February 19, 2019
Advances in Chronic Kidney Disease 2018
Renal Research Institute (Lake Buena Vista, FL; February, 2018)  


Dialyzability of commonly used drugs
Matthew A. Weir, MD

Why are we using diuretics in our ESRD patients?
Mark Unruh, MD

Novel insights into pathogenesis and prevention of intradialytic hypotension
Frank van der Sande, MD

Dialysis in the elderly - Do we need a special approach?
Martin Kuhlmann, MD

WILEY PUBLISHING, publishers of many journals and books of interest to kidney disease professionals, including the journals Am J Transplantation, Seminars in Dialysis, and Hemodialysis International.
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Fibroblast growth factor-23, heart failure risk, and renin-angiotensin -aldosterone-system blockade in hypertension: The MESA Study (Am J Hypertens)
Dietary phosphorus and ambulatory blood pressure in African Americans: The Jackson Heart Study (Am J Hypertens)
Effects of intensive blood pressure lowering on kidney tubule injury in CKD: A longitudinal subgroup analysis in SPRINT (Am J Kidney Dis)
Effect of intensive blood pressure lowering on kidney tubule injury: Findings from the ACCORD trial study participants (Am J Kidney Dis)
Novel and emerging therapeutics for primary prevention of cardiovascular disease (Am J Med)
Inferior vena cava filters in patients with recurrent pulmonary embolism (Am J Med)
Catheter ablation of atrial fibrillation in patients with heart failure: a meta-analysis of randomized controlled trials (Ann Intern Med)
Long-term incense use and the risk of end-stage renal disease among Chinese in Singapore: the Singapore Chinese health study (BMC Nephrol)
A three-arm randomized trial of different renal denervation devices and techniques in patients with resistant hypertension (RADIOSOUND-HTN) (Circulation)
Loss of gut microbiota alters immune system composition and cripples postinfarction cardiac repair (Circulation)
Sustainability of blood pressure reduction in Black barbershops (Circulation)
Introduction: standards of medical care in diabetes - 2019 (Diabet Care)
Prevalence of hypertension in children: applying the new American Academy of Pediatrics clinical practice guideline (Hypertens)
Role of dietary K+ in natriuresis, blood pressure reduction, cardiovascular protection, and renoprotection (Hypertens)
Out-of-clinic sympathetic activity is increased in patients with masked uncontrolled hypertension (Hypertens)
Associations of fenofibrate therapy with incidence and progression of ckd in patients with type 2 diabetes (Kidney Int Rep)
Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia (N Engl J Med)
Black-White difference in the impact of long-term blood pressure from childhood on adult renal function: The Bogalusa Heart Study (Am J Hypertens)
Role of high-dose beta-blockers in patients with heart failure with preserved ejection fraction and elevated heart rate (Am J Med)
Management of hyperglycemia in type 2 diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (Diabet Care)
SGLT Inhibitors for Type 1 Diabetes: An Obvious Choice or Too Good to Be True? (Diabet Care)
Creatinine rise during blood pressure therapy and the risk of adverse clinical outcomes in patients with type 2 diabetes mellitus: A Post Hoc Analysis of the ACCORD-BP RCT (Hypertens)
Cardiovascular phenotype of elevated blood pressure differs markedly between young males and females: The Enigma Study (Hypertens)
Diagnostic thresholds for blood pressure measured at home in the context of the 2017 hypertension guidelineAnalysis From 2 US Cohorts (Hypertens)
Keep an eye on the eye symptoms of your dialysis patient (Am J Med)
IHDIP: a controlled randomized trial to assess the security and effectiveness of the incremental hemodialysis in incident patients (BMC Nephrol)
Uremic toxin indoxyl sulfate promotes proinflammatory macrophage activation via the interplay of OATP2B1 and Dll4-Notch signaling (Circulation)
Patterns of beverages consumed and risk of incident kidney disease (Clin J Am Soc Nephrol)
Association of continuation of loop diuretics at hemodialysis initiation with clinical outcomes (Clin J Am Soc Nephrol)
Hyperphosphataemic tumoral calcinosis (Lancet)
Partial oral versus intravenous antibiotic treatment of endocarditis (N Engl J Med)
Intravenous iron in patients undergoing maintenance hemodialysis (N Engl J Med)
PTH assays in dialysis patients: Practical considerations (Semin Dial)
Febuxostat therapy for patients with stage 3 CKD and asymptomatic hyperuricemia: a randomized trial (Am J Kidney Dis)
Effects of coffee intake on incident chronic kidney disease: a community-based prospective cohort study (Am J Med)
Effect of oral alfacalcidol on clinical outcomes in patients without secondary hyperparathyroidism receiving maintenance hemodialysis: The J-DAVID randomized clinical trial (J Am Med Assoc)
A randomized controlled trial of alanyl-glutamine supplementation in peritoneal dialysis fluid to assess impact on biomarkers of peritoneal health (Kidney Int)
Negative effect of vitamin D on kidney function: a Mendelian randomization study (Nephrol Dial Transplant)
Monitoring urine flow to prevent overcorrection of hyponatremia: derivation of a safe upper limit based on the Edelman equation (Am J Kidney Dis)
Asian Americans & chronic kidney disease in a nationally representative cohort (BMC Nephrol)
Variations in risk of end-stage renal disease and risk of mortality in an international study of patients with type 1 diabetes and advanced nephropathy (Diabet Care)
Decreasing cumulative incidence of end-stage renal disease in young patients with type 1 diabetes in Sweden: a 38-year prospective nationwide study (Diabet Care)
A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis (Kidney Int)
Efficacy and safety of mycophenolate mofetil versus levamisole in frequently relapsing nephrotic syndrome: an open-label randomized controlled trial (Kidney Int)
Calcineurin inhibitors with reduced-dose steroids as first-line therapy for focal segmental glomerulosclerosis (Kidney Int Rep)
A multidisciplinary approach for the management of severe hyponatremia in patients requiring continuous renal replacement therapy (Kidney Int Rep)
Caplacizumab treatment for acquired thrombotic thrombocytopenic purpura (N Engl J Med)
B-cell therapy in lupus nephritis: an overview (Nephrol Dial Transplant)
Long-term follow-up of a combined rituximab and cyclophosphamide regimen in renal anti-neutrophil cytoplasm antibody-associated vasculitis (Nephrol Dial Transplant)
Measurement of glomerular filtration rate in patients undergoing obesity surgery (BMC Nephrol)
Relationship between caffeine intake and autosomal dominant polycystic kidney disease progression: a retrospective analysis using the CRISP cohort (BMC Nephrol)
Management of autosomal-dominant polycystic kidney disease - state-of- the-art (Clin Kidney J)
An open-label randomized controlled trial of low-dose corticosteroid plus enteric-coated mycophenolate sodium versus standard corticosteroid treatment for minimal change nephrotic syndrome (Kidney Int)
C3 glomerulonephritis secondary to mutations in factors H and I: rapid recurrence in deceased donor kidney transplant effectively treated with eculizumab (Nephrol Dial Transplant)
Urinary hypoxia: an intraoperative marker of risk of cardiac surgery-associated acute kidney injury (Nephrol Dial Transplant)


 H: Exam and lab tests -- Arm cuff
Application of New Hypertension Guidelines to Renal Transplant Recipients: Impact on Cardiovascular Outcome and Graft Survival
Long-Term Kidney Effects of Intensive (INT) SBP Lowering in Persons with Type 2 Diabetes Mellitus (T2DM): ACCORD BP and ACCORDION
The Effect of Intensive Blood Pressure Lowering on Kidney Tubule Injury in a Subgroup of Participants in the ACCORD Trial
 H: Non drug therapy -- Dietary/electrolyte therapy
The DASH Diet and Blood Pressure among Black Americans with and without CKD: The Jackson Heart Study
 H: Special problems -- Outcomes
Relationship of Systolic Blood Pressure with GFR Decline in Kidney Transplant Recipients: The FAVORIT Trial
The Effect of Intensive Blood Pressure Lowering on Markers of Mineral Metabolism in Persons with CKD in SPRINT
 H: Special problems -- Obesity, Insulin Resistance
Association of Visceral Obesity After Kidney Transplantation with Graft Survival in Living Kidney Transplant Recipients: A Retrospective Cohort Study
Effect of Obesity on Transplant Outcome One Year Post Kidney Transplant
Advanced Glycation End Products and Risk of Late Graft Failure and Cardiovascular Mortality in Renal Transplant Recipients: A Prospective Cohort Study
Empagliflozin in Posttransplantation Diabetes Mellitus: Effect on Glucose Metabolism and Fluid Volume
Liraglutide May Be Safe After Kidney Transplantation
Linagliptin May Be Safe After Kidney Transplant
Prevalence of Gout in the Surviving US Solid Organ Transplant Population

 Basic hemodialysis -- Complications (acute)
A Randomized Controlled Trial of Albumin Versus Saline for the Prevention of Intradialytic Hypotension in Hypoalbuminemic Patients
Using IVC Collapsibility and Lung Ultrasound to Determine Ultrafiltration Goal in Hemodialysis Patients
 Basic hemodialysis -- New dialysis methods, hemodiafiltration
Online Haemodiafiltration Improves Inflammatory State in Dialysis Patients: A Longitudinal Study
 CRF by problem area -- Progression
Predictive Value of Current Biomarkers for Early Reversal of AKI
Higher eGFR at Ten Years in CKD Stage 2 Pts treated with Chronic Oral NaHCO3 despite no Metabolic Acidosis is associated with prevented worsening of underlying Acid retention
Serial FGF23 Concentrations and Risk of ESRD: The Chronic Renal Insufficiency Cohort (CRIC) Study
Febuxostat for Patients with CKD Stage G3 with Asymptomatic Hyperuricemia: A Randomized Trial
Change in Albuminuria and Subsequent Risk of ESRD: A Consortium Meta- Analysis
 CRF by organ system -- Nutrition, Inflammation
Fruit and Vegetable Consumption and Cardiovascular Mortality in Renal Transplant Recipients: A Prospective Cohort Study
 CRF by problem area -- Anemia/Erythropoietin/Iron
Enarodustat (JTZ-951), an Oral HIF-PH Inhibitor, Elevates and Maintains Hemoglobin Levels over 30 Weeks in Japanese Anemic Patients with CKD Not on Dialysis
Efficacy and Safety of Daprodustat on Anemia Management in Japanese Hemodialysis Patients Not Using Erythropoiesis-Stimulating Agents
 CRF by problem area -- Bone disease/Ca-P/PTH
Progression of Cardiovascular Calcification in Renal Transplant Recipients
Vascular Calcification Slows but Does Not Regress After Renal Transplantation
A Prospective Observational Study Comparing Bone Loss in Renal Transplant and Dialysis Patients
Effects of Denosumab on Bone Metabolism and Bone Mineral Density in Kidney Transplant Patients: A Meta-Analysis
Change in FGF23 and PTH1-84 and Subsequent Cardiovascular and Renal Events in Patients with Advanced CKD
Adjustment for ProBNP Substantially Attenuates Prognostic Implications of Plasma FGF23 Levels in CKD
Serum Phosphorus & Phosphate Binder (PB) Pills/Day among Hemodialysis Pts prescribed Sucroferric Oxyhydroxide (SO) for a year compared to pts who discontinue SO & are prescribed other PB
Effects of Patiromer on Markers of Mineral Metabolism in Patients with Hyperkalemia and Hyperphosphatemia
Hyperphosphatemia and Acid-Base Equilibrium Disorders Are Newly Recognized Risk Factors for M”nckeberg?s Sclerosis of Vascular Access Artery
Intestinal Phosphorus Absorption Assessment by Kinetic Modeling of 33P Radiotracer in Hemodialysis Patients
Evaluation of Intact and Biointact PTH Assays in Chronic Hemodialysis Patients
Hypoparathyroidism and Malnutrition ? Two Sides of the Same Coin?
 CRF by problem area -- Drug use in CRF
Longer-Interval Regimen of Colistin Reduces Nephrotoxicity in Kidney-on-a- Chip
NSAID Use and NSAID-Associated AKI Before and After Implementation of Pennsylvania?s Prescription Drug Monitoring Program
Risk of AKI and Hyperkalemia Among Older Patients Prescribed Non-Steroidal Anti-Inflammatory Drugs
Prevention of Cisplatin-Induced AKI by Magnesium Supplementation: A Systematic Review and Meta-Analysis

 Acid-base/Lytes -- Metabolic acidosis
Serum Bicarbonate Levels Are Associated with Graft Survival and Mortality in Swiss Kidney Transplant Recipients
A Multicenter, Randomized Pilot Study of Oral Sodium Bicarbonate Supplementation in Non- to Mildly-Acidotic CKD: The BASE Pilot Study
The Effects of Sodium Bicarbonate in CKD Stages 3 and 4: A Randomized, Placebo-Controlled, Multi-Center Clinical Trial
 Acid-base/Lytes -- Hypomagnesemia
Serum Magnesium Value at 1 Year After Initiation of Hemodialysis Is a Significant Predictive Factor of All-Cause Mortality
Hypomagnesemia and Body Composition in Maintenance Hemodialysis Patients
Hypomagnesemia May Not Cause Increased Mortality as Agent Provocateur in Maintenance Hemodialysis Patients
 Etiologic index -- Reduced circulatory volume/sepsis/hepatorenal
Comparison Between Creatinine vs Urinary Output Criteria in RIFLE and KDIGO Definitions for AKI Post Major Elective Non-Vascular Abdominal Surgeries
 ARF etiology -- Hemolytic/uremic syndrome and TTP
Platelet Count and Serum Creatinine in the Differential Diagnosis of TMA: An Analysis from the CESAR Study
 Proteinuria/Hematuria -- Lupus nephritis
A Phase III Study of Abatacept on Standard of Care in Patients with Active Class III or IV Lupus Nephritis
Correlation of Albuminuria and Hypoalbuminemia with Area Under the Curve Levels of Mycophenolic Acid in Lupus Nephritis