2018 HDCN-- Weekly Update
July 31, 2019
Advances in Chronic Kidney Disease 2019
Renal Research Institute (New Orleanas; January, 2019)  


Welcome/Program Overview
Peter Kotanko, MD

Virtual Reality Based Training In Nephrology - Has The Future Arrived
Boris Kantzow, MD

Telemedicine in PD Patients
Martin K. Kuhlmann. MD

Round Table: Is it time to Revise the Categorization of Kidney Disease?

Harvard Intensive Review of Nephrology 2018
Brigham and Women's Hospital Department of Medicine (Boston, MA; August, 2018)  


Renal Physiology for the Boards
Melanie P. Hoenig MD

WILEY PUBLISHING, publishers of many journals and books of interest to kidney disease professionals, including the journals Am J Transplantation, Seminars in Dialysis, and Hemodialysis International.
For more information about Wiley Publishing please visit

Editor's Announcement


Intensive Review of Nephrology
Fairmont Copley Plaza • Aug 5 - 9, 2019
Boston, MA

Program link

Intensive Review of Nephrology

The Comprehensive Clinical Update and Board Review

With over 70 interactive lectures, case discussions, and board preparation sessions, this CME program provides a comprehensive review of state-of-the-art nephrology practices offered by the clinical faculty of Harvard Medical School.

It offers accelerated learning for:

Clinicians seeking a practical and comprehensive review that ensures they are up to date across all major areas of nephrology:
  1. The latest options for diagnosis: what to choose, when, and why
  2. Current evidence-based treatment and care management strategies to optimize patient outcomes
  3. Improved approaches to common and complex clinical challenges
  4. Navigating clinical controversies
  5. How to avoid medical mistakes
Physicians preparing to certify or recertify and are seeking a thorough, proven preparatory course in advance of their taking the Nephrology ABIM board examination.


The aldosterone/renin ratio predicts cardiometabolic disorders in subjects without classic primary aldosteronism (Am J Hypertens)
Effect of dapagliflozin on heart failure and mortality in type 2 diabetes mellitus (Circulation)
Serum and urine albumin and response to loop diuretics in heart failure (Clin J Am Soc Nephrol)
Clinical pharmacology of antihypertensive therapy for the treatment of hypertension in CKD (Clin J Am Soc Nephrol)
Effect of a walnut diet on office and 24-hour ambulatory blood pressure in elderly individuals: Findings From the WAHA Randomized Trial (Hypertens)
Aligning adult and pediatric blood pressure guidelines (Hypertens)
Small amounts of inorganic nitrate or beetroot provide substantial protection from salt-induced increases in blood pressure (Hypertens)
Blood pressure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference (Kidney Int)
Fournier gangrene associated with sodium-glucose cotransporter-2 inhibitors: a review of spontaneous postmarketing cases (Ann Intern Med)
Patent foramen ovale and ischemic stroke in patients with pulmonary embolism: a prospective cohort study (Ann Intern Med)
Empagliflozin and the risk of heart failure hospitalization in routine clinical care (Circulation)
Sodium-glucose cotransporter inhibitors: beyond glycaemic control (Clin Kidney J)
International consensus on risk management of diabetic ketoacidosis in patients with type 1 diabetes treated with sodium-glucose cotransporter (SGLT) inhibitors (Diabet Care)
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy (N Engl J Med)
Modeled daily ingested, absorbed and bound phosphorus: new measures of mineral balance in hemodialysis patients (Am J Nephrol)
Relationship between poor olfaction and mortality among community- dwelling older adults: a cohort study (Ann Intern Med)
Should viscous fiber supplements be considered in diabetes control? results from a systematic review and meta-analysis of randomized controlled trials (Diabet Care)
Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo- controlled trial (Lancet)
Low testosterone is associated with frailty, muscle wasting and physical dysfunction among men receiving hemodialysis: a longitudinal analysis (Nephrol Dial Transplant)
Aquaporin 11 rs2276415 variant and progression of chronic kidney disease (Nephrol Dial Transplant)
Initiating haemodialysis twice-weekly as part of an incremental programme may protect residual kidney function (Nephrol Dial Transplant)
Monthly high-dose vitamin D supplementation does not increase kidney stone risk or serum calcium: results from a randomized controlled trial (Am J Clin Nutr)
Mortality and kidney transplantation outcomes among hepatitis C virus- seropositive maintenance dialysis patients: a retrospective cohort study (Am J Kidney Dis)
Performance of the T2-bacteria panel for diagnosing bloodstream infections: a diagnostic accuracy study (Ann Intern Med)
Effect of dialysate potassium and lactate on serum potassium and bicarbonate concentrations during daily hemodialysis at low dialysate flow rates (BMC Nephrol)
Prophylactic use of implantable cardioverter-defibrillators in the prevention of sudden cardiac death in dialysis patients: The prospective randomized ICD2 Trial (Circulation)
Effects of arteriovenous fistula ligation on cardiac structure and function in kidney transplant recipients (Circulation)
Clinical pharmacology considerations in pain management in patients with advanced kidney failure (Clin J Am Soc Nephrol)
Acute effects of haemodialysis on circulating microparticles (Clin Kidney J)
Renal perfusion during hemodialysis: intradialytic blood flow decline and effects of dialysate cooling (J Am Soc Nephrol)
Types of erythropoietin-stimulating agents and mortality among patients undergoing hemodialysis (J Am Soc Nephrol)
Cardiovascular outcomes of calcium-free vs calcium-based phosphate binders in patients 65 years or older with end-stage renal disease requiring hemodialysis (JAMA Intern Med)
Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference (Kidney Int)
The effect of dry-weight reduction guided by lung ultrasound on ambulatory blood pressure in hemodialysis patients: a randomized controlled trial (Kidney Int)
Dietary fiber intake, myocardial injury, and major adverse cardiovascular events among end-stage kidney disease patients: a prospective cohort study (Kidney Int Rep)
The promise of bioimpedance for volume management in American dialysis patients: An unfulfilled opportunity (Semin Dial)
Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management (BMC Nephrol)
Rate of correction of hypernatremia and health outcomes in critically ill patients (Clin J Am Soc Nephrol)
Autologous hematopoietic stem cell transplantation for refractory lupus nephritis (Clin J Am Soc Nephrol)
Fruit and vegetable treatment of chronic kidney disease-related metabolic acidosis reduces cardiovascular risk better than sodium bicarbonate (Am J Nephrol)
Sodium zirconium cyclosilicate among individuals with hyperkalemia (Clin J Am Soc Nephrol)
An updated classification of thrombotic microangiopathies and treatment of complement gene variant-mediated thrombotic microangiopathy (Clin Kidney J)
Efficacy and safety of empagliflozin in renal transplant recipients with posttransplant diabetes mellitus (Diabet Care)
A randomized trial of magnesium oxide and oral carbon adsorbent for coronary artery calcification in predialysis CKD (J Am Soc Nephrol)
Hyponatremia in the dialysis population (Kidney Int Rep)


 H: Pathophysiology -- Heart in hypertension
Acetazolamide Therapy in Patients with Heart Failure: A Meta-Analysis
 H: Pathophysiology -- Sleep, sleep apnea
Association of Chronic Insomnia with Protein Energy Wasting in CKD
 H: Pathophysiology -- Coagulation abnormalities
Association of Major Adverse Cardiac Events in Patients Taking Direct Oral Anticoagulants (DOACs) in Patients with CKD
Direct Oral Anticoagulants vs Warfarin: Stroke Outcomes in CKD Patients
 H: Exam and lab tests -- Ambulatory monitoring
Ambulatory Blood Pressure (ABP) Is More Important Risk Factor to Renal Outcome in CKD Patients Than Office Blood Pressures
 H: Special problems -- Endocrine hypertension
Clinical Feature and Diagnosis of Primary Hyperaldosteronism

 Basic hemodialysis -- Vascular Access: graft/fistula
Risks and Benefits of Antiplatelet Agents and Anticoagulants on Preventing Vascular Access Dysfunction in Hemodialysis Patients
New Approach for Assessing Vascular Stiffness in Patients with Hemodialysis
 Basic hemodialysis -- Dialysis machines
Evaluation of Albumin Loss During Hemodialysis with Theranova® Medium Cut- Off (MCO) Dialyzer: Six Months Follow-Up
 Basic hemodialysis -- Complications (acute)
Comparison of Indicators of Fluid Overload in Hemodialysis Patients
The Total IV Iron Burden and Insulin Sensitivity in ESRD
Effect of a Hemodialysis Treatment on Platelet Function Using PFA-100
Accuracy of Dialysate Sodium from Dialysate Conductivity Compared to Measured Sodium: A Quality Assurance Study
Reduction in Mean Patient Body Weights and Blood Pressures Were Observed During a Fluid Management Quality Improvement (QI) Project Utilizing Relative Blood Volume Monitoring (RBV-M)
Impact of PEAK Methodology on Interdialytic Weight Gain: A Multi-center Experience
Development of a Microparticle-Based Bio-marker of Hemodialysis Induced Vascular Injury
 Basic hemodialysis -- Continuous therapies
Chloride Increase Following Continuous Renal Replacement Therapy (CRRT) Initiation Is Associated with Mortality
 Basic peritoneal dialysis -- PD catheters
Abdominal Rectus Thickening as a Predictor of Peritoneal Catheter Primary Dysfunction
 CRF: Problem Areas -- Rehabilitation, exercise, quality of life
Profiles of Physical Activity in Hemodialysis Patients Randomized into the HDFIT Trial
Relative Sarcopenia and Mortality and the Modifying Effects of CKD and Adiposity
 CRF by problem area -- Cost effectiveness, CQI, Guidelines
Relationships Between Satisfaction Scores and Outcomes in Dialysis Patients
Comparison of Hospitalization Rate in Automatized Peritoneal Dialysis Patients with and Without Remote Management Program in Colombia
Impact of Peritoneal Dialysis (PD) Remote Monitoring on PD Services
 CRF: Problem areas -- Pre-ESRD care, initiation of dialysis
The Prevalence of Uremic Symptoms and Their Association with Adverse Outcomes in CKD
 CRF by problem area -- Progression
DUPDN - Diagnostic Urinary Panel for Diabetic Nephropathy: A Model to Predict Progressive CKD
Associations of Urinary NGAL and RBP with Nephropathy and Their Roles in Normoalbuminuric Renal Insufficiency in T2DM
Assessment of the Relationship Between the 2010 Pathologic Classification and Renal Outcomes in Patients with Diabetic Nephropathy: A Meta-Analysis
 CRF by organ system -- Nutrition, Inflammation
Pre-ESRD 24 Hour Urine Creatinine Changes and Post-ESRD Mortality
Change in Body Composition over Time and Its Association with Survival Among Patients on Hemodialysis
Effects of Body Fat Accumulation During PD on Mortality and Technique Failure: Is There a Difference by PD Duration?
 CRF by problem area -- Anemia/Erythropoietin/Iron
The Effect of Citrate Dialysate on Clot Formation and Anemia in Hemodialysis Patients
 CRF by problem area -- Acid-base in dialysis
Effects of Treatment of Metabolic Acidosis in CKD: A Systematic Review and Meta-Analysis
Serum Chloride and All-Cause Mortality in CKD
 CRF by problem area -- Bone disease/Ca-P/PTH
Calcium Mass Balance During Hemodialysis: A Comparison of Different Dialysate Calcium Concentrations Including Citrate-Acid Calcified Dialysate
 CRF by organ system -- Cardiovascular/Hypertension
Liver Stiffness Reflecting Renal Congestion Predicts Renal Outcome in Patients with Congestive Heart Failure
Duration of Dual Antiplatelet Therapy in Patients with CKD and Drug-Eluting Stents: A Meta-Analysis
 CRF by organ system -- Endocrine
Comparison of Low and Standard Dose Adrenocorticotropic Hormone (ACTH) Stimulation Test in the Diagnosis of Adrenal Insufficiency in Peritoneal Dialysis Patients

 Acid-base/Lytes -- Hyponatremia
Simplified, Simulated Sodium Kinetic Modeling for Correction of Hyponatremia by Continuous Venovenous Hemofiltration
Continues Renal Replacement Therapy: A Simple Approach for Treating Hyponatremia
Hyponatremia Associated with Development of Sepsis
Optimal Cut-Off Level of Urine Sodium in Differentiating Hypovolemic Hyponatremia and SIADH
 Acid-base/Lytes -- Metabolic acidosis
Accurate Estimation of Arterial pH from Venous pCO2 and Venous CO2: An Easy Solution to an Old Problem
Etiology of the Elevated ?AG/?HCO3 Ratio in Lactic Acidosis: Time for Another Delta?
 Acid-base/Lytes -- Metabolic alkalosis
Carbonic anhydrase Inhibitors (CAI) Use in Patients with Respiratory Failure and Metabolic Alkalosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
 Acid-base/Lytes -- Hyperkalemia
Efficacy and Safety of Patiromer in Participants with Diabetes: A Pooled Analysis
The Association of Sodium Polystyrene Sulfate (Kayexelate™) Use and Adverse Gastrointestinal Events
 Acid-base/Lytes -- Hypomagnesemia
Tacrolimus Trough Levels and Risk of Hypomagnesemia in Renal Transplant Recipients
 Acid-base/Lytes -- Hypocalcema
Anion Gap (AG) Improves the Prediction of Ionized Hypocalcemia (HC) in Critical Care
 Proteinuria/Hematuria -- Diabetes
Renal Biopsy in Diabetic Patients: Preliminary Results of the Spanish Multicenter Study BIODIAB-GLOSEN-GEENDIAB
 Transplant -- Transplantation
Peritoneal Dialysis After Renal Transplant Failure: A Different Beast Altogether