart disease.
N23 Sweat is a good indicator that a heart attack may be coming.
N22 Percutaneous laser myocardial revascularization no better than placebo.
N22 AHA: Late-breaking clinical trial abstracts (.pdf)
N21 Roller coaster rides can provoke arrhythmias.
N19 Researchers zero in on possible viral cause of Kawasaki disease.
N17 AHA: CV mortality benefits of diuretics linked to alpha-adducin genotype.
N16 Low-carb diet better than low-fat for improving metabolic syndrome.
N16 Collagen crosslink breaker alagebrium can soften arteries.
N16 AHA: Autologous stem cell infusions show promise in severe CAD.
N16 AHA: Aliskiren (renin inhibitor) adds to anti-HTN effects of irbesartan.
N16 Drinking decaffeinated coffee increases pro-atherosclerotic ApoB levels.
N16 Trichostatin may reduce premature atherosclerosis in lupus patients.
N16 High HDL level is pro-atherosclerotic in lupus patients.
N16 Pioglitazone reduces heart attack rate in type 2 diabetics by 28%.
N16 AHA meeting in Dallas: Wednesday newsletter.
N15 GRK5 involved in arterial restenosis lesions.
N15 AHA Meeting in Dallas: Tuesday daily newsletter (.pdf)
N15 AHA Meeting in Dallas: Monday daily newsletter (.pdf)
N13 AHA Scientific Sessions open in Dallas: Sunday daily newspaper.
N12 Risk-stratified analysis proposed to analyze RCTs to detect harm.
N12 Statins overcome learning disabilities in mice with neurofibromatosis 1.
N10 Fizzy cola consumption associated with HTN in women.
N09 No link between coffee drinking and hypertension in women.
N06 New FDA-supported website lists latest approved drug labels for all meds.
N05 Waist-hip ratio better than BMI to predict CV risk.
N01 Diabetic blacks have less coronary artery disease than diabetic whites.
O28 Botox injections effective in treating stroke spasticity.
O28 Air pollution linked to ischemic stroke risk.
O28 HDL cholesterol involved in immunity against parasites.
O27 Bone marrow stem cells may help heal hearts years after heart attack.
O27 JASN Express: Pravastatin lowers CV death risk in diabetics with CKD.
O26 ASN Renal Week 2005 abstracts now available on-line.
O25 Got high BP? Just zap your PAG - but make sure it's the front part!
O23 JAMA: Increased mortality after bariatric surgery.
O23 JAMA: Article detailing CV risk increase with Pargluva (muraglitazar)
O19 Lancet study questions efficacy of beta-blockers for hypertension.
O18 Role of prolonged bedrest to manage hypertension in pregnancy questioned.
O18 Researchers closing in on Na-K-ATPase inhibitor hormone; role in preeclampsia?
O17 Dopamine receptor gene found to play a role in blood pressure inheritance.
O16 JAMA: Cholesterol levels in U.S. inhabitants continue to drop.
O11 Fatty foods can fight inflammation, induce satiety, via CCK.
O11 Surgical menopause can trigger salt-sensitive hypertension.
O11 Microsvascular changes in the retina linked to strokes, even with normal BP.
O11 Study questions measurement of C-reactive protein to assess cardiovascular risk.
O10 RBC secretion of s-nitrosothiol regulates vascular (esp. pulmonary) tone.
O09 JASN: Glycosylated Hb in non-diabetic CKD pts. increases mortality risk.
O09 Hypertension prevalence 25% or higher in middle-aged Beijing residents.
O09 SEPS 1 gene on chromosome 15 plays key role in inflammation.
O07 Lancet: Pioglitazone lowers risk of heart attacks and strokes in diabetics.
O06 Soy compound, genistein, found to inhibit amyloid plaque formation.
O05 Generic form of amlodipine approved by the FDA
O04 Addition of amiloride to HTN drug regimens helps, esp. in African Americans.
O04 90% of Framingham cohort over 60 years of age now overweight.
S28 Toprol (metoprolol)/Topamax/Tegretrol look-alike names prompt FDA alert letter.
S28 beta-2-adrenergic receptor genetics determines survival after MI.
S26 AHA issues dietary recs for children and adolescents.
S26 Lancet study suggests wider use of statins in higher dosages may be beneficial.
S26 Smoking appears to double the risk of developing type 2 diabetes.
S26 Lead exposure plus high blood pressure may impair mental ability.
S25 Genes on chromosome 2 linked to resistant hypertension.
S23 Panic disorder may increase risk of coronary artery disease.
S22 NEJM: Efficacy of various strategies to raise HDL cholesterol.
S22 Surprisingly high cancer, heart death rates in 1-4 cig/day smokers.
S20 Novartis oral renin inhibitor aliskiren shows good results in phase III trial.
S17 Fat cells linked to production of CRP via resistin.
S13 Pioglitzaone improves cardiovascular outcomes in diabetics.
S13 Low-dose aspirin might protect against cardiac effects of COX-2 inhibitbors.
S09 MMWR: Cholesterol screening rates increasing, but only modestly.
S06 Eur Soc Cardiol 2005 Congress website
S06 CV outcomes better with amlodipine / perindopril than with atenolol / diuretic.
S06 Calcium scans can predict heart disease in healthy men.
S06 ESC 2005: Fondaparinux safer than enoxaparin, and as effective
S06 Soy protein-rich diet may help prevent fatty liver of diabetes.
S06 Folic acid, B vitamins lower homocysteine, but show no heart protective effects.
S01 JCI: New kidney hormone identified that metabolizes catecholamines.
A29 Coffee is number one source of antioxidants in U.S. diet.
A29 Prompt statin therapy after heart attack cuts mortality risk in half.
A26 Metabolic syndrome doesn't exist, diabetes groups claim.
A24 TFAH releases report on obesity in America - we're all getting fatter.
A24 The American Society of Hypertension ditches AmJH for JCH.
A22 Scios announces recommended use initiative for Natrecor.
A19 Research promising for chocolate lovers.
A19 Jury awards widow 253 million in Vioxx suit against Merck.
A19 Myogen announces phase 2 trial results of darusentan in resistant hypertension.
A17 Bluetooth scanner stroke hope.
A16 Analgesic drug use linked to high blood pressure in women.
A16 After overeating we don't compensate by eating less.
A16 PLEKHA1 gene linked to age-related macular degeneration.
A13 NEJM: Retinoid X receptors - new targets to treat metabolic syndrome.
A11 Following clinical guidelines in elderly can lead to polypharmacy.
A09 Modified form of digitalis finds role as a cancer killing drug.
A09 Salt restriction lower BP and urine protein in Blacks.
A04 Prehypertension triples heart attack risk.
J28 JASN: ADMA strongly predictive of CKD progression
J28 Propanolol may be useful in erasing traumatic memories in PTSD patients.
J25 Cocoa flavonoids: Eat two chocolate bars and call me in the morning.
J25 How estrogen via its alpha receptor may be bad for women's hearts.
J23 TGF beta receptor mutations linked to aortic dissections.
J22 NEJM: Statins had no effect on hard outcomes in diabetic ESRD patients.
J20 JASN early release: Short daily HD lowers LVH by 30%, also CRP.
J19 Annals: If Medicare were to provide ACE-I for free, it would be cost effective.
J19 Natrecor (nesiritide) safety summary (Scios)
J19 ALLHAT suggests that diuretics rule, even in Blacks with metabolic syndrome.
J19 Dark chocolate and blood pressure in the news (watch the oxalate!).
J17 Mutations in NOTCH1 gene linked to aortic valvular disease.
J17 Faulty ENPP1 gene linked to diabetes and obesity.
J15 Ruboxistaurin reduces vision loss in diabetics with macular edema.
J14 NEJM op-ed piece attacks continued use of nesiritide.
J11 Walking on cobblestones reduces blood pressure, improves balance.
J11 Hageman clotting factor linked to atherosclerosis.
J06 Therapeutic robotics offers new benefits for stroke patients.
J06 Expanding definitions of disease: economic consequences
J06 Vitamin E supps do not protect women from heart attack, stroke, or cancer
J04 Implanted stomach stimulator used as an alternative to stomach-stapling surgery.
J30 Gastric bypass surgery lowers CRP by 50%.
J30 CRP receptor in endothelial cells identified.
J30 ALLHAT subanalysis shows diuretics lower CV risk in diabetics as well as ACEI
J29 Consumer reports announces "best buy" calciuim channel blockers.
J29 Singing exercises for throat muscles target snoring, sleep apnea.
J28 Pfizer review claims no link between Viagra use and blindness.
J26 Gene hunters flock to Amish country.
J24 FDA refuses to approve broader use of Abiomed artificial heart.
J24 US FDA approves BiDil for African Americans with CHF.
J23 AHA: Public access defibrillator study doubles survivals: Policy statements.
J22 Initial FDA review of Abiomed artificial heart is mixed.
J17 FDA advisory panel recommends approval of BiDil for CHF in Blacks.
J17 High levels of ADMA associated with renal disease progression in CKD.
J17 John Laragh raises concern about MD conflicts of interest at the Am Soc HTN.
J17 Study sheds light on why diabetes drugs (thiazolidinediones) cause edema.
J16 BMJ: Should everyone over 50 be taking a daily aspirin?
J14 FDA examines application of BiDil (two vasodilators) to treat CHF in Blacks.
J14 Viagra effective in treating pulmonary arterial HTN in kids.
J13 Highlights from Am Soc Hypertens Meeting (via the ESH)
J13 Compression stockings markedly cut risk of DVT on airplane flights.
J07 Plasma BNP distinguishes restrictive myopathy from constrictive pericarditis
J07 Low vitamin B12 levels common, associated with high homocysteine levels.
J05 Gene therapy reverses pulmonary hypertension
J04 JASN Express: Crit-line blood volume monitoring fails to reduce hospitalizations
J04 CDC defends its position about obesity and increased mortality risk.
M31 Off-pump, on-pump cardiac bypass methods give comparable results.
M27 Adverse impact of second-hand smoke stronger than previously believed.
M25 Atherosclerosis linked to inefficient mitochondria in vascular endothelial cells
M24 Crestor (rosuvastatin) associated with higher adverse event risk.
M24 Higher milk intake associated with lower CV, stroke risk.
M21 Am Soc Hypertension writing group comes up with new definition of hypertension.
M20 American Society of HTN 2005 meeting abstracts
M19 Am J Nephrol: Carnitine therapy associated with decreased hospitalizations
M18 NEJM: Cystatin levels predict mortality better than Scr in the elderly..
M18 Arteriosclerosis Thrombosis Vasc Biology abstracts, 2005 (pdf)
M18 ASH: New onset diabetes 23% higher with amlodipine vs. valsartan.
M12 Animal studies suggest thyroid hormone may help failing hearts.
M12 Active vaccine prevents prion disease from developing in mice.
M10 Am Soc Hypertension focuses on Hispanic hypertension.
M10 Threefold increase in sudden cardiac death from certain non-cardiac drugs.
M09 Pioglitazone reduces carotid artery thickness in diabetics.
M07 Immune gene with 20% prevalence linked to CAD, rheumatism, and MS.
M06 Madison and Montreal researchers study genetics of HTN in French Canadians.
M06 Pegaptanib shows promising results in treating diabetic macular edema.
M05 Overexpressing catalase in mice mitochondria extends lifespan by 20%.
M03 Consumer Reports website suggest Best Buys for ACE inhibitors.
M03 Schelling paper that is the basis for the dipstick protein-SC calculator
M03 Schelling-Case Western dipstick proteinuria/specific gravity calculator.
M02 Is it raining nanobacteria and if so, is this an important health problem?
M02 FGF-21 finds itself as a new therapy for type 2 diabetes.
M02 Transcendental meditation may expand lifespan in 18 year randomized trial.
A29 ACAT2 cholesterol transforming enzyme a key player in atherosclerosis.
A28 Potassium channel gene linked to how much sleep different persons need.
A27 Combo Vytorin (ezetimibe + simvastatin) lower CHO better than atorvastatin alone
A21 Could an adenovirus be responsible for recent epidemic of obesity?
A21 My.pyramid.gov - new U.S. government website with dietary guidelines
A21 Studies in mice tie sleep disturbances to metabolic syndrome.
A20 Obesity death risk overstated; modestly obese have higher survival rate.
A20 Nesiritide associated with an increased death rate in CHF patients.
A18 Melbourne researchers develop safer and more effective "aspirin".
A17 Exercise has trivial effect, and only on DBP, in older adults.
A14 Heart ring fixes two problems at once.
A13 Heart valve ring reverses damage from congestive heart failure, easing symptoms
A11 New gene found in 20% of people may be behind CV-inflammatory syndrome.
A08 New kidney protein 'renalase' - regulates heart contraction and blood pressure
A08 Liver may be source of 'good' cholesterol
A07 Excimer laser angioplasty used to reduce renal artery stent restenosis.
A06 Table of contents for new K/DOQI cardiovascular guidelines
A06 NKF guidelines relating to cardiovascular disease published.
A06 JAMA: ALLHAT results suggest diuretics best for both Whites and Blacks with HTN.
A06 Kidney transplant can markedly improve patients with severe heart failure.
A04 Viagra benefits hypertensive pregnant mother and fetus in animal study
A04 Cholesterol lowering drugs may lower IC calcium and inhibit proliferation.
A03 Garlic ingredient allicin protects against pulmonary HTN in rats.
A03 Cranberry juice improves blood vessel relaxation.
A02 Subintimal angioplasty offers new hope for peripheral vascular disease pts.
A01 Best buy recommends best value beta-blockers.
A01 Implanted medical device aims to lower blood pressure.
M31 NEJM: Higher dose aspirin better than warfarin in secondary stroke prevention.
M29 Uric acid not a good predictor of coronary disease in meta-analysis.
M29 Production of inflammatory mediators by fat cells linked to metabolic syndrome.
M29 Study in rats shows that acupuncture can markedly lower blood pressure.
M21 Nesiritide associated with risk of reduced kidney function in CHF patients.
M14 Finland gene mapping project identifies 300 new hypertension genes.
M11 Impedance cardiac output utility to guide HTN treatment featured.
M11 CCB/ACEI better than BB/diuretic for HTN in terms of hard outcomes.
M10 Clopidogrel after acute MI shown to increase survival.
M07 Urine mediators help diagnose pre-eclampsia.
M07 Laughter may cause endothelium-mediated vasodilatation.
M07 TIA symptoms may portend impending stroke.
M07 Low-dose aspirin shows only mild benefit in preventing strokes in women.
M07 Hyponatremia a marker of poor outcome in heart failure
M05 Pfizer working on new drug that raises HDL cholesterol.
M02 FDA posts warning: Reduce starting dose of Crestor in Asians.
F24 Consumer group sues FDA demanding that salt in foods be regulated.
F22 Probably trigger of diabetic kidney disease uncovered (CD36)
F15 MMWR: Blacks and Hispanics less aware of high cholesterol problems.
F15 COX-2 inhibitors associated with blood pressure elevation.
F14 Hypertension awareness among Hispanics found to be critically low.
F11 Bad news can really break hearts
F09 Hypertension in African Americans linked to two genomic regions
F06 Stopping aspirin therapy associated with markedly increased stroke risk.
F03 Air pollution exposure linked to atherosclerosis.
F03 Fidgeting important to help avoid obesity.
F03 Microdosing used to study pharmacokinetics of new renin inhibitors.
F02 Blood pressure soars on Mondays.
F01 Statin use associated with 30% lower mortality in dialysis patients.
F01 More heart attacks occur on Mondays in non-dialysis patients.
J25 In retrospect, Vioxx may have caused many heart disease deaths.
J20 NEJM: Aspirin/esomeprazole better than clopidogrel for CV risk prevention.
J20 New SARS-like coronavirus linked to Takayasu's disease.
J18 New research shows that all COX-2 inhibitors may have CV health risks.
J18 U.S. launches diabetes campaign aimed at seniors.
J18 Large doses of folate may stave off high blood pressure.
J18 California researchers discover new fat gene.
J17 FDA requires handout be given to patients receiving amiodarone.
J16 Pediatricians now recommend that BP screening start at age 3.
J15 FDA panel rejects OTC sale of statin drug made by Merck
J15 MMWR: Latest prevalence data for HTN by race in the United States.
J14 One third of world population expected to have HTN by 2025.
J13 Study shows how angiotensin II can lead to muscle wasting and CHF.
J11 Insufficient sleep linked to obesity.
J11 Death in patient taking Crestor who had rhabdomyolysis.
J10 New generation of video games/muscle trainers may fight obesity.
J06 NEJM: LDL cholesterol and CRP each strong, independent, predictors of CV risk.
J05 BMC: Middle-aged Germans, not Blacks, have highest incidence of HTN (.pdf)
J05 JAMA: RCT of various weight loss diets shows that no one diet is clearly better.
J05 JAMA: Low urinary placental growth factor in women with pre-eclampsia.
J04 Benefits of diuretics in the elderly outweigh the risks.
D31 Fast food intake linked to obesity, insulin resistance.
D30 Heart failure patients treated with insulin have increased mortality
D28 India spice curcurmin more effective against Alzheimer's than any meds.
D28 JAMA: Editorial on arthritis medicines and CV risk
D28 AHA: Top 10 advances against CV disease for 2004.
D28 Chocolate: A boon for libido and for the heart.
D28 NIH, JDRF, CDC announce new genetic data bank for diabetic kidney disease.
D22 Aspirin underused by people with diabetes.
D22 Exercise before a fatty meal may curb bad effects on vasculature, triglycerides.
D22 FDA statement regarding CV risks related to naproxen.
D22 New AHA guidelines emphasize home monitoring of BP.
D22 LDL vaccination reduces amount of coronary artery plaque.
D21 Naproxen linked to increased risk of heart attack, stroke.
D17 Polymeals containing super-healthy nutrients, might extend life.
D16 NEJM: Infection (bronchitis, cystitis) increases heart attack risk fivefold.
D14 Thiamine supplementation lowers CV risk in diabetics.
D14 Anti-HTN drug combo that included a CCB showed higher death risk in women.
D14 MIT scientists get working heart tissue from cultured myocytes.
D13 European salt producers fight back against low-salt trend with website.
D08 Amlodipine/perindopril vs. HDCN/atenolol (ASCOT) trial halted early
D07 Penn study shows differences in mortality between Vioxx and Celebrex
D07 Lack of sleep may make you fat via ghrelin and leptin.
D05 Vascular effects of selective COX-2 inhibitors (.pdf)
D05 Risk of obesity-related deaths in the U.S may have been overstated.
D02 Milk protein may reduce high blood pressure.
D02 High body fat may impair natriuresis in African Americans.
D02 Exercise training does not work for everyone.
D01 Gene transfer shows AT type 2 receptors protect against LVH.
D01 Drinking tap water could be beneficial to patients with low blood pressure.
N29 Panama's heart-healthy Kuna Indians suggest that chocolate may be a health food
N26 More muscle means better regulation of blood pressure
N26 New findings link IL-10 to atherosclerosis, identify intermediary molecule.
N18 Don't like wine? Try Concord grape juice to lower inflammatory markers.
N18 NEJM: Ultrasound plus tPA helps dissolve stroke-causing clots
N18 Cox-2 inhibitors may work against estrogen and promote hardening of arteries
N14 Was Atkins right all along? Higher fat diets lower CV risk in elderly women.
N13 Exercise may protect the heart by stimulating VEGF
N11 N EJM: No CV benefit of ACE-I in patients with stable CAD
N11 NEJM: Isosorbide dinitrate and hydralazine in heart failure works in Blacks
N11 Acetaminophen-pretreated dogs show astounding reductions in heart infarct size
N10 Pfizer COX-2 inhibitor also doubles risk of heart complications
N09 Hydralazine plus isosorbide dinitrate markedly benefit Blacks with heart failure
N09 Walnut and flaxseed oil lowers inflammatory markers
N09 Progress with tissue-engineered blood vessels for coronary bypass
N09 ACE inhibitors of little benefit for patients with stable heart failure
N09 DHEA may reduce abdominal fat in the elderly and improve insulin sensitivity
N07 Elastic wrap for the heart give 75% improvement in severe heart failure
N07 AHA: Heart disease slidesets
N07 Genetic testing can identify ischemic vs. nonischemic heart failure
N07 Air pollution may cause and speed up heart disease
N05 Outcome benefits of atenolol questioned
O31 ASN: Coronary angiography or bypass underutilized in dialysis patients
O30 The amyloidogenic role of apolipoprotein E in Alzheimer disease clarified
O29 New theory links low NAD/NADH ratio to diabetic organ damage
O28 Salt retention gene CYP3A5 polymorphisms vary with distance from equator
O26 KDIGO.org website now up for international kidney disease guidelines
O26 Immunization retards plaque growth in animal model of Alzheimer's disease
O26 Transthyrethrin protects mouse brains against experimental Alzheimer's disease
O24 AHA African American media kit (patient guidesheets) (.pdf)
O24 FDA approves Syncardia temporary artificial heart
O21 Mitochondrial mutation linked to high blood pressure
O19 Minimally invasive surgery highly successful in reversing atrial fibrillation
O19 CD36 gene polymorphisms tied to heart disease in diabetics
O18 European Soc Cardiol guidelines for prevention of CV disease
O18 Kaiser Permanente adult diabetes management guidelines
O18 KDOQI Clinical Practice Guidelines for treating hypertension in CKD
O16 Ephedrine linked to sudden death in a coronary compromised dog model
O16 MMWR: Focus on health disparities, diabetes in Hispanics (.pdf)
O15 Eur Soc Hypertension guidelines for treating arterial hypertension
O13 Statins reduce brain amyloid plaques in an Alzheimer's disease animal model
O11 High folate intake associated with lower blood pressure in women
O11 Insulin resistance in teens raises BP risk as adults
O11 Obesity in children, adolescents is focus of new IOM report
O06 JAMA: Hormone replacement therapy doubles blood clot risk
O06 Many benefits of exercise may be mediated by interleukin-6
O05 Pyridostigmine effective in combatting orthostatic hypotension
O04 External counterpulsation trousers used to treat refractory angina
O03 Serum CRP and other inflammatory markers higher in coffee drinkers
S30 Carp heart doesn't need oxygen; fish converts its lactic acid to ethanol
S24 NCQA reports that half of patients get bad care, esp. HTN management is poor
S24 Even mild kidney disease raises risk of heart disease and death
S15 Beta-blocker use associated with lower risk of bone fractures
S13 Clonidine may act partly via imidazoline receptors in the brain
S12 Chronic hyperphosphatemia elevates fibroblast growth factor levels
S08 In women, fitness level, better than obesity, predicts cardiovascular risk
S06 Heart disease incidence related to gene mutation controlling vascular EC matrix
S01 Farm-raised salmon fed vegetable oil don't cardioprotect
A30 High incidence (7%) of subclavian stenosis can confound BP measurement
A24 Prevalence of high blood pressure in US markedly increased
A23 Activation of leukotriene pathway increases aortic aneurysm formation in mice
A18 Snake venom reveals undesirable partial agonism of integrin receptor blockers
A14 Mutant gene discovered that affects dietary cholesterol absorption
A09 Doctors warned on single high blood pressure reading
J31 Angiotensin (1-7) peptide appears to inhibit growth of lung cancer
J30 Financial breaks speed adoption of cardiovascular health guidelines
J29 Trial testing isosorbide dinitrate + hydralazine in Blacks with CHF halted
J26 Drinking tea associated with lower blood pressure
J21 Eating oily fish reduced risk of atrial fibrillation by 1/3
J16 Medicare to cover some obesity treatments
J13 Governments drafting laws, policies, to tackle obesity
J12 Updated NCEP Panel III Cholesterol Treatment Guidelines
J12 NCEP updated cholesterol guidelines for adults; lower levels targeted
J07 Aspirin of no benefit, and of potential harm, in heart failure
J05 Ginseng lowers warfarin potency for anti-coagulation
J30 Antioxidant controversy: Scientists seek measurement standards
J30 Passive smoking risk greater than previously thought
J28 Liposorbtion growing as a means of treating very high cholesterol levels
J25 New virtual reality system may aid in stroke recovery
J25 Computer-aided brain retraining increases field of vision in stroke victims
J25 New form of physical therapy restores arm function after stroke
J25 Almost half of stroke patients may be aspirin resistant
J09 Slightly elevated levels of lead, cadmium linked to peripheral arterial disease
M29 L-arginine plus exercise may have synergistic effect on CAD (in mice)
M24 US issues updated guidelines for treating hypertension in kids
M21 FDA approves troponin T test to help dx acute coronary syndrome
M19 Are "vasculotoxic" nanobacteria alive?
M16 New approaches to treating atrial fibrillation presented at conference
M06 Self-contained Abiocor heart implanted in Louisville, KY
M06 New inflammation-related gene linked to heart attacks
M04 Could vitamins increase levels of bad cholesterol?
M04 Coffee intake may increase HTN risk in minority adolescents
A19 Strict diet has dramatic effect on reducting heart disease
A14 Having a close friend can reduce the risk of heart disease
A09 Anticytokine therapy fails to help patients with chronic heart failure
A09 New calcium channel drug stops sudden cardiac death in animals
A08 NEJM: New class of drug successfully increases HDL cholesterol levels
A04 Calcium-activated K-channel mutation linked to severe diastolic hypertension
A04 Novel MRI technique provides clear images of blood flow
M31 NEJM: Icelandic study shows that CRP has only moderate predictive value for CAD
M29 Carbenoxolone may have beneficial effects on memory
M24 Activity of calcium-handling gene linked to cardiac arrhythmias
M17 Blood test may detect strokes with high sensitivity
M17 BHS-IV guidelines for hypertension management : summary
M17 British Hypertension Society publishes its guidelines
M15 Canola oil-fed cows produce milk with healthier fat profile
M12 Musical biometric feedback helps in stress management
M11 Aspirin resistance - more than just a laboratory curiosity? (pdf)
M11 Estradiol-eluting coronary stents show promising, early results (pdf)
M11 ACC 2004 conference daily news summaries
M11 Urocortins act on heart, may benefit congestive heart failure
M09 Forgetfulness tops list of reason for non-compliance with cardioprotective meds
M09 Pepine and Laura Bush on women and heart disease (ACC 2004 Ann Mtg)
M08 Cholesterol reduction: the lower, the better
M07 Folate fortification of flour may have resulted in marked fall in CV disease
M02 NIH stops estrogen-alone study because of increased stroke risk
F21 FDA approves implantable defibrillators with internet monitoring system
F21 Plant sterols added to food effective in lowering cholesterol
F17 Cheap four-drug combo lowers mortality risk by 90% post MI
F11 Institute of Medicine recommends 1.5 g/day sodium for all, even less for elderly
F09 Iceland genome project finds new gene linked to heart attacks
F09 New guidelines to prevent heart disease and stroke in women
F09 Eating mercury-contaminated fish while pregnant can cause child brain damage
F05 Bat saliva drug offers promise in treating acute stroke
F01 Moderate-fat diet results in better lipid profiles than low-fat diet
J31 Modified vitamin E molecule increases antioxidant activity 100-fold
J31 Scientists eye pills to unclog arteries
J27 Placental growth factor - a new biomarker of atherosclerotic plaque instability
J27 C-reactive protein linked to buildup of fatty plaque in arteries
J27 Statins, ACE-inhibitors, improve outcomes in patients after leg bypass surgery
J20 Melatonin may affect nocturnal blood pressure
J16 Coronary artery calcium scores useful in intermediate risk patients
J16 Italian pharma company to provide red wine ingredients in a pill
J12 Walking 1.5 miles per day can help prevent weight gain
J09 Long QT syndrome mutations may be much more common than previously thought
J08 High salt intake linked to stomach cancer risk in Japan
D31 Novel estrogen-like compound may obviate estrogen risks
D31 NEJM: 5-lipoxygenase gene tied to atherosclerosis
D18 JNC 7 Full text (.PDF format)
D16 New information links obesity and inflammation
D06 DHEA may increase number of plaque-forming foam cells, upping CV risk
D04 Can statins cause amnesia?
D01 RSNA meeting: New standards proposed for coronary artery calcium screening
D01 Apheresis for hypercholesterolemia in the news in the UK
N29 Keryx announces sulodexide open access research collaboration with U. Mich.
N28 Cleveland Clinic researchers identify heart attack gene
N25 Qualitative HDL cholesterol test (pro- or anti-inflammatory) predicts CV risk
N20 T-type calcium channels involved in coronary relaxation
N13 AHA: Cholesterol - how low should you go?
N13 Guinness beer may reduce risk of blood clotting
N12 AHA Scientific Sessions: Daily Newspaper: Wednesday Nov 12
N11 AHA Scientific Sessions newspaper: Tuesday Nov 11
N11 Tetrahydrobiopterin, an NO co-factor, may be novel anti-hypertensive agent
N11 Apoptosis of endothelial cells linked to heart risk in lupus patients
N10 AHA Meeting Sessions daily newspaper: Monday, Nov 10 (PDF)
N10 AHA Meeting Sessions daily newspaper: Sunday Nov 09 (PDF)
N10 AHA: Vasopressin blocker tolvaptan decreases fluid retention in heart failure
N04 Injected megaHDL cholesterol rapidly improves atherosclerosis in people
O31 Liquid putty used to treat cerebrovascular aneurysms
O30 FDA: Early thrombosis warning of Cordis Cypher coronary stents
O30 NEJM: Ximelagatran as good as warfarin for preventing DVT
O29 Resveratrol red wine antioxidant lowers inflammatory mediators in COPD
O29 Aspirin withdrawal may pose risks to coronary patients
O28 Lowering blood pressure immediately after a stroke can be harmful
O22 Clot retreiving wire holds promise for treating acute stroke
O17 Nitric oxide blocks exocytosis, thereby preventing inflammation
O15 Supersized cholesterol carriers the key to a long life?
O08 Pfizer Inspra (epleronone) wins FDA approval to treat CHF
O02 Stroke risk not related to dietary fat intake in men
S30 Does stress impair pressure-induced natriuresis and thereby cause kidney damage?
S30 Icelander genetic screening identifies stroke-risk gene
S30 Icelanders find that one gene that makes you fat or thin
S26 New cardiac inotropic hormone from coronary endothelium - apelin
S26 Low sodium diet has no adverse effect on blood lipids
S22 Disorder of ciliary transport linked to learning disabilities, obesity
S19 Azithromycin of no help in secondary prevention of coronary events
S18 NEJM: Herpesvirus 8 linked to primary pulmonary hypertension
S18 Hyperkalemia and creatinine increases on ACE-I: What should one do?
S16 Calcium channel blockers affect iron transport into the heart
S16 Cancer drug HDAC (histone deacetylase) halts LVH in lab animals
S15 K/DOQI dyslipidemia guidelines
S14 Do statins have a primary role in prevention? A conservative viewpoint.
S09 Smoking reduces monamine oxidase levels in the kidney and other organs
S09 Saponins in red wine may account for some beneficial CV effects
S04 NEJM: PYY hormone cuts appetite by athird
S03 Chilli pepper receptors responsible for heart attack pain
S02 DNA-repair gene protects some smokers against lung cancer
S02 DNA-repair gene protects some smokers against lung cancer
S01 Intracardiac autologous stem cell injection may eliminate need for heart tx
S01 ESC: Perindopril lowers mortality in post-MI patients
S01 Abstract search page: Eur Soc Cardiol 2003 Meeting
S01 European Society of Cardiology meeting: Highlights and reports
S01 European Society of Cardiology meeting: Highlights and reports
A30 Will handheld ultrasound device supplant the stethoscope?
A28 Health benefits of chocolate: the darker, the better
A27 VA cooperative study on homocysteine in CKD in progress
A26 CAD death reath linked to EBCT coronary artery calcium scores
A24 Resveratrol identified as life extending ingredient in red wine
A23 Three patients with Jarvik 2000 heart pump now at home
A23 Artificial heart muscle being developed at Leeds
A22 Hyperkalemia in CHF patients treated with ACE-I and spironolactone
A21 NEJM: Primary angioplasty better than fibrinolysis, even after transfer
A20 Obesity, depression, tied to CRP levels in men
A19 U.S. approves Viagra rival Levitra from Glaxo, Bayer
A18 New educational video on CV disease for African American women
A16 Study finds new approach to unclogging arteries
A13 Antioxidant vitamins help vasculature in kids with high cholesterol
A10 Endothelin converting enzyme new target for heart disease drugs
A09 US Preventive Services Task Force says to screen all adults for high BP
A05 US Natl Stroke Assoc launches patient education campaign
J31 Tangle enzyme Pin1 protects against Alzheimer disease
J29 Thyroid receptor compound effects weight loss, lowers cholesterol
J28 Push aims to lower hidden salt in food
J27 LOX-1 gene linked to heart attacks, cardiac arrest
J25 Content of addictive form of nicotine, free-base, varies widely among cigarettes
J24 Mandibular advancement splint helps patients with sleep apnea
J23 Ape diet lowers cholesterol as efficiently as do drugs
J21 Clinical chemist association weighs in on routine CRP testing
J21 Tomato-eating reduces heart disease risk by 30%
J20 Study backs do-it-yourself blood pressure checks
J19 FDA approves PLAC test to detect CV risk
J16 Pulmonary vein ablation method improves survival in atrial fibrillation patients
J16 JAMA paper puts troponin T and CRP tests for dialysis patients in the news
J13 MMWR: Cardiomyopathy and pericarditis following civilian smallpox vaccination
J13 Patients demand sirolimus-eluting CYPHER stent by brand name
J09 U.S. hypertension rates rising
J09 FDA approves pravastatin / aspirin combo pill
J05 Singer Barry White dies of hypertension, kidney failure at age 58
J27 COMET trial results show 17% lower mortality with carvedilol vs. metoprolol
J26 Hypothetical benefits of polypill - aspirin, folate, statin, ACE, touted in BMJ
J22 Brits identify genes linked to hypertension on 4 separate chromosomes
J18 HDL may increase half-life of endothelial NO synthase
J18 Genetic locus strongly linked to atrial fibrillation found on chromosome 6
J18 Pfizer unveils new anti-smoking drug
J16 Cardiovascular benefits of vitamin E and carotene questioned
J16 Cardiovascular benefits of moderate exercise challenged
J13 Patient recovers after LVAD bridges failing heart due to viral myocarditis
J13 Eur Soc Hypertension (ESH): New hypertension guidelines on-line
J11 Aspirin as effective as ticlodipine in African American stroke prevention
J10 MRI angiogram identifies stroke-prone carotid plaque
J05 New drug (mirtazapine) very promising in treatment of sleep apnea
J04 Upper arm AV fistula causes steal syndrome in IMA coronary bypass grafts
M29 E2F decoy soaking of veins used for coronary bypass grafts
M28 Physical activity can rapidly reduce dangerous visceral fat
M27 Fish oil CV protection may be mediated by prevention of sudden death
M21 Atkins diet found to be superior in two controlled trials, one in NEJM
M21 Scripps working on a nicotine vaccine
M19 Potential new benefits for statins
M19 EBCT helps in CAD risk assessment of asymptomatic individuals
M19 ASH: One in three home BP monitors give unreliable results
M19 DASH diet may act as diuretic
M16 Coronary artery disease link to second-hand smoking disputed
M15 CV risk of Chlamydia seropositivity increased when CRP is high
M14 JNC 7 now defines hypertension as pressures above 120/80
M14 JNC 7 U.S. hypertension guidelines (full text, JAMA)
M14 Am Soc Hypertens 2003 meeting abstracts available here
M13 Chiropractic treatment of the neck can be a risk factor for stroke
M06 ASN, NKF issue joint comment on ALLHAT results re ACE-I and ARBs
M06 Off-pump coronary bypass grafting leads to better outcomes
M01 Klotho gene linked to aging, atherosclerosis
M01 ASH-2003: Abstracts now available on-line
A26 Vascular Compliance talk CME/CE credits now available
A25 Heart disease in women being emphasized in the media
A25 U.S. FDA approves drug-emitting stent for heart disease
A22 Chlamydia related to age-related macular degeneration risk
A22 Multiple lifestyle changes work to lower blood pressure
A16 Progeria gene identified; yields clues to normal aging
A14 Drinking Concord grape juice lower blood pressure in hypertensive men
A11 Coffee plus alcohol shown to limit stroke-related brain damage in animals
A10 Anti-psychotic drug Risperdal linked to increased stroke risk
A08 Verapamil helps control BP in heart patients; associated with good outcome
A07 Key role of HDL emphasized in study presented at ACC-Chicago
A05 American Stroke Association updates urgent stroke care guidelines
A05 Osteoporosis linked to heart disease in women
A04 Dr. Arthur Guyton dies in car accident
A04 Aortic stiffness related to stroke incidence in hypertensive patients
A03 Epleronone improves CV outcome post MI
A03 Ximelagatran may be safer, more efficacious than warfarin to prevent stroke
A02 ACC: Irbesartan, amlodpine show similar rates of CV events in type 2 DN
A02 ACC: Sirolimus-coated stents show reduced restenosis rates
A01 ACC: Search 2003 Meeting abstracts (Am Coll Cardiol)
A01 ACC: Late breaking clinical trials in cardiology
A01 Damage from low-dose X-rays may be greater than previously thought
M31 Drug-eluting stents appear to be cost-effective
M29 MMWR: Cardiac events following smallpox vaccination. USA 2003
M27 Surgical treatment of atrial fibrillation gaining in popularity
M25 African Americans prone to hypertensive retinopathy
M25 Cells from marros may stick to and worsen coronary artery plaques
M20 ALLHAT principals, NHLBI argue over study result interpretation
M19 NEJM: Soluble CD40 ligand and abciximab in acute coronary syndromes
M17 Cardiovascular disease in CKD: Seminars in Dialysis issue
M16 Stopping hepatic lipoprotein secretion in mice stops atherogenesis<